Smoking allowed: Is hospital policy a liability risk?

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Smoking allowed: Is hospital policy a liability risk?

Dear Dr. Mossman:

I work at a state mental hospital where all patients are adults who are court-committed, and at least 75% of them smoke. The hospital allows smoking in part of the only outdoor area where patients—smokers and nonsmokers—may go while in our most restrictive treatment phase. Patients come to us after spending at least 2 weeks in nonsmoking facilities where smokers receive nicotine replacement therapy. If patients want to smoke but have no money, in the past our hospital provided “unit cigarettes.”

In my state, a court commitment means the patient lacks the capacity to make decisions about psychiatric care. Of course nicotine is a psychoactive drug. If a patient starts smoking while in our care, would the hospital be liable for health-related expenses the patient may later incur?—Submitted by “Dr. A”

Speaking as one colleague to another about malpractice liability, letting psychiatric patients smoke is not breaching the standard of care toward smoking patients. But you care for nonsmoking patients as well, and other types of liability besides malpractice exist.

Doctors have moral duties for lots of things we can’t be sued for. Dr. A is right to be concerned. To explain, we’ll look at:

  • changes in attitudes about smoking
  • the link between smoking and mental illness
  • smoking bans in psychiatric facilities
  • malpractice potential
  • other issues Dr. A’s hospital should consider, such as offering patients assistance with smoking cessation.

Changing attitudes about smoking

Thirty years ago, doctors smoked during medical meetings, and smoking on airplanes and in public was commonplace. I worked at an adolescent inpatient unit, and line staff carried lighters. We thought lighting kids’ cigarettes was a legitimate way to establish rapport. Times and attitudes have changed. No hospital condones smoking these days, let alone smoking by minor patients. Since the Surgeon General first declared in 1964 that smoking was hazardous, U.S. adult smoking rates have dropped from 42% to under 20%.1

In the early 1990s, California issued the first statewide ban on smoking in work-places, including bars and restaurants.2 Nearly 3,000 state or local jurisdictions require workplaces and/or commercial establishments to be smoke-free.3 Recently, the legislature in Virginia—a major tobacco-producing state—voted to prohibit smoking in restaurants,4 and many other state governments are considering smoking bans. Smoking bans are intended to protect nonsmokers—especially children—from risks of secondhand smoke,5 but they also discourage individuals from taking up the habit6 and encourage smokers to quit.7

DO YOU HAVE A QUESTION ABOUT POSSIBLE LIABILITY?

  • Submit your malpractice-related questions to Dr. Mossman at douglas.mossman@dowdenhealth.com.
  • Include your name, address, and practice location. If your question is chosen for publication, your name can be withheld by request.
  • All readers who submit questions will be included in quarterly drawings for a $50 gift certificate for Professional Risk Management Services, Inc’s online marketplace of risk management publications and resources (www.prms.com).

Smoking and mental illness

Persons with serious psychiatric disorders have smoking rates 2 to 3 times higher than those of the general population.8,9 As Dr. A notes, nicotine is a psychoactive drug. Smoking may be a genuine—although ultimately unhealthy—form of self-medication and may have positive psychological effects, such as antidepressant activity for many mentally ill persons.10,11 The Joint Commission on Accreditation of Healthcare Organizations banned smoking in hospitals in 1992 but made an exception for psychiatric units. Out of sympathy for patients and concern about what could happen when they are deprived of a substance they intensely crave, many psychiatric wards continue to accommodate smokers.12

What some institutions have done

An increasing number of psychiatric facilities have instituted or are considering bans on smoking.13 The first psychiatric smoking bans were implemented despite fears that patient violence would increase and opposition from hospital employees—a group that often includes smokers. Experience shows that although not all smoking bans are successful or problem-free,14 they usually cause fewer problems than anticipated. We also know what factors help make smoke-free programs successful (Table).15

Table

Smoke-free plans that work: How to clear the air

• Take time—more than 6 months—to plan smoke-free initiatives
Supply patient and staff smokers with nicotine replacement therapy
Present clear, consistent, visible leadership
Encourage cohesive teamwork
Provide extensive education and training for staff
Reduce staff smoking rates
Offer programs and education to promote smoking cessation among staff members
Enforce nonsmoking policies
Source: Adapted from reference 15

Aggression, seclusion, discharges against medical advice, and “prn” medication use do not increase after smoking bans,5,16,17 and many patients experience health benefits.18 After discharge, however, most patients resume tobacco use.11,19,20

 

 

Smoking bans have been opposed on grounds that they abridge psychiatric patients’ rights and are unduly coercive.21,22 In the United States and United Kingdom, however, legal actions to block smoking bans have not succeeded, and courts have not recognized a fundamental “right to smoke.”23-25

Is allowing smoking malpractice?

Now that many psychiatric facilities have ended smoking, clinicians may worry—as does Dr. A—that we could incur malpractice liability if we let inpatients smoke. One of my University of Cincinnati law students, Amanda Smith, and I researched this topic and found no case report that said letting psychiatric inpatients smoke violated the standard of care.

This makes sense, because in the malpractice context, a practitioner is judged by what prudent, similarly situated physicians with similar training would do in similar circumstances. Many psychiatric facilities still permit smoking, so letting patients smoke does not breach the standard of care, even if it seems negligent.26

The ill effects of smoking accrue over years, not weeks or months. Almost all patients who smoke in hospitals also have smoked before hospitalization, and most smokers who are barred from smoking while inpatients resume soon after discharge. To succeed, a malpractice lawsuit must show that the defendant’s actions caused damages. A jury might find it hard to conclude that a permissive hospital smoking policy was the primary cause of a long-term smoker’s health problems.

4 other concerns

Nonsmokers’ rights. Arrangements at Dr. A’s hospital expose nonsmokers to secondhand cigarette smoke, which raises the possibility of legal action by nonsmokers. In 1993, the U.S. Supreme Court held that a prison inmate’s heavy exposure to secondhand smoke violated the Eighth Amendment ban on cruel and unusual punishment.27 Involuntary hospitalization is not punishment, but suits such as this might be brought on other grounds, such as violation of patients’ civil rights.28

Competence. In some states, civil commitment requires a finding that the respondent is not competent to make treatment decisions. Can persons who are not competent to make treatment decisions make good decisions about whether to smoke? Shouldn’t the hospital deal with patients’ nicotine dependence more therapeutically—and paternalistically—by providing nicotine replacement and encouraging smoking cessation? Shouldn’t the hospital also discourage patients who don’t smoke from starting?

Protecting patients. Dr. A’s hospital provides cigarettes to patients. Though compassion may be the motive, is the hospital failing to protect its incompetent patients and abetting their self-injurious behavior?

Helping smokers quit. Does the hospital offer treatment to help smokers quit? Although the problems that lead to civil commitment are immediate and serious, addressing long-term health issues is consistent with treating acute psychiatric crises. Many hospitals that permit smoking also encourage participation in smoking-cessation programs. Having these available to patients might make claims that the hospital failed in its duties to care for patients less plausible.

Related resources

References

1. Centers for Disease Control and Prevention. Cigarette smoking among adults—United States, 2007. Available at: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5745a2.htm. Accessed April 10, 2009.

2. Calif. Labor Code § 6404.5.

3. American Nonsmokers’ Rights Foundation. Overview list–how many smokefree laws? Available at: http://www.no-smoke.org/pdf/mediaordlist.pdf. Accessed February 11, 2009.

4. Kumar A. Va. House approves ban on smoking: most restaurants would be affected. Washington Post. February 10, 2009: Page A01.

5. U.S. Department of Health and Human Services. The health consequences of involuntary exposure to tobacco smoke: a report of the Surgeon General. Rockville, MD: U.S. Department of Health and Human Services; 2006.

6. Siegel M, Albers AB, Cheng DM, et al. Local restaurant smoking regulations and the adolescent smoking initiation process: results of a multilevel contextual analysis among Massachusetts youth. Arch Pediatr Adolesc Med. 2008;162(5):477-483.

7. Longo DR, Feldman MM, Kruse RL, et al. Implementing smoking bans in American hospitals: results of a national survey. Tob Control. 1998;7(1):47-55.

8. Lasser K, Boyd JW, Woolhandler S, et al. Smoking and mental illness: a population-based prevalence study. JAMA. 2000;284(20):2606-2610.

9. Morris CD, Giese AA, Turnbull JJ, et al. Predictors of tobacco use among persons with mental illnesses in a statewide population. Psychiatr Serv. 2006;57(7):1035-1038.

10. Cattapan-Ludewig K, Ludewig S, Jaquenoud Sirot E, et al. Why do schizophrenic patients smoke? Nervenarzt. 2005;76(3):287-294.

11. El-Guebaly N, Cathcart J, Currie S, et al. Public health and therapeutic aspects of smoking bans in mental health and addiction settings. Psychiatr Serv. 2002;53(12):1617-1622.

12. Williams JM. Eliminating tobacco use in mental health facilities: patients’ rights, public health, and policy issues. JAMA. 2008;299(5):571-573.

13. Parks J, Jewell P, eds,, Burke M. Technical report on smoking policy and treatment in state operated psychiatric facilities. Alexandria, VA: National Association of State Mental Health Program Directors Medical Directors Council; 2006. Technical Report 12.

14. Campion J, Lawn S, Brownlie A, et al. Implementing smoke-free policies in mental health inpatient units: learning from unsuccessful experience. Australas Psychiatry. 2008;16(2):92-97.

15. Lawn S, Campion J. Smoke-free initiatives in psychiatric inpatient units: a national survey of Australian sites. Adelaide, Australia: Flinders University; 2008.

16. Lawn S, Pols R. Smoking bans in psychiatric inpatient settings? A review of the research. Aust N Z J Psychiatry. 2005;39(10):866-885.

17. Hempel AG, Kownacki R, Malin DH, et al. Effect of a total smoking ban in a maximum security psychiatric hospital. Behav Sci Law. 2002;20(5):507-522.

18. Harris GT, Parle D, Gagné J. Effects of a tobacco ban on long-term psychiatric patients. J Behav Health Serv Res. 2007;34(1):43-55.

19. Shmueli D, Fletcher L, Hall SE, et al. Changes in psychiatric patients’ thoughts about quitting smoking during a smoke-free hospitalization. Nicotine Tob Res. 2008;10(5):875-881.

20. Prochaska JJ, Fletcher L, Hall SE, et al. Return to smoking following a smoke-free psychiatric hospitalization. Am J Addict. 2006;15(1):15-22.

21. Marcus K. Smoking bans in long-term inpatient settings: a dilemma. Psychiatr Serv. 2008;59(3):330.-

22. Remal G. Hospital preparing to kick habit; A lawyer for smokers at Riverview Psychiatric Center sees little chance of reversing a smoking ban. Portland (Maine) Press Herald. December 29, 2006.

23. Arbogast v Peterson, 631 N.E.2d 673 (Ohio App 1993).

24. R (G) v Nottinghamshire Healthcare NHS Trust and others (2008).

25. Thiel v Nelson, 422 F.Supp. 2d 1024 (WD Wis 2006).

26. New Jersey Department of Health Services. Testimony of Kevin Martone, Assistant Commissioner, Department of Human Services, Division of Mental Health Services, New Jersey Assembly Human Services Committee, A-2308 Smoking Cessation, March 6, 2008. Trenton, NJ: New Jersey Department of Health Services. Available at: http://www.state.nj.us/humanservices/dmhs/Assembly_smoking_testimony_03_2008.pdf. Accessed February 14, 2009.

27. Helling v McKinney, 509 U.S. 25 (1993).

28. Appelbaum PS. Do hospitalized patients have a right to smoke? Psychiatr Serv. 1995;46(7):653-654, 660.

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Dear Dr. Mossman:

I work at a state mental hospital where all patients are adults who are court-committed, and at least 75% of them smoke. The hospital allows smoking in part of the only outdoor area where patients—smokers and nonsmokers—may go while in our most restrictive treatment phase. Patients come to us after spending at least 2 weeks in nonsmoking facilities where smokers receive nicotine replacement therapy. If patients want to smoke but have no money, in the past our hospital provided “unit cigarettes.”

In my state, a court commitment means the patient lacks the capacity to make decisions about psychiatric care. Of course nicotine is a psychoactive drug. If a patient starts smoking while in our care, would the hospital be liable for health-related expenses the patient may later incur?—Submitted by “Dr. A”

Speaking as one colleague to another about malpractice liability, letting psychiatric patients smoke is not breaching the standard of care toward smoking patients. But you care for nonsmoking patients as well, and other types of liability besides malpractice exist.

Doctors have moral duties for lots of things we can’t be sued for. Dr. A is right to be concerned. To explain, we’ll look at:

  • changes in attitudes about smoking
  • the link between smoking and mental illness
  • smoking bans in psychiatric facilities
  • malpractice potential
  • other issues Dr. A’s hospital should consider, such as offering patients assistance with smoking cessation.

Changing attitudes about smoking

Thirty years ago, doctors smoked during medical meetings, and smoking on airplanes and in public was commonplace. I worked at an adolescent inpatient unit, and line staff carried lighters. We thought lighting kids’ cigarettes was a legitimate way to establish rapport. Times and attitudes have changed. No hospital condones smoking these days, let alone smoking by minor patients. Since the Surgeon General first declared in 1964 that smoking was hazardous, U.S. adult smoking rates have dropped from 42% to under 20%.1

In the early 1990s, California issued the first statewide ban on smoking in work-places, including bars and restaurants.2 Nearly 3,000 state or local jurisdictions require workplaces and/or commercial establishments to be smoke-free.3 Recently, the legislature in Virginia—a major tobacco-producing state—voted to prohibit smoking in restaurants,4 and many other state governments are considering smoking bans. Smoking bans are intended to protect nonsmokers—especially children—from risks of secondhand smoke,5 but they also discourage individuals from taking up the habit6 and encourage smokers to quit.7

DO YOU HAVE A QUESTION ABOUT POSSIBLE LIABILITY?

  • Submit your malpractice-related questions to Dr. Mossman at douglas.mossman@dowdenhealth.com.
  • Include your name, address, and practice location. If your question is chosen for publication, your name can be withheld by request.
  • All readers who submit questions will be included in quarterly drawings for a $50 gift certificate for Professional Risk Management Services, Inc’s online marketplace of risk management publications and resources (www.prms.com).

Smoking and mental illness

Persons with serious psychiatric disorders have smoking rates 2 to 3 times higher than those of the general population.8,9 As Dr. A notes, nicotine is a psychoactive drug. Smoking may be a genuine—although ultimately unhealthy—form of self-medication and may have positive psychological effects, such as antidepressant activity for many mentally ill persons.10,11 The Joint Commission on Accreditation of Healthcare Organizations banned smoking in hospitals in 1992 but made an exception for psychiatric units. Out of sympathy for patients and concern about what could happen when they are deprived of a substance they intensely crave, many psychiatric wards continue to accommodate smokers.12

What some institutions have done

An increasing number of psychiatric facilities have instituted or are considering bans on smoking.13 The first psychiatric smoking bans were implemented despite fears that patient violence would increase and opposition from hospital employees—a group that often includes smokers. Experience shows that although not all smoking bans are successful or problem-free,14 they usually cause fewer problems than anticipated. We also know what factors help make smoke-free programs successful (Table).15

Table

Smoke-free plans that work: How to clear the air

• Take time—more than 6 months—to plan smoke-free initiatives
Supply patient and staff smokers with nicotine replacement therapy
Present clear, consistent, visible leadership
Encourage cohesive teamwork
Provide extensive education and training for staff
Reduce staff smoking rates
Offer programs and education to promote smoking cessation among staff members
Enforce nonsmoking policies
Source: Adapted from reference 15

Aggression, seclusion, discharges against medical advice, and “prn” medication use do not increase after smoking bans,5,16,17 and many patients experience health benefits.18 After discharge, however, most patients resume tobacco use.11,19,20

 

 

Smoking bans have been opposed on grounds that they abridge psychiatric patients’ rights and are unduly coercive.21,22 In the United States and United Kingdom, however, legal actions to block smoking bans have not succeeded, and courts have not recognized a fundamental “right to smoke.”23-25

Is allowing smoking malpractice?

Now that many psychiatric facilities have ended smoking, clinicians may worry—as does Dr. A—that we could incur malpractice liability if we let inpatients smoke. One of my University of Cincinnati law students, Amanda Smith, and I researched this topic and found no case report that said letting psychiatric inpatients smoke violated the standard of care.

This makes sense, because in the malpractice context, a practitioner is judged by what prudent, similarly situated physicians with similar training would do in similar circumstances. Many psychiatric facilities still permit smoking, so letting patients smoke does not breach the standard of care, even if it seems negligent.26

The ill effects of smoking accrue over years, not weeks or months. Almost all patients who smoke in hospitals also have smoked before hospitalization, and most smokers who are barred from smoking while inpatients resume soon after discharge. To succeed, a malpractice lawsuit must show that the defendant’s actions caused damages. A jury might find it hard to conclude that a permissive hospital smoking policy was the primary cause of a long-term smoker’s health problems.

4 other concerns

Nonsmokers’ rights. Arrangements at Dr. A’s hospital expose nonsmokers to secondhand cigarette smoke, which raises the possibility of legal action by nonsmokers. In 1993, the U.S. Supreme Court held that a prison inmate’s heavy exposure to secondhand smoke violated the Eighth Amendment ban on cruel and unusual punishment.27 Involuntary hospitalization is not punishment, but suits such as this might be brought on other grounds, such as violation of patients’ civil rights.28

Competence. In some states, civil commitment requires a finding that the respondent is not competent to make treatment decisions. Can persons who are not competent to make treatment decisions make good decisions about whether to smoke? Shouldn’t the hospital deal with patients’ nicotine dependence more therapeutically—and paternalistically—by providing nicotine replacement and encouraging smoking cessation? Shouldn’t the hospital also discourage patients who don’t smoke from starting?

Protecting patients. Dr. A’s hospital provides cigarettes to patients. Though compassion may be the motive, is the hospital failing to protect its incompetent patients and abetting their self-injurious behavior?

Helping smokers quit. Does the hospital offer treatment to help smokers quit? Although the problems that lead to civil commitment are immediate and serious, addressing long-term health issues is consistent with treating acute psychiatric crises. Many hospitals that permit smoking also encourage participation in smoking-cessation programs. Having these available to patients might make claims that the hospital failed in its duties to care for patients less plausible.

Related resources

Dear Dr. Mossman:

I work at a state mental hospital where all patients are adults who are court-committed, and at least 75% of them smoke. The hospital allows smoking in part of the only outdoor area where patients—smokers and nonsmokers—may go while in our most restrictive treatment phase. Patients come to us after spending at least 2 weeks in nonsmoking facilities where smokers receive nicotine replacement therapy. If patients want to smoke but have no money, in the past our hospital provided “unit cigarettes.”

In my state, a court commitment means the patient lacks the capacity to make decisions about psychiatric care. Of course nicotine is a psychoactive drug. If a patient starts smoking while in our care, would the hospital be liable for health-related expenses the patient may later incur?—Submitted by “Dr. A”

Speaking as one colleague to another about malpractice liability, letting psychiatric patients smoke is not breaching the standard of care toward smoking patients. But you care for nonsmoking patients as well, and other types of liability besides malpractice exist.

Doctors have moral duties for lots of things we can’t be sued for. Dr. A is right to be concerned. To explain, we’ll look at:

  • changes in attitudes about smoking
  • the link between smoking and mental illness
  • smoking bans in psychiatric facilities
  • malpractice potential
  • other issues Dr. A’s hospital should consider, such as offering patients assistance with smoking cessation.

Changing attitudes about smoking

Thirty years ago, doctors smoked during medical meetings, and smoking on airplanes and in public was commonplace. I worked at an adolescent inpatient unit, and line staff carried lighters. We thought lighting kids’ cigarettes was a legitimate way to establish rapport. Times and attitudes have changed. No hospital condones smoking these days, let alone smoking by minor patients. Since the Surgeon General first declared in 1964 that smoking was hazardous, U.S. adult smoking rates have dropped from 42% to under 20%.1

In the early 1990s, California issued the first statewide ban on smoking in work-places, including bars and restaurants.2 Nearly 3,000 state or local jurisdictions require workplaces and/or commercial establishments to be smoke-free.3 Recently, the legislature in Virginia—a major tobacco-producing state—voted to prohibit smoking in restaurants,4 and many other state governments are considering smoking bans. Smoking bans are intended to protect nonsmokers—especially children—from risks of secondhand smoke,5 but they also discourage individuals from taking up the habit6 and encourage smokers to quit.7

DO YOU HAVE A QUESTION ABOUT POSSIBLE LIABILITY?

  • Submit your malpractice-related questions to Dr. Mossman at douglas.mossman@dowdenhealth.com.
  • Include your name, address, and practice location. If your question is chosen for publication, your name can be withheld by request.
  • All readers who submit questions will be included in quarterly drawings for a $50 gift certificate for Professional Risk Management Services, Inc’s online marketplace of risk management publications and resources (www.prms.com).

Smoking and mental illness

Persons with serious psychiatric disorders have smoking rates 2 to 3 times higher than those of the general population.8,9 As Dr. A notes, nicotine is a psychoactive drug. Smoking may be a genuine—although ultimately unhealthy—form of self-medication and may have positive psychological effects, such as antidepressant activity for many mentally ill persons.10,11 The Joint Commission on Accreditation of Healthcare Organizations banned smoking in hospitals in 1992 but made an exception for psychiatric units. Out of sympathy for patients and concern about what could happen when they are deprived of a substance they intensely crave, many psychiatric wards continue to accommodate smokers.12

What some institutions have done

An increasing number of psychiatric facilities have instituted or are considering bans on smoking.13 The first psychiatric smoking bans were implemented despite fears that patient violence would increase and opposition from hospital employees—a group that often includes smokers. Experience shows that although not all smoking bans are successful or problem-free,14 they usually cause fewer problems than anticipated. We also know what factors help make smoke-free programs successful (Table).15

Table

Smoke-free plans that work: How to clear the air

• Take time—more than 6 months—to plan smoke-free initiatives
Supply patient and staff smokers with nicotine replacement therapy
Present clear, consistent, visible leadership
Encourage cohesive teamwork
Provide extensive education and training for staff
Reduce staff smoking rates
Offer programs and education to promote smoking cessation among staff members
Enforce nonsmoking policies
Source: Adapted from reference 15

Aggression, seclusion, discharges against medical advice, and “prn” medication use do not increase after smoking bans,5,16,17 and many patients experience health benefits.18 After discharge, however, most patients resume tobacco use.11,19,20

 

 

Smoking bans have been opposed on grounds that they abridge psychiatric patients’ rights and are unduly coercive.21,22 In the United States and United Kingdom, however, legal actions to block smoking bans have not succeeded, and courts have not recognized a fundamental “right to smoke.”23-25

Is allowing smoking malpractice?

Now that many psychiatric facilities have ended smoking, clinicians may worry—as does Dr. A—that we could incur malpractice liability if we let inpatients smoke. One of my University of Cincinnati law students, Amanda Smith, and I researched this topic and found no case report that said letting psychiatric inpatients smoke violated the standard of care.

This makes sense, because in the malpractice context, a practitioner is judged by what prudent, similarly situated physicians with similar training would do in similar circumstances. Many psychiatric facilities still permit smoking, so letting patients smoke does not breach the standard of care, even if it seems negligent.26

The ill effects of smoking accrue over years, not weeks or months. Almost all patients who smoke in hospitals also have smoked before hospitalization, and most smokers who are barred from smoking while inpatients resume soon after discharge. To succeed, a malpractice lawsuit must show that the defendant’s actions caused damages. A jury might find it hard to conclude that a permissive hospital smoking policy was the primary cause of a long-term smoker’s health problems.

4 other concerns

Nonsmokers’ rights. Arrangements at Dr. A’s hospital expose nonsmokers to secondhand cigarette smoke, which raises the possibility of legal action by nonsmokers. In 1993, the U.S. Supreme Court held that a prison inmate’s heavy exposure to secondhand smoke violated the Eighth Amendment ban on cruel and unusual punishment.27 Involuntary hospitalization is not punishment, but suits such as this might be brought on other grounds, such as violation of patients’ civil rights.28

Competence. In some states, civil commitment requires a finding that the respondent is not competent to make treatment decisions. Can persons who are not competent to make treatment decisions make good decisions about whether to smoke? Shouldn’t the hospital deal with patients’ nicotine dependence more therapeutically—and paternalistically—by providing nicotine replacement and encouraging smoking cessation? Shouldn’t the hospital also discourage patients who don’t smoke from starting?

Protecting patients. Dr. A’s hospital provides cigarettes to patients. Though compassion may be the motive, is the hospital failing to protect its incompetent patients and abetting their self-injurious behavior?

Helping smokers quit. Does the hospital offer treatment to help smokers quit? Although the problems that lead to civil commitment are immediate and serious, addressing long-term health issues is consistent with treating acute psychiatric crises. Many hospitals that permit smoking also encourage participation in smoking-cessation programs. Having these available to patients might make claims that the hospital failed in its duties to care for patients less plausible.

Related resources

References

1. Centers for Disease Control and Prevention. Cigarette smoking among adults—United States, 2007. Available at: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5745a2.htm. Accessed April 10, 2009.

2. Calif. Labor Code § 6404.5.

3. American Nonsmokers’ Rights Foundation. Overview list–how many smokefree laws? Available at: http://www.no-smoke.org/pdf/mediaordlist.pdf. Accessed February 11, 2009.

4. Kumar A. Va. House approves ban on smoking: most restaurants would be affected. Washington Post. February 10, 2009: Page A01.

5. U.S. Department of Health and Human Services. The health consequences of involuntary exposure to tobacco smoke: a report of the Surgeon General. Rockville, MD: U.S. Department of Health and Human Services; 2006.

6. Siegel M, Albers AB, Cheng DM, et al. Local restaurant smoking regulations and the adolescent smoking initiation process: results of a multilevel contextual analysis among Massachusetts youth. Arch Pediatr Adolesc Med. 2008;162(5):477-483.

7. Longo DR, Feldman MM, Kruse RL, et al. Implementing smoking bans in American hospitals: results of a national survey. Tob Control. 1998;7(1):47-55.

8. Lasser K, Boyd JW, Woolhandler S, et al. Smoking and mental illness: a population-based prevalence study. JAMA. 2000;284(20):2606-2610.

9. Morris CD, Giese AA, Turnbull JJ, et al. Predictors of tobacco use among persons with mental illnesses in a statewide population. Psychiatr Serv. 2006;57(7):1035-1038.

10. Cattapan-Ludewig K, Ludewig S, Jaquenoud Sirot E, et al. Why do schizophrenic patients smoke? Nervenarzt. 2005;76(3):287-294.

11. El-Guebaly N, Cathcart J, Currie S, et al. Public health and therapeutic aspects of smoking bans in mental health and addiction settings. Psychiatr Serv. 2002;53(12):1617-1622.

12. Williams JM. Eliminating tobacco use in mental health facilities: patients’ rights, public health, and policy issues. JAMA. 2008;299(5):571-573.

13. Parks J, Jewell P, eds,, Burke M. Technical report on smoking policy and treatment in state operated psychiatric facilities. Alexandria, VA: National Association of State Mental Health Program Directors Medical Directors Council; 2006. Technical Report 12.

14. Campion J, Lawn S, Brownlie A, et al. Implementing smoke-free policies in mental health inpatient units: learning from unsuccessful experience. Australas Psychiatry. 2008;16(2):92-97.

15. Lawn S, Campion J. Smoke-free initiatives in psychiatric inpatient units: a national survey of Australian sites. Adelaide, Australia: Flinders University; 2008.

16. Lawn S, Pols R. Smoking bans in psychiatric inpatient settings? A review of the research. Aust N Z J Psychiatry. 2005;39(10):866-885.

17. Hempel AG, Kownacki R, Malin DH, et al. Effect of a total smoking ban in a maximum security psychiatric hospital. Behav Sci Law. 2002;20(5):507-522.

18. Harris GT, Parle D, Gagné J. Effects of a tobacco ban on long-term psychiatric patients. J Behav Health Serv Res. 2007;34(1):43-55.

19. Shmueli D, Fletcher L, Hall SE, et al. Changes in psychiatric patients’ thoughts about quitting smoking during a smoke-free hospitalization. Nicotine Tob Res. 2008;10(5):875-881.

20. Prochaska JJ, Fletcher L, Hall SE, et al. Return to smoking following a smoke-free psychiatric hospitalization. Am J Addict. 2006;15(1):15-22.

21. Marcus K. Smoking bans in long-term inpatient settings: a dilemma. Psychiatr Serv. 2008;59(3):330.-

22. Remal G. Hospital preparing to kick habit; A lawyer for smokers at Riverview Psychiatric Center sees little chance of reversing a smoking ban. Portland (Maine) Press Herald. December 29, 2006.

23. Arbogast v Peterson, 631 N.E.2d 673 (Ohio App 1993).

24. R (G) v Nottinghamshire Healthcare NHS Trust and others (2008).

25. Thiel v Nelson, 422 F.Supp. 2d 1024 (WD Wis 2006).

26. New Jersey Department of Health Services. Testimony of Kevin Martone, Assistant Commissioner, Department of Human Services, Division of Mental Health Services, New Jersey Assembly Human Services Committee, A-2308 Smoking Cessation, March 6, 2008. Trenton, NJ: New Jersey Department of Health Services. Available at: http://www.state.nj.us/humanservices/dmhs/Assembly_smoking_testimony_03_2008.pdf. Accessed February 14, 2009.

27. Helling v McKinney, 509 U.S. 25 (1993).

28. Appelbaum PS. Do hospitalized patients have a right to smoke? Psychiatr Serv. 1995;46(7):653-654, 660.

References

1. Centers for Disease Control and Prevention. Cigarette smoking among adults—United States, 2007. Available at: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5745a2.htm. Accessed April 10, 2009.

2. Calif. Labor Code § 6404.5.

3. American Nonsmokers’ Rights Foundation. Overview list–how many smokefree laws? Available at: http://www.no-smoke.org/pdf/mediaordlist.pdf. Accessed February 11, 2009.

4. Kumar A. Va. House approves ban on smoking: most restaurants would be affected. Washington Post. February 10, 2009: Page A01.

5. U.S. Department of Health and Human Services. The health consequences of involuntary exposure to tobacco smoke: a report of the Surgeon General. Rockville, MD: U.S. Department of Health and Human Services; 2006.

6. Siegel M, Albers AB, Cheng DM, et al. Local restaurant smoking regulations and the adolescent smoking initiation process: results of a multilevel contextual analysis among Massachusetts youth. Arch Pediatr Adolesc Med. 2008;162(5):477-483.

7. Longo DR, Feldman MM, Kruse RL, et al. Implementing smoking bans in American hospitals: results of a national survey. Tob Control. 1998;7(1):47-55.

8. Lasser K, Boyd JW, Woolhandler S, et al. Smoking and mental illness: a population-based prevalence study. JAMA. 2000;284(20):2606-2610.

9. Morris CD, Giese AA, Turnbull JJ, et al. Predictors of tobacco use among persons with mental illnesses in a statewide population. Psychiatr Serv. 2006;57(7):1035-1038.

10. Cattapan-Ludewig K, Ludewig S, Jaquenoud Sirot E, et al. Why do schizophrenic patients smoke? Nervenarzt. 2005;76(3):287-294.

11. El-Guebaly N, Cathcart J, Currie S, et al. Public health and therapeutic aspects of smoking bans in mental health and addiction settings. Psychiatr Serv. 2002;53(12):1617-1622.

12. Williams JM. Eliminating tobacco use in mental health facilities: patients’ rights, public health, and policy issues. JAMA. 2008;299(5):571-573.

13. Parks J, Jewell P, eds,, Burke M. Technical report on smoking policy and treatment in state operated psychiatric facilities. Alexandria, VA: National Association of State Mental Health Program Directors Medical Directors Council; 2006. Technical Report 12.

14. Campion J, Lawn S, Brownlie A, et al. Implementing smoke-free policies in mental health inpatient units: learning from unsuccessful experience. Australas Psychiatry. 2008;16(2):92-97.

15. Lawn S, Campion J. Smoke-free initiatives in psychiatric inpatient units: a national survey of Australian sites. Adelaide, Australia: Flinders University; 2008.

16. Lawn S, Pols R. Smoking bans in psychiatric inpatient settings? A review of the research. Aust N Z J Psychiatry. 2005;39(10):866-885.

17. Hempel AG, Kownacki R, Malin DH, et al. Effect of a total smoking ban in a maximum security psychiatric hospital. Behav Sci Law. 2002;20(5):507-522.

18. Harris GT, Parle D, Gagné J. Effects of a tobacco ban on long-term psychiatric patients. J Behav Health Serv Res. 2007;34(1):43-55.

19. Shmueli D, Fletcher L, Hall SE, et al. Changes in psychiatric patients’ thoughts about quitting smoking during a smoke-free hospitalization. Nicotine Tob Res. 2008;10(5):875-881.

20. Prochaska JJ, Fletcher L, Hall SE, et al. Return to smoking following a smoke-free psychiatric hospitalization. Am J Addict. 2006;15(1):15-22.

21. Marcus K. Smoking bans in long-term inpatient settings: a dilemma. Psychiatr Serv. 2008;59(3):330.-

22. Remal G. Hospital preparing to kick habit; A lawyer for smokers at Riverview Psychiatric Center sees little chance of reversing a smoking ban. Portland (Maine) Press Herald. December 29, 2006.

23. Arbogast v Peterson, 631 N.E.2d 673 (Ohio App 1993).

24. R (G) v Nottinghamshire Healthcare NHS Trust and others (2008).

25. Thiel v Nelson, 422 F.Supp. 2d 1024 (WD Wis 2006).

26. New Jersey Department of Health Services. Testimony of Kevin Martone, Assistant Commissioner, Department of Human Services, Division of Mental Health Services, New Jersey Assembly Human Services Committee, A-2308 Smoking Cessation, March 6, 2008. Trenton, NJ: New Jersey Department of Health Services. Available at: http://www.state.nj.us/humanservices/dmhs/Assembly_smoking_testimony_03_2008.pdf. Accessed February 14, 2009.

27. Helling v McKinney, 509 U.S. 25 (1993).

28. Appelbaum PS. Do hospitalized patients have a right to smoke? Psychiatr Serv. 1995;46(7):653-654, 660.

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New Medicare Rule Reduces Retroactive Billing Period

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Medicare enrollment rules for retroactive billing implemented this month may catch some hospital medicine leaders by surprise—and cost them billing revenue.

The new rules from the Centers for Medicare and Medicaid Services (CMS), effective April 1, cut from 27 months to 30 days the window in which physicians can back-bill for services after successful enrollment or re-enrollment in Medicare. Most HM groups routinely allow new hospitalists to work prior to payor credentialing, then retroactively bill for those services once credentialing is completed, says Leslie Flores, MHA, a principal in Nelson/Flores Associates, an HM consulting firm in La Quinta, Calif., and director of SHM's Practice Management Institute.

Another provision of the rules states that practices must alert contractors of any changes in practice locations within 30 days, or risk expulsion from Medicare for as much as two years.

“This is likely to impact hospital medicine more than other specialties because of our rapid growth, the proportion of new graduates we hire, and the frequency with which hospitalists move around,” Flores says.

Marshall Maglothin, chief operating officer of Inpatient Specialists, which staffs 70 hospitalists at three Washington, D.C.-area hospitalists, suggests HM leaders read the new Medicare Provider Enrollment Toolkit, recently issued by the American Medical Association (AMA) and the Medical Group Management Association (MGMA). The resource includes an introduction to CMS’ Web-based version of the Provider Enrollment, Chain and Ownership System (PECOS), which became available this month for both HM groups and individual hospitalists. To download the toolkit, visit www.mgma.com.

“Until this gets worked over the next couple of months, there’s going to be a lot of missed revenue,” says Maglothin, who also runs HM advisory firm Blue Oak Consulting. “This is the ideal timeline, but it’s totally unrealistic when you’re dealing with over 600,000 physicians in the United States. There should have been an ease-in process.”

To help smooth the transition, CMS will hold a conference call to discuss provider issues at 2 p.m. (EST) Thursday. Capacity is limited, but to participate, call (800) 837-1935 and reference conference No. 94109369.

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Medicare enrollment rules for retroactive billing implemented this month may catch some hospital medicine leaders by surprise—and cost them billing revenue.

The new rules from the Centers for Medicare and Medicaid Services (CMS), effective April 1, cut from 27 months to 30 days the window in which physicians can back-bill for services after successful enrollment or re-enrollment in Medicare. Most HM groups routinely allow new hospitalists to work prior to payor credentialing, then retroactively bill for those services once credentialing is completed, says Leslie Flores, MHA, a principal in Nelson/Flores Associates, an HM consulting firm in La Quinta, Calif., and director of SHM's Practice Management Institute.

Another provision of the rules states that practices must alert contractors of any changes in practice locations within 30 days, or risk expulsion from Medicare for as much as two years.

“This is likely to impact hospital medicine more than other specialties because of our rapid growth, the proportion of new graduates we hire, and the frequency with which hospitalists move around,” Flores says.

Marshall Maglothin, chief operating officer of Inpatient Specialists, which staffs 70 hospitalists at three Washington, D.C.-area hospitalists, suggests HM leaders read the new Medicare Provider Enrollment Toolkit, recently issued by the American Medical Association (AMA) and the Medical Group Management Association (MGMA). The resource includes an introduction to CMS’ Web-based version of the Provider Enrollment, Chain and Ownership System (PECOS), which became available this month for both HM groups and individual hospitalists. To download the toolkit, visit www.mgma.com.

“Until this gets worked over the next couple of months, there’s going to be a lot of missed revenue,” says Maglothin, who also runs HM advisory firm Blue Oak Consulting. “This is the ideal timeline, but it’s totally unrealistic when you’re dealing with over 600,000 physicians in the United States. There should have been an ease-in process.”

To help smooth the transition, CMS will hold a conference call to discuss provider issues at 2 p.m. (EST) Thursday. Capacity is limited, but to participate, call (800) 837-1935 and reference conference No. 94109369.

Medicare enrollment rules for retroactive billing implemented this month may catch some hospital medicine leaders by surprise—and cost them billing revenue.

The new rules from the Centers for Medicare and Medicaid Services (CMS), effective April 1, cut from 27 months to 30 days the window in which physicians can back-bill for services after successful enrollment or re-enrollment in Medicare. Most HM groups routinely allow new hospitalists to work prior to payor credentialing, then retroactively bill for those services once credentialing is completed, says Leslie Flores, MHA, a principal in Nelson/Flores Associates, an HM consulting firm in La Quinta, Calif., and director of SHM's Practice Management Institute.

Another provision of the rules states that practices must alert contractors of any changes in practice locations within 30 days, or risk expulsion from Medicare for as much as two years.

“This is likely to impact hospital medicine more than other specialties because of our rapid growth, the proportion of new graduates we hire, and the frequency with which hospitalists move around,” Flores says.

Marshall Maglothin, chief operating officer of Inpatient Specialists, which staffs 70 hospitalists at three Washington, D.C.-area hospitalists, suggests HM leaders read the new Medicare Provider Enrollment Toolkit, recently issued by the American Medical Association (AMA) and the Medical Group Management Association (MGMA). The resource includes an introduction to CMS’ Web-based version of the Provider Enrollment, Chain and Ownership System (PECOS), which became available this month for both HM groups and individual hospitalists. To download the toolkit, visit www.mgma.com.

“Until this gets worked over the next couple of months, there’s going to be a lot of missed revenue,” says Maglothin, who also runs HM advisory firm Blue Oak Consulting. “This is the ideal timeline, but it’s totally unrealistic when you’re dealing with over 600,000 physicians in the United States. There should have been an ease-in process.”

To help smooth the transition, CMS will hold a conference call to discuss provider issues at 2 p.m. (EST) Thursday. Capacity is limited, but to participate, call (800) 837-1935 and reference conference No. 94109369.

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Now that more swine flu cases have been reported in New York City than in any other part of the U.S., local hospitalists are preparing to handle a potential influx of ill patients.

Dahlia Rizk, DO, FHM, director of the hospitalist program at Beth Israel Medical Center (BIMC) in New York City, says her 20-member team is receiving daily briefings from the hospital’s infection control expert. Hospitalists are learning about the latest confirmed cases and guidelines from the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO), and the NYC Department of Health and Mental Hygiene. Dr. Rizk is sharing the information with the rest of the hospital staff.

"This is our home; this is where we spend 90% of our day, if not 100%," Dr. Rizk says. “The staff know us, they rely on us, recognize us, and expect information and help from us when it comes to these kinds of situations."

John Novotny, MD, associate director of the hospitalist program at BIMC, says the hospital's strategy focuses on containing the virus and protecting other patients and staff from becoming infected by placing suspected swine flu patients in an isolation room that prevents the illness from being transmitted through droplets in the air. In addition, staff members will be expected to wear an N95 respirator facemask when entering the rooms of swine flu patients. Patients who are placed in the isolation room will be administered a PCR nasal swab test to confirm whether they are infected with influenza.

Dr. Rizk says patients showing mild to moderate symptoms will be asked to go home and remain there for seven days to reduce the chances of infecting others. “During this emergency, it is especially important to limit admissions of suspected influenza to those patients with more serious clinical conditions or significant comorbidities," she explains. "We need to focus on the priority of avoiding exposing other vulnerable inpatients to influenza, such as the elderly, the immune-compromised, or those with chronic heart and lung conditions.”

Drs. Novotny and Rizk suggest hospitalists follow these swine flu preparation tips:

  • Communicate. Keep nurses and other staff up to date about the latest treatment and containment guidelines.
  • Establish expectations. Be aware that staffers are looking to hospitalists for guidance during this emergency situation.
  • Monitor for updates. Stay informed through your infectious disease division, the CDC, the WHO, and your local public health department.

For more information, visit the CDC website.

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Now that more swine flu cases have been reported in New York City than in any other part of the U.S., local hospitalists are preparing to handle a potential influx of ill patients.

Dahlia Rizk, DO, FHM, director of the hospitalist program at Beth Israel Medical Center (BIMC) in New York City, says her 20-member team is receiving daily briefings from the hospital’s infection control expert. Hospitalists are learning about the latest confirmed cases and guidelines from the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO), and the NYC Department of Health and Mental Hygiene. Dr. Rizk is sharing the information with the rest of the hospital staff.

"This is our home; this is where we spend 90% of our day, if not 100%," Dr. Rizk says. “The staff know us, they rely on us, recognize us, and expect information and help from us when it comes to these kinds of situations."

John Novotny, MD, associate director of the hospitalist program at BIMC, says the hospital's strategy focuses on containing the virus and protecting other patients and staff from becoming infected by placing suspected swine flu patients in an isolation room that prevents the illness from being transmitted through droplets in the air. In addition, staff members will be expected to wear an N95 respirator facemask when entering the rooms of swine flu patients. Patients who are placed in the isolation room will be administered a PCR nasal swab test to confirm whether they are infected with influenza.

Dr. Rizk says patients showing mild to moderate symptoms will be asked to go home and remain there for seven days to reduce the chances of infecting others. “During this emergency, it is especially important to limit admissions of suspected influenza to those patients with more serious clinical conditions or significant comorbidities," she explains. "We need to focus on the priority of avoiding exposing other vulnerable inpatients to influenza, such as the elderly, the immune-compromised, or those with chronic heart and lung conditions.”

Drs. Novotny and Rizk suggest hospitalists follow these swine flu preparation tips:

  • Communicate. Keep nurses and other staff up to date about the latest treatment and containment guidelines.
  • Establish expectations. Be aware that staffers are looking to hospitalists for guidance during this emergency situation.
  • Monitor for updates. Stay informed through your infectious disease division, the CDC, the WHO, and your local public health department.

For more information, visit the CDC website.

Now that more swine flu cases have been reported in New York City than in any other part of the U.S., local hospitalists are preparing to handle a potential influx of ill patients.

Dahlia Rizk, DO, FHM, director of the hospitalist program at Beth Israel Medical Center (BIMC) in New York City, says her 20-member team is receiving daily briefings from the hospital’s infection control expert. Hospitalists are learning about the latest confirmed cases and guidelines from the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO), and the NYC Department of Health and Mental Hygiene. Dr. Rizk is sharing the information with the rest of the hospital staff.

"This is our home; this is where we spend 90% of our day, if not 100%," Dr. Rizk says. “The staff know us, they rely on us, recognize us, and expect information and help from us when it comes to these kinds of situations."

John Novotny, MD, associate director of the hospitalist program at BIMC, says the hospital's strategy focuses on containing the virus and protecting other patients and staff from becoming infected by placing suspected swine flu patients in an isolation room that prevents the illness from being transmitted through droplets in the air. In addition, staff members will be expected to wear an N95 respirator facemask when entering the rooms of swine flu patients. Patients who are placed in the isolation room will be administered a PCR nasal swab test to confirm whether they are infected with influenza.

Dr. Rizk says patients showing mild to moderate symptoms will be asked to go home and remain there for seven days to reduce the chances of infecting others. “During this emergency, it is especially important to limit admissions of suspected influenza to those patients with more serious clinical conditions or significant comorbidities," she explains. "We need to focus on the priority of avoiding exposing other vulnerable inpatients to influenza, such as the elderly, the immune-compromised, or those with chronic heart and lung conditions.”

Drs. Novotny and Rizk suggest hospitalists follow these swine flu preparation tips:

  • Communicate. Keep nurses and other staff up to date about the latest treatment and containment guidelines.
  • Establish expectations. Be aware that staffers are looking to hospitalists for guidance during this emergency situation.
  • Monitor for updates. Stay informed through your infectious disease division, the CDC, the WHO, and your local public health department.

For more information, visit the CDC website.

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In This Edition

Does a short duration of perioperative smoking cessation lead to a reduction in postoperative complications?

Background: Prior studies have demonstrated a reduction in postoperative complications when patients stop smoking in the perioperative period. However, they have not clearly shown what effect a fairly short duration of cessation, such as a period of only four weeks, has on the frequency of complications.

Study design: Randomized controlled trial.

Setting: Four university-affiliated hospitals in Sweden.

Synopsis: Using 117 patients who were daily smokers for less than one year between the ages of 18-79 who were scheduled for elective general or orthopedic surgery, this study showed that a smoking-cessation intervention initiated as little as four weeks prior to surgery resulted in fewer postoperative complications. The complication rate was reduced from 41% in the control group to 21% in the intervention group, which received cessation counseling and nicotine-replacement therapy. The relative risk reduction was 49% (95% confidence interval, 3-40) with a number needed to treat of five.

Because this was a randomized controlled trial with a large observed benefit, it appears to be reasonable to endorse perioperative smoking cessation as late as four weeks before an elective surgery. The study was limited in its ability to detect a difference in wound infections by the small sample size and the possibility patients might have unblinded themselves to outcome assessors, causing an overestimation of the effect of the intervention on the primary outcome of all complications.

Bottom line: Perioperative smoking cessation reduces postoperative complications even when started just four weeks prior to surgery.

Citation: Lindstrom D, Azodi OS, Wladis A, et al. Effects of a perioperative smoking cessation intervention on postoperative complications. Ann Surg. 2008;248(5):739-745.

Does implantable-defibrillator therapy cause deterioration in quality of life for patients with heart failure?

Background: Patients with depressed left-ventricular function are known to have improved survival after receiving implantable cardioverter defibrillators (ICDs). However, there is concern ICD therapy can prolong survival at the expense of a diminished quality of life.

Study design: Randomized placebo-controlled trial.

Setting: Multiple centers in the U.S., Canada, and New Zealand.

Synopsis: Using 2,479 patients from the Sudden Cardiac Death in Heart Failure trial who were 18 and older and had stable heart failure and depressed left-ventricular function, this study demonstrated no significant quality-of-life difference at 30 months when compared with patients who received ICD, amiodarone, and state-of-the-art medical therapy or an amiodarone placebo and state-of-the-art medical therapy. While functional status did not differ at any time between the three groups, psychological well-being was improved in the ICD group at three months (p=0.01) and 12 months (p=0.03) when compared with the placebo group, but at 30 months there was no difference between the groups.

While the trial was randomized and placebo-controlled, the investigators were unable to blind patients or outcome assessors. Nevertheless, the lack of deterioration of quality of life in ICD patients is reassuring.

 

 

Bottom line: Placement of ICDs in heart failure patients with a high risk of sudden cardiac death does not appear to decrease quality of life.

Citation: Mark DB, Anstrom KJ, Sun JL, et al. Quality of life with defibrillator therapy or amiodarone in heart failure. N Engl J Med. 2008;359:999-1008.

CLINICAL SHORTS

SERIAL 2-POINT ULTRASONOGRAPHY PLUS D-DIMER IS EQUIVALENT TO WHOLE-LEG ULTRASONOGRAPHY FOR DIAGNOSING DVT

Randomized trials show that when comparing serial 2-point ultrasonography plus D-dimer testing with whole-leg ultrasonography, the strategies were equivalent in excluding a first episode of suspected DVT in outpatients.

Citation: Bernardi E, Camporese G, Buller HR, et al. Serial 2-point ultrasonography plus D-dimer vs whole-leg color-coded Doppler ultrasonography for diagnosing suspected symptomatic deep vein thrombosis. JAMA. 2008;300(14):1653-1659.

DAILY HEMODIALYSIS IS COST-EFFECTIVE IN ICU PATIENTS WITH ACUTE KIDNEY INJURY (AKI)

Markov model based on prospective trial data shows daily hemodialysis is cost-effective for AKI in the ICU compared with alternate-day hemodialysis.

Citation: Desai AA, Baras J, Berk BB, et al. Management of acute kidney injury in the intensive care unit. Arch Intern Med. 2008;168(16):1761-1767.

THROMBOLYSIS FOR IN-HOSPITAL STROKE IS SAFE, BUT ASSOCIATED WITH DELAYS

Prospective observational trial shows thrombolysis is safe and effective for in-hospital stroke, but statistically significant delays exist compared with out-of-hospital strokes.

Citation: Masjuan J, Simal P, Fuentes B, et al. In-hospital stroke treated with intravenous tissue plasminogen activator. Stroke. 2008;39:2614-2616.

ALGORITHM CAN IDENTIFY HIGH-RISK HEART FAILURE PATIENTS

Prospective observational study identifies clinical variables for a bedside algorithm, which stratifies the risk of hospitalized heart failure patients for early mortality or readmission to identify those who might benefit from closer follow-up.

Citation: O’Connor CM, Abraham WT, Albert NM, et al. Predictors of mortality after discharge in patients hospitalized with heart failure: an analysis from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF). Am Heart J. 2008;156(4):662-673.

IN-HOSPITAL SMOKING-CESSATION INTERVENTIONS WITH FOLLOW-UP CAN WORK

Meta-analysis of 33 trials shows in-hospital smoking-cessation counseling followed up with more than one month of outpatient support can be effective.

Citation: Rigotti NA, Munafo MR, Stead LF. Smoking cessation interventions for hospitalized smokers. Arch Intern Med. 2008;168(18):1950-1960.

OMISSION OF KEY INFORMATION DURING SIGN-OUT LEADS TO ADVERSE CONSEQUENCES

An audio-taped study of sign-out among internal medicine house staff teams revealed omission of key information during sign-out resulted in delays in diagnosis or treatment.

Citation: Horwitz LI, Moin T, Krumholz HM, Wang L, Bradley EH. Consequences of inadequate sign-out for patient care. Arch Intern Med. 2008;168(16):1755-1760.

HOSPITAL PALLIATIVE CARE CONSULTATION TEAMS ARE ASSOCIATED WITH HOSPITAL COST SAVINGS

Analysis of administrative data from eight diverse hospitals with palliative-care programs revealed consultation with palliative care saved $1,696 (p<0.001) per hospital admission in patients discharged alive, and $4,098 (p=0.003) per hospital admission in patients who died in the hospital.

Citation: Morrison RS, Penrod JD, Cassel JB, et al. Cost savings associated with U.S. hospital palliative care consultation programs. Arch Intern Med. 2008;168(16):1783-1790.

HIGHER EDUCATIONAL DEBT INFLUENCES INTERNAL MEDICINE RESIDENT CAREER PLANS

U.S. medical graduates with a debt of $50,000 to $99,999 are more likely than those with no debt to choose a hospitalist career, and this preference increased with increased debt level.

Citation: McDonald FS, West CP, Popkave C, Kolars JC. Educational debt and reported career plans among internal medicine residents. Ann Intern Med. 2008;149:416-420.

BRAIN IMAGING IMPORTANT IN IDENTIFYING VASCULAR TERRITORY AFTER TIA OR MINOR STROKE

Neurologists were only moderately reliable at identifying the vascular territory of a TIA or motor stroke, highlighting the fact brain imaging is needed to accurately identify the vascular territories of these events.

Citation: Flossmann E, Redgrave JN, Briley D, Rothwell PM. Reliability of clinical diagnosis of the symptomatic vascular territory in patients with recent transient ischemic attack or minor stroke. Stroke. 2008;39:2457-2460.

HIGH-DOSE VITAMIN B SUPPLEMENTATION DOES NOT SLOW COGNITIVE DECLINE IN ALZHEIMER’S DISEASE

Multicenter, randomized, placebo-controlled trial finds no difference in the rate of cognitive decline in patients with Alzheimer’s disease treated with high-dose vitamin B supplements for 18 months.

Citation: Aisen PS, Schneider LS, Sano M, et al. High-dose B vitamin supplementation and cognitive decline in Alzheimer’s disease. JAMA. 2008; 300(15):1774-1783.

 

 

Can a simplified, revised Geneva score retain diagnostic accuracy and clinical utility?

Background: The revised Geneva score is a validated and objective clinical decision rule, but has multiple variables with different weights. This can make the tool cumbersome and difficult to remember, and could lead to inaccurate calculations and misjudgments in patient care.

Study design: Retrospective cohort study.

Setting: Four university-affiliated European hospitals.

Synopsis: Using data from two prior prospective trials involving patients with suspected pulmonary embolism (PE), this study showed re-analysis of these patients with a simplified, revised Geneva score, which gives only one point to each clinical factor, resulted in the same level of diagnostic accuracy. Specifically, data from 1,049 patients was used to construct a receiver-operating characteristic curve analysis comparing the standardized and simplified Geneva score, which showed areas under the curve of 0.75 (95% confidence interval 0.71-0.78) and 0.74 (0.70-0.77), respectively. Additionally, the safety of using this clinical tool to rule out PE was demonstrated when using both a three-level (low-intermediate probability) and a dichotomized scheme (PE unlikely) in combination with a negative D-dimer test.

The retrospective nature of the study was its major limitation. The authors suggest a prospective study to complete validation of the simplified, revised Geneva score.

Bottom line: With prospective analysis, it might be possible to further validate a simplified, revised Geneva score.

Citation: Klok FA, Mos ICM, Nijkeuter M, et al. Simplification of the revised Geneva score for assessing clinical probability of pulmonary embolism. Arch Intern Med. 2008;168(19):2131-2136.

Is the rate of postoperative major adverse cardiac events (MACEs) inversely related to time after percutaneous coronary intervention (PCI) with a drug-eluting stent (DES)?

Background: The American College of Cardiology and the American Heart Association recently released an advisory that included a recommendation to delay elective noncardiac surgery (NCS) for one year after DES placement. However, no large study addresses the timing of NCS after PCI with DES.

Study design: Retrospective observational study.

Setting: Mayo Clinic, Rochester, Minn.

Synopsis: Looking at 520 patients who had NCS after DES at the Mayo Clinic, 5.4% experienced MACEs, but the rate of MACEs was not significantly associated with the time after stent placement to surgery (p=0.337). However, observed rates of MACEs were lower after one year. Elderly patients and those going for emergent surgery are at the highest risk for MACE. Bleeding complications were not associated with antiplatelet use.

Although this study does not provide a clear cutoff time for when it is safe to proceed to NCS after DES, it is somewhat reassuring to see the relatively small number of MACEs and the lack of bleeding complications associated with antiplatelet use. However, careful coordination between hospitalists, cardiologists, anesthesiologists, and surgeons is still needed when coordinating NCS after DES, especially in the elderly or during emergent situations.

Bottom line: While time to noncardiac surgery after drug-eluting stent placement is not associated with major adverse cardiac events, observed rates of events are lower after one year.

Citation: Rabbitts JA, Nuttall GA, Brown MJ, et al. Cardiac risk of non-cardiac surgery after percutaneous coronary intervention with drug-eluting stents. Anesthesiology.2008;109: 596-604.

Is the risk of MACEs and bleeding events for patients undergoing NCS related to the time interval between PCI with bare-metal stent?

Background: In order to prevent thrombosis of bare-metal stents (BMS) placed during percutaneous coronary intervention (PCI), antiplatelet therapy is used. This poses a risk of bleeding, if surgery is needed during the antiplatelet therapy. The American College of Cardiology and the American Heart Association recommends delaying NCS for at least six weeks after PCI with BMS.

 

 

Study design: Retrospective observational study.

Setting: Mayo Clinic, Rochester, Minn.

Synopsis: Looking at 899 patients who had NCS within one year of PCI with BMS at the Mayo Clinic between Jan. 1, 1990, and Jan. 1, 2005, this study found that when NCS was done 30 days or less after PCI with BMS, the MACEs rate was 10.5%, compared with 2.8% when NCS was done 91 or more days after PCI with BMS. After a multivariable analysis, it also was shown bleeding events were not associated with time between PCI with BMS and NCS.

While the American College of Cardiology and the American Heart Association recommends delaying NCS for at least six weeks after PCI with BMS, waiting at least 90 days would permit completion of antiplatelet therapy and re-endothelialization of the stent.

Bottom line: The risk of MACEs with noncardiac surgery is lowest when performed at least 90 days after PCI with bare-metal stent.

Citation: Nuttall GA, Brown MJ, Stombaugh JW, et al. Time and cardiac risk of surgery after bare-metal stent, percutaneous coronary intervention. Anesthesiology. 2008;109: 588-595.

Should we screen extensively for cancer in patients with newly diagnosed venous thromboembolism (VTE)?

Background: It is well known VTE can be the first manifestation of previously undiagnosed cancer. Retrospective studies have suggested “limited” cancer screening, including a history and physical examination, along with basic blood work, adequately identifies malignancy in patients with unexplained VTE. However, more recent prospective studies have suggested more extensive screening, which includes imaging studies or tumor-marker measurement, can increase the rate of cancer detection.

Study design: Systematic review.

Setting: Literature search using MEDLINE, EMBASE, the Cochrane Register of Controlled Trials, and evidence-based medicine reviews.

Synopsis: Thirty-six studies of 9,516 patients with VTE reported the period prevalence of previously undiagnosed cancer from baseline to 12 months was 6.3% (95% confidence interval (CI) of 5.6% to 6.9%) in all patients with VTE, and was even higher in patients with unprovoked VTE, 10% (95% CI 8.6% to 11.3%). Of the 34 articles used for prevalence assessment, an extensive screening strategy using CT scans of the abdomen and pelvis increased the proportion of previously undiagnosed cancer detection from 49.4% (CI, 40.2% to 58.5%; limited screening) to 69.7% (CI, 61.1% to 77.8%) in patients with unprovoked VTE. Ultrasonography of the abdomen and pelvis and tumor-marker screening did not result in a clinically significant increase in the frequency of cancer detection.

Four studies compared the rate of detection of early-stage, previously undiagnosed cancer between the limited and extensive screening strategies. Extensive screening led to an absolute decrease in cancer-related mortality of 1.9%, but this difference was not statistically significant.

In this systematic review, there is a great deal of heterogeneity in the studies. Most of the studies did not look at whether an increase in detection of new malignant conditions resulted in a change in the detection rate of early-stage cancer, or a decrease in cancer-related morbidity, cancer-related mortality, or overall mortality. Furthermore, the studies did not assess the consequences of extensive screening, such as patient anxiety and discomfort, testing complications, burden of additional tests for false-positive results, or cost-effectiveness. However, it is important for hospitalists to recognize undiagnosed cancer is common in unexplained VTE and warrants at least a limited-screening approach with more extensive screening.

Bottom line: Although the prevalence of undiagnosed cancer is common in VTE, extensive screening did not offer a cancer-related mortality benefit. CT of the abdomen and pelvis did, however, lead to a greater number of cancer diagnoses in patients with unexplained VTE.

 

 

Citation: Carrier M, Le Gal G, Wells PS, Fergusson D, Ramsay T, Rodger MA. Systematic review: the Trousseau syndrome revisited: should we screen extensively for cancer in patients with venous thromboembolism? Ann Intern Med. 2008;149: 323-333.

Does the use of preadmission statins decrease the risk of death, bacteremia, and pulmonary complications in patients admitted with pneumonia?

Background: Both experimental and clinical studies have suggested statins improve outcomes in severe infections, such as sepsis. This is thought to be due to the antithrombotic, anti-inflammatory, and immunomodulatory effects of statins. However, previous studies on the effect of statins on pneumonia have conflicting outcomes.

Study design: Population-based cohort study of 29,900 patients.

Setting: Danish Health Registry.

Synopsis: Researchers studied patients ages 15 years and older hospitalized with pneumonia for the first time between January 1997 and December 2004. While statin users had more co-morbidities than nonusers, the 30-day mortality was 10.3% in users, compared with 15.7% in nonusers, corresponding to an adjusted 30-day mortality rate ratio of 0.69 (95% CI of 0.58-0.82). The 90-day mortality ratio was 16.8% in users, compared with 22.4% in nonusers, corresponding to an adjusted 90-day mortality ratio of 0.75 (95% CI of 0.65-0.86). Former use of statins was not associated with a decreased risk of death. The adjusted risk for bacteremia and pulmonary complications was not significantly different between nonusers and users.

Because this was an observational study, a causal relationship cannot be determined. Hospitalists should be alerted to the possibility statins might, in the future, prove to be a standard treatment modality in pneumonia. A randomized, double-blind trial might help further determine the effect of the acute use of statins on pneumonia outcomes.

Bottom line: Preadmission statin use is associated with a decrease in 30- and 90-day mortality in pneumonia.

Citation: Thomsen RW, Riis A, Kornum JB, Christensen S, Johnsen SP, Sorensen HT. Preadmission use of statins and outcomes after hospitalization with pneumonia. Arch Intern Med. 2008;168(19):2081-2087.

Do outcomes differ when patients with acute myocardial infarction (MI) undergo PCI with drug-eluting stents (DES) compared with bare-metal stents?

Background: Randomized trials comparing drug-eluting stents with bare-metal stents in acute MI have been limited in size and duration. Concern exists regarding higher mortality among patients with ST-elevation MI treated with DES.

Study design: Observational, cohort study.

Setting: Patients were identified from a state-mandated database, in which all PCI performed in Massachusetts are reported.

Synopsis: Between April 2003 and September 2004, 7,217 eligible patients underwent stenting for acute MI. They were assigned to either the DES group or the bare-metal stent (BMS) group using propensity score matching. Patients in the DES group had lower mortality at two years, compared to a matched cohort of patients in the BMS group with MI (10.7% vs. 12.8%; absolute risk difference, -2.1%, CI, -3.8% to -0.4%). A statistically significant difference was noted among patients with or without ST-elevation MI.

The rates of target vessel revascularization at two years with MI were significantly lower among patients receiving DES than among those receiving BMS (9.6% vs. 14.5%; risk difference, -4.9%; CI, -6.1% to -3.1%).

The study is limited by its observational nature and residual confounding bias after matching. Importantly, this study was performed to determine if DESs were harmful, and the finding of reduced mortality was unanticipated.

Bottom line: Although patients with acute MI treated with drug-eluting stents had lower mortality and repeat revascularization rates compared with bare-metal stents, this outcome merits confirmation in randomized trials.

Citation: Mauri L, Silbaugh TS, Garg P, et al. Drug-eluting or bare-metal stents for acute myocardial infarction. N Engl J Med. 2008;359 (13):1330-1342.

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The Hospitalist - 2009(04)
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In This Edition

Does a short duration of perioperative smoking cessation lead to a reduction in postoperative complications?

Background: Prior studies have demonstrated a reduction in postoperative complications when patients stop smoking in the perioperative period. However, they have not clearly shown what effect a fairly short duration of cessation, such as a period of only four weeks, has on the frequency of complications.

Study design: Randomized controlled trial.

Setting: Four university-affiliated hospitals in Sweden.

Synopsis: Using 117 patients who were daily smokers for less than one year between the ages of 18-79 who were scheduled for elective general or orthopedic surgery, this study showed that a smoking-cessation intervention initiated as little as four weeks prior to surgery resulted in fewer postoperative complications. The complication rate was reduced from 41% in the control group to 21% in the intervention group, which received cessation counseling and nicotine-replacement therapy. The relative risk reduction was 49% (95% confidence interval, 3-40) with a number needed to treat of five.

Because this was a randomized controlled trial with a large observed benefit, it appears to be reasonable to endorse perioperative smoking cessation as late as four weeks before an elective surgery. The study was limited in its ability to detect a difference in wound infections by the small sample size and the possibility patients might have unblinded themselves to outcome assessors, causing an overestimation of the effect of the intervention on the primary outcome of all complications.

Bottom line: Perioperative smoking cessation reduces postoperative complications even when started just four weeks prior to surgery.

Citation: Lindstrom D, Azodi OS, Wladis A, et al. Effects of a perioperative smoking cessation intervention on postoperative complications. Ann Surg. 2008;248(5):739-745.

Does implantable-defibrillator therapy cause deterioration in quality of life for patients with heart failure?

Background: Patients with depressed left-ventricular function are known to have improved survival after receiving implantable cardioverter defibrillators (ICDs). However, there is concern ICD therapy can prolong survival at the expense of a diminished quality of life.

Study design: Randomized placebo-controlled trial.

Setting: Multiple centers in the U.S., Canada, and New Zealand.

Synopsis: Using 2,479 patients from the Sudden Cardiac Death in Heart Failure trial who were 18 and older and had stable heart failure and depressed left-ventricular function, this study demonstrated no significant quality-of-life difference at 30 months when compared with patients who received ICD, amiodarone, and state-of-the-art medical therapy or an amiodarone placebo and state-of-the-art medical therapy. While functional status did not differ at any time between the three groups, psychological well-being was improved in the ICD group at three months (p=0.01) and 12 months (p=0.03) when compared with the placebo group, but at 30 months there was no difference between the groups.

While the trial was randomized and placebo-controlled, the investigators were unable to blind patients or outcome assessors. Nevertheless, the lack of deterioration of quality of life in ICD patients is reassuring.

 

 

Bottom line: Placement of ICDs in heart failure patients with a high risk of sudden cardiac death does not appear to decrease quality of life.

Citation: Mark DB, Anstrom KJ, Sun JL, et al. Quality of life with defibrillator therapy or amiodarone in heart failure. N Engl J Med. 2008;359:999-1008.

CLINICAL SHORTS

SERIAL 2-POINT ULTRASONOGRAPHY PLUS D-DIMER IS EQUIVALENT TO WHOLE-LEG ULTRASONOGRAPHY FOR DIAGNOSING DVT

Randomized trials show that when comparing serial 2-point ultrasonography plus D-dimer testing with whole-leg ultrasonography, the strategies were equivalent in excluding a first episode of suspected DVT in outpatients.

Citation: Bernardi E, Camporese G, Buller HR, et al. Serial 2-point ultrasonography plus D-dimer vs whole-leg color-coded Doppler ultrasonography for diagnosing suspected symptomatic deep vein thrombosis. JAMA. 2008;300(14):1653-1659.

DAILY HEMODIALYSIS IS COST-EFFECTIVE IN ICU PATIENTS WITH ACUTE KIDNEY INJURY (AKI)

Markov model based on prospective trial data shows daily hemodialysis is cost-effective for AKI in the ICU compared with alternate-day hemodialysis.

Citation: Desai AA, Baras J, Berk BB, et al. Management of acute kidney injury in the intensive care unit. Arch Intern Med. 2008;168(16):1761-1767.

THROMBOLYSIS FOR IN-HOSPITAL STROKE IS SAFE, BUT ASSOCIATED WITH DELAYS

Prospective observational trial shows thrombolysis is safe and effective for in-hospital stroke, but statistically significant delays exist compared with out-of-hospital strokes.

Citation: Masjuan J, Simal P, Fuentes B, et al. In-hospital stroke treated with intravenous tissue plasminogen activator. Stroke. 2008;39:2614-2616.

ALGORITHM CAN IDENTIFY HIGH-RISK HEART FAILURE PATIENTS

Prospective observational study identifies clinical variables for a bedside algorithm, which stratifies the risk of hospitalized heart failure patients for early mortality or readmission to identify those who might benefit from closer follow-up.

Citation: O’Connor CM, Abraham WT, Albert NM, et al. Predictors of mortality after discharge in patients hospitalized with heart failure: an analysis from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF). Am Heart J. 2008;156(4):662-673.

IN-HOSPITAL SMOKING-CESSATION INTERVENTIONS WITH FOLLOW-UP CAN WORK

Meta-analysis of 33 trials shows in-hospital smoking-cessation counseling followed up with more than one month of outpatient support can be effective.

Citation: Rigotti NA, Munafo MR, Stead LF. Smoking cessation interventions for hospitalized smokers. Arch Intern Med. 2008;168(18):1950-1960.

OMISSION OF KEY INFORMATION DURING SIGN-OUT LEADS TO ADVERSE CONSEQUENCES

An audio-taped study of sign-out among internal medicine house staff teams revealed omission of key information during sign-out resulted in delays in diagnosis or treatment.

Citation: Horwitz LI, Moin T, Krumholz HM, Wang L, Bradley EH. Consequences of inadequate sign-out for patient care. Arch Intern Med. 2008;168(16):1755-1760.

HOSPITAL PALLIATIVE CARE CONSULTATION TEAMS ARE ASSOCIATED WITH HOSPITAL COST SAVINGS

Analysis of administrative data from eight diverse hospitals with palliative-care programs revealed consultation with palliative care saved $1,696 (p<0.001) per hospital admission in patients discharged alive, and $4,098 (p=0.003) per hospital admission in patients who died in the hospital.

Citation: Morrison RS, Penrod JD, Cassel JB, et al. Cost savings associated with U.S. hospital palliative care consultation programs. Arch Intern Med. 2008;168(16):1783-1790.

HIGHER EDUCATIONAL DEBT INFLUENCES INTERNAL MEDICINE RESIDENT CAREER PLANS

U.S. medical graduates with a debt of $50,000 to $99,999 are more likely than those with no debt to choose a hospitalist career, and this preference increased with increased debt level.

Citation: McDonald FS, West CP, Popkave C, Kolars JC. Educational debt and reported career plans among internal medicine residents. Ann Intern Med. 2008;149:416-420.

BRAIN IMAGING IMPORTANT IN IDENTIFYING VASCULAR TERRITORY AFTER TIA OR MINOR STROKE

Neurologists were only moderately reliable at identifying the vascular territory of a TIA or motor stroke, highlighting the fact brain imaging is needed to accurately identify the vascular territories of these events.

Citation: Flossmann E, Redgrave JN, Briley D, Rothwell PM. Reliability of clinical diagnosis of the symptomatic vascular territory in patients with recent transient ischemic attack or minor stroke. Stroke. 2008;39:2457-2460.

HIGH-DOSE VITAMIN B SUPPLEMENTATION DOES NOT SLOW COGNITIVE DECLINE IN ALZHEIMER’S DISEASE

Multicenter, randomized, placebo-controlled trial finds no difference in the rate of cognitive decline in patients with Alzheimer’s disease treated with high-dose vitamin B supplements for 18 months.

Citation: Aisen PS, Schneider LS, Sano M, et al. High-dose B vitamin supplementation and cognitive decline in Alzheimer’s disease. JAMA. 2008; 300(15):1774-1783.

 

 

Can a simplified, revised Geneva score retain diagnostic accuracy and clinical utility?

Background: The revised Geneva score is a validated and objective clinical decision rule, but has multiple variables with different weights. This can make the tool cumbersome and difficult to remember, and could lead to inaccurate calculations and misjudgments in patient care.

Study design: Retrospective cohort study.

Setting: Four university-affiliated European hospitals.

Synopsis: Using data from two prior prospective trials involving patients with suspected pulmonary embolism (PE), this study showed re-analysis of these patients with a simplified, revised Geneva score, which gives only one point to each clinical factor, resulted in the same level of diagnostic accuracy. Specifically, data from 1,049 patients was used to construct a receiver-operating characteristic curve analysis comparing the standardized and simplified Geneva score, which showed areas under the curve of 0.75 (95% confidence interval 0.71-0.78) and 0.74 (0.70-0.77), respectively. Additionally, the safety of using this clinical tool to rule out PE was demonstrated when using both a three-level (low-intermediate probability) and a dichotomized scheme (PE unlikely) in combination with a negative D-dimer test.

The retrospective nature of the study was its major limitation. The authors suggest a prospective study to complete validation of the simplified, revised Geneva score.

Bottom line: With prospective analysis, it might be possible to further validate a simplified, revised Geneva score.

Citation: Klok FA, Mos ICM, Nijkeuter M, et al. Simplification of the revised Geneva score for assessing clinical probability of pulmonary embolism. Arch Intern Med. 2008;168(19):2131-2136.

Is the rate of postoperative major adverse cardiac events (MACEs) inversely related to time after percutaneous coronary intervention (PCI) with a drug-eluting stent (DES)?

Background: The American College of Cardiology and the American Heart Association recently released an advisory that included a recommendation to delay elective noncardiac surgery (NCS) for one year after DES placement. However, no large study addresses the timing of NCS after PCI with DES.

Study design: Retrospective observational study.

Setting: Mayo Clinic, Rochester, Minn.

Synopsis: Looking at 520 patients who had NCS after DES at the Mayo Clinic, 5.4% experienced MACEs, but the rate of MACEs was not significantly associated with the time after stent placement to surgery (p=0.337). However, observed rates of MACEs were lower after one year. Elderly patients and those going for emergent surgery are at the highest risk for MACE. Bleeding complications were not associated with antiplatelet use.

Although this study does not provide a clear cutoff time for when it is safe to proceed to NCS after DES, it is somewhat reassuring to see the relatively small number of MACEs and the lack of bleeding complications associated with antiplatelet use. However, careful coordination between hospitalists, cardiologists, anesthesiologists, and surgeons is still needed when coordinating NCS after DES, especially in the elderly or during emergent situations.

Bottom line: While time to noncardiac surgery after drug-eluting stent placement is not associated with major adverse cardiac events, observed rates of events are lower after one year.

Citation: Rabbitts JA, Nuttall GA, Brown MJ, et al. Cardiac risk of non-cardiac surgery after percutaneous coronary intervention with drug-eluting stents. Anesthesiology.2008;109: 596-604.

Is the risk of MACEs and bleeding events for patients undergoing NCS related to the time interval between PCI with bare-metal stent?

Background: In order to prevent thrombosis of bare-metal stents (BMS) placed during percutaneous coronary intervention (PCI), antiplatelet therapy is used. This poses a risk of bleeding, if surgery is needed during the antiplatelet therapy. The American College of Cardiology and the American Heart Association recommends delaying NCS for at least six weeks after PCI with BMS.

 

 

Study design: Retrospective observational study.

Setting: Mayo Clinic, Rochester, Minn.

Synopsis: Looking at 899 patients who had NCS within one year of PCI with BMS at the Mayo Clinic between Jan. 1, 1990, and Jan. 1, 2005, this study found that when NCS was done 30 days or less after PCI with BMS, the MACEs rate was 10.5%, compared with 2.8% when NCS was done 91 or more days after PCI with BMS. After a multivariable analysis, it also was shown bleeding events were not associated with time between PCI with BMS and NCS.

While the American College of Cardiology and the American Heart Association recommends delaying NCS for at least six weeks after PCI with BMS, waiting at least 90 days would permit completion of antiplatelet therapy and re-endothelialization of the stent.

Bottom line: The risk of MACEs with noncardiac surgery is lowest when performed at least 90 days after PCI with bare-metal stent.

Citation: Nuttall GA, Brown MJ, Stombaugh JW, et al. Time and cardiac risk of surgery after bare-metal stent, percutaneous coronary intervention. Anesthesiology. 2008;109: 588-595.

Should we screen extensively for cancer in patients with newly diagnosed venous thromboembolism (VTE)?

Background: It is well known VTE can be the first manifestation of previously undiagnosed cancer. Retrospective studies have suggested “limited” cancer screening, including a history and physical examination, along with basic blood work, adequately identifies malignancy in patients with unexplained VTE. However, more recent prospective studies have suggested more extensive screening, which includes imaging studies or tumor-marker measurement, can increase the rate of cancer detection.

Study design: Systematic review.

Setting: Literature search using MEDLINE, EMBASE, the Cochrane Register of Controlled Trials, and evidence-based medicine reviews.

Synopsis: Thirty-six studies of 9,516 patients with VTE reported the period prevalence of previously undiagnosed cancer from baseline to 12 months was 6.3% (95% confidence interval (CI) of 5.6% to 6.9%) in all patients with VTE, and was even higher in patients with unprovoked VTE, 10% (95% CI 8.6% to 11.3%). Of the 34 articles used for prevalence assessment, an extensive screening strategy using CT scans of the abdomen and pelvis increased the proportion of previously undiagnosed cancer detection from 49.4% (CI, 40.2% to 58.5%; limited screening) to 69.7% (CI, 61.1% to 77.8%) in patients with unprovoked VTE. Ultrasonography of the abdomen and pelvis and tumor-marker screening did not result in a clinically significant increase in the frequency of cancer detection.

Four studies compared the rate of detection of early-stage, previously undiagnosed cancer between the limited and extensive screening strategies. Extensive screening led to an absolute decrease in cancer-related mortality of 1.9%, but this difference was not statistically significant.

In this systematic review, there is a great deal of heterogeneity in the studies. Most of the studies did not look at whether an increase in detection of new malignant conditions resulted in a change in the detection rate of early-stage cancer, or a decrease in cancer-related morbidity, cancer-related mortality, or overall mortality. Furthermore, the studies did not assess the consequences of extensive screening, such as patient anxiety and discomfort, testing complications, burden of additional tests for false-positive results, or cost-effectiveness. However, it is important for hospitalists to recognize undiagnosed cancer is common in unexplained VTE and warrants at least a limited-screening approach with more extensive screening.

Bottom line: Although the prevalence of undiagnosed cancer is common in VTE, extensive screening did not offer a cancer-related mortality benefit. CT of the abdomen and pelvis did, however, lead to a greater number of cancer diagnoses in patients with unexplained VTE.

 

 

Citation: Carrier M, Le Gal G, Wells PS, Fergusson D, Ramsay T, Rodger MA. Systematic review: the Trousseau syndrome revisited: should we screen extensively for cancer in patients with venous thromboembolism? Ann Intern Med. 2008;149: 323-333.

Does the use of preadmission statins decrease the risk of death, bacteremia, and pulmonary complications in patients admitted with pneumonia?

Background: Both experimental and clinical studies have suggested statins improve outcomes in severe infections, such as sepsis. This is thought to be due to the antithrombotic, anti-inflammatory, and immunomodulatory effects of statins. However, previous studies on the effect of statins on pneumonia have conflicting outcomes.

Study design: Population-based cohort study of 29,900 patients.

Setting: Danish Health Registry.

Synopsis: Researchers studied patients ages 15 years and older hospitalized with pneumonia for the first time between January 1997 and December 2004. While statin users had more co-morbidities than nonusers, the 30-day mortality was 10.3% in users, compared with 15.7% in nonusers, corresponding to an adjusted 30-day mortality rate ratio of 0.69 (95% CI of 0.58-0.82). The 90-day mortality ratio was 16.8% in users, compared with 22.4% in nonusers, corresponding to an adjusted 90-day mortality ratio of 0.75 (95% CI of 0.65-0.86). Former use of statins was not associated with a decreased risk of death. The adjusted risk for bacteremia and pulmonary complications was not significantly different between nonusers and users.

Because this was an observational study, a causal relationship cannot be determined. Hospitalists should be alerted to the possibility statins might, in the future, prove to be a standard treatment modality in pneumonia. A randomized, double-blind trial might help further determine the effect of the acute use of statins on pneumonia outcomes.

Bottom line: Preadmission statin use is associated with a decrease in 30- and 90-day mortality in pneumonia.

Citation: Thomsen RW, Riis A, Kornum JB, Christensen S, Johnsen SP, Sorensen HT. Preadmission use of statins and outcomes after hospitalization with pneumonia. Arch Intern Med. 2008;168(19):2081-2087.

Do outcomes differ when patients with acute myocardial infarction (MI) undergo PCI with drug-eluting stents (DES) compared with bare-metal stents?

Background: Randomized trials comparing drug-eluting stents with bare-metal stents in acute MI have been limited in size and duration. Concern exists regarding higher mortality among patients with ST-elevation MI treated with DES.

Study design: Observational, cohort study.

Setting: Patients were identified from a state-mandated database, in which all PCI performed in Massachusetts are reported.

Synopsis: Between April 2003 and September 2004, 7,217 eligible patients underwent stenting for acute MI. They were assigned to either the DES group or the bare-metal stent (BMS) group using propensity score matching. Patients in the DES group had lower mortality at two years, compared to a matched cohort of patients in the BMS group with MI (10.7% vs. 12.8%; absolute risk difference, -2.1%, CI, -3.8% to -0.4%). A statistically significant difference was noted among patients with or without ST-elevation MI.

The rates of target vessel revascularization at two years with MI were significantly lower among patients receiving DES than among those receiving BMS (9.6% vs. 14.5%; risk difference, -4.9%; CI, -6.1% to -3.1%).

The study is limited by its observational nature and residual confounding bias after matching. Importantly, this study was performed to determine if DESs were harmful, and the finding of reduced mortality was unanticipated.

Bottom line: Although patients with acute MI treated with drug-eluting stents had lower mortality and repeat revascularization rates compared with bare-metal stents, this outcome merits confirmation in randomized trials.

Citation: Mauri L, Silbaugh TS, Garg P, et al. Drug-eluting or bare-metal stents for acute myocardial infarction. N Engl J Med. 2008;359 (13):1330-1342.

In This Edition

Does a short duration of perioperative smoking cessation lead to a reduction in postoperative complications?

Background: Prior studies have demonstrated a reduction in postoperative complications when patients stop smoking in the perioperative period. However, they have not clearly shown what effect a fairly short duration of cessation, such as a period of only four weeks, has on the frequency of complications.

Study design: Randomized controlled trial.

Setting: Four university-affiliated hospitals in Sweden.

Synopsis: Using 117 patients who were daily smokers for less than one year between the ages of 18-79 who were scheduled for elective general or orthopedic surgery, this study showed that a smoking-cessation intervention initiated as little as four weeks prior to surgery resulted in fewer postoperative complications. The complication rate was reduced from 41% in the control group to 21% in the intervention group, which received cessation counseling and nicotine-replacement therapy. The relative risk reduction was 49% (95% confidence interval, 3-40) with a number needed to treat of five.

Because this was a randomized controlled trial with a large observed benefit, it appears to be reasonable to endorse perioperative smoking cessation as late as four weeks before an elective surgery. The study was limited in its ability to detect a difference in wound infections by the small sample size and the possibility patients might have unblinded themselves to outcome assessors, causing an overestimation of the effect of the intervention on the primary outcome of all complications.

Bottom line: Perioperative smoking cessation reduces postoperative complications even when started just four weeks prior to surgery.

Citation: Lindstrom D, Azodi OS, Wladis A, et al. Effects of a perioperative smoking cessation intervention on postoperative complications. Ann Surg. 2008;248(5):739-745.

Does implantable-defibrillator therapy cause deterioration in quality of life for patients with heart failure?

Background: Patients with depressed left-ventricular function are known to have improved survival after receiving implantable cardioverter defibrillators (ICDs). However, there is concern ICD therapy can prolong survival at the expense of a diminished quality of life.

Study design: Randomized placebo-controlled trial.

Setting: Multiple centers in the U.S., Canada, and New Zealand.

Synopsis: Using 2,479 patients from the Sudden Cardiac Death in Heart Failure trial who were 18 and older and had stable heart failure and depressed left-ventricular function, this study demonstrated no significant quality-of-life difference at 30 months when compared with patients who received ICD, amiodarone, and state-of-the-art medical therapy or an amiodarone placebo and state-of-the-art medical therapy. While functional status did not differ at any time between the three groups, psychological well-being was improved in the ICD group at three months (p=0.01) and 12 months (p=0.03) when compared with the placebo group, but at 30 months there was no difference between the groups.

While the trial was randomized and placebo-controlled, the investigators were unable to blind patients or outcome assessors. Nevertheless, the lack of deterioration of quality of life in ICD patients is reassuring.

 

 

Bottom line: Placement of ICDs in heart failure patients with a high risk of sudden cardiac death does not appear to decrease quality of life.

Citation: Mark DB, Anstrom KJ, Sun JL, et al. Quality of life with defibrillator therapy or amiodarone in heart failure. N Engl J Med. 2008;359:999-1008.

CLINICAL SHORTS

SERIAL 2-POINT ULTRASONOGRAPHY PLUS D-DIMER IS EQUIVALENT TO WHOLE-LEG ULTRASONOGRAPHY FOR DIAGNOSING DVT

Randomized trials show that when comparing serial 2-point ultrasonography plus D-dimer testing with whole-leg ultrasonography, the strategies were equivalent in excluding a first episode of suspected DVT in outpatients.

Citation: Bernardi E, Camporese G, Buller HR, et al. Serial 2-point ultrasonography plus D-dimer vs whole-leg color-coded Doppler ultrasonography for diagnosing suspected symptomatic deep vein thrombosis. JAMA. 2008;300(14):1653-1659.

DAILY HEMODIALYSIS IS COST-EFFECTIVE IN ICU PATIENTS WITH ACUTE KIDNEY INJURY (AKI)

Markov model based on prospective trial data shows daily hemodialysis is cost-effective for AKI in the ICU compared with alternate-day hemodialysis.

Citation: Desai AA, Baras J, Berk BB, et al. Management of acute kidney injury in the intensive care unit. Arch Intern Med. 2008;168(16):1761-1767.

THROMBOLYSIS FOR IN-HOSPITAL STROKE IS SAFE, BUT ASSOCIATED WITH DELAYS

Prospective observational trial shows thrombolysis is safe and effective for in-hospital stroke, but statistically significant delays exist compared with out-of-hospital strokes.

Citation: Masjuan J, Simal P, Fuentes B, et al. In-hospital stroke treated with intravenous tissue plasminogen activator. Stroke. 2008;39:2614-2616.

ALGORITHM CAN IDENTIFY HIGH-RISK HEART FAILURE PATIENTS

Prospective observational study identifies clinical variables for a bedside algorithm, which stratifies the risk of hospitalized heart failure patients for early mortality or readmission to identify those who might benefit from closer follow-up.

Citation: O’Connor CM, Abraham WT, Albert NM, et al. Predictors of mortality after discharge in patients hospitalized with heart failure: an analysis from the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF). Am Heart J. 2008;156(4):662-673.

IN-HOSPITAL SMOKING-CESSATION INTERVENTIONS WITH FOLLOW-UP CAN WORK

Meta-analysis of 33 trials shows in-hospital smoking-cessation counseling followed up with more than one month of outpatient support can be effective.

Citation: Rigotti NA, Munafo MR, Stead LF. Smoking cessation interventions for hospitalized smokers. Arch Intern Med. 2008;168(18):1950-1960.

OMISSION OF KEY INFORMATION DURING SIGN-OUT LEADS TO ADVERSE CONSEQUENCES

An audio-taped study of sign-out among internal medicine house staff teams revealed omission of key information during sign-out resulted in delays in diagnosis or treatment.

Citation: Horwitz LI, Moin T, Krumholz HM, Wang L, Bradley EH. Consequences of inadequate sign-out for patient care. Arch Intern Med. 2008;168(16):1755-1760.

HOSPITAL PALLIATIVE CARE CONSULTATION TEAMS ARE ASSOCIATED WITH HOSPITAL COST SAVINGS

Analysis of administrative data from eight diverse hospitals with palliative-care programs revealed consultation with palliative care saved $1,696 (p<0.001) per hospital admission in patients discharged alive, and $4,098 (p=0.003) per hospital admission in patients who died in the hospital.

Citation: Morrison RS, Penrod JD, Cassel JB, et al. Cost savings associated with U.S. hospital palliative care consultation programs. Arch Intern Med. 2008;168(16):1783-1790.

HIGHER EDUCATIONAL DEBT INFLUENCES INTERNAL MEDICINE RESIDENT CAREER PLANS

U.S. medical graduates with a debt of $50,000 to $99,999 are more likely than those with no debt to choose a hospitalist career, and this preference increased with increased debt level.

Citation: McDonald FS, West CP, Popkave C, Kolars JC. Educational debt and reported career plans among internal medicine residents. Ann Intern Med. 2008;149:416-420.

BRAIN IMAGING IMPORTANT IN IDENTIFYING VASCULAR TERRITORY AFTER TIA OR MINOR STROKE

Neurologists were only moderately reliable at identifying the vascular territory of a TIA or motor stroke, highlighting the fact brain imaging is needed to accurately identify the vascular territories of these events.

Citation: Flossmann E, Redgrave JN, Briley D, Rothwell PM. Reliability of clinical diagnosis of the symptomatic vascular territory in patients with recent transient ischemic attack or minor stroke. Stroke. 2008;39:2457-2460.

HIGH-DOSE VITAMIN B SUPPLEMENTATION DOES NOT SLOW COGNITIVE DECLINE IN ALZHEIMER’S DISEASE

Multicenter, randomized, placebo-controlled trial finds no difference in the rate of cognitive decline in patients with Alzheimer’s disease treated with high-dose vitamin B supplements for 18 months.

Citation: Aisen PS, Schneider LS, Sano M, et al. High-dose B vitamin supplementation and cognitive decline in Alzheimer’s disease. JAMA. 2008; 300(15):1774-1783.

 

 

Can a simplified, revised Geneva score retain diagnostic accuracy and clinical utility?

Background: The revised Geneva score is a validated and objective clinical decision rule, but has multiple variables with different weights. This can make the tool cumbersome and difficult to remember, and could lead to inaccurate calculations and misjudgments in patient care.

Study design: Retrospective cohort study.

Setting: Four university-affiliated European hospitals.

Synopsis: Using data from two prior prospective trials involving patients with suspected pulmonary embolism (PE), this study showed re-analysis of these patients with a simplified, revised Geneva score, which gives only one point to each clinical factor, resulted in the same level of diagnostic accuracy. Specifically, data from 1,049 patients was used to construct a receiver-operating characteristic curve analysis comparing the standardized and simplified Geneva score, which showed areas under the curve of 0.75 (95% confidence interval 0.71-0.78) and 0.74 (0.70-0.77), respectively. Additionally, the safety of using this clinical tool to rule out PE was demonstrated when using both a three-level (low-intermediate probability) and a dichotomized scheme (PE unlikely) in combination with a negative D-dimer test.

The retrospective nature of the study was its major limitation. The authors suggest a prospective study to complete validation of the simplified, revised Geneva score.

Bottom line: With prospective analysis, it might be possible to further validate a simplified, revised Geneva score.

Citation: Klok FA, Mos ICM, Nijkeuter M, et al. Simplification of the revised Geneva score for assessing clinical probability of pulmonary embolism. Arch Intern Med. 2008;168(19):2131-2136.

Is the rate of postoperative major adverse cardiac events (MACEs) inversely related to time after percutaneous coronary intervention (PCI) with a drug-eluting stent (DES)?

Background: The American College of Cardiology and the American Heart Association recently released an advisory that included a recommendation to delay elective noncardiac surgery (NCS) for one year after DES placement. However, no large study addresses the timing of NCS after PCI with DES.

Study design: Retrospective observational study.

Setting: Mayo Clinic, Rochester, Minn.

Synopsis: Looking at 520 patients who had NCS after DES at the Mayo Clinic, 5.4% experienced MACEs, but the rate of MACEs was not significantly associated with the time after stent placement to surgery (p=0.337). However, observed rates of MACEs were lower after one year. Elderly patients and those going for emergent surgery are at the highest risk for MACE. Bleeding complications were not associated with antiplatelet use.

Although this study does not provide a clear cutoff time for when it is safe to proceed to NCS after DES, it is somewhat reassuring to see the relatively small number of MACEs and the lack of bleeding complications associated with antiplatelet use. However, careful coordination between hospitalists, cardiologists, anesthesiologists, and surgeons is still needed when coordinating NCS after DES, especially in the elderly or during emergent situations.

Bottom line: While time to noncardiac surgery after drug-eluting stent placement is not associated with major adverse cardiac events, observed rates of events are lower after one year.

Citation: Rabbitts JA, Nuttall GA, Brown MJ, et al. Cardiac risk of non-cardiac surgery after percutaneous coronary intervention with drug-eluting stents. Anesthesiology.2008;109: 596-604.

Is the risk of MACEs and bleeding events for patients undergoing NCS related to the time interval between PCI with bare-metal stent?

Background: In order to prevent thrombosis of bare-metal stents (BMS) placed during percutaneous coronary intervention (PCI), antiplatelet therapy is used. This poses a risk of bleeding, if surgery is needed during the antiplatelet therapy. The American College of Cardiology and the American Heart Association recommends delaying NCS for at least six weeks after PCI with BMS.

 

 

Study design: Retrospective observational study.

Setting: Mayo Clinic, Rochester, Minn.

Synopsis: Looking at 899 patients who had NCS within one year of PCI with BMS at the Mayo Clinic between Jan. 1, 1990, and Jan. 1, 2005, this study found that when NCS was done 30 days or less after PCI with BMS, the MACEs rate was 10.5%, compared with 2.8% when NCS was done 91 or more days after PCI with BMS. After a multivariable analysis, it also was shown bleeding events were not associated with time between PCI with BMS and NCS.

While the American College of Cardiology and the American Heart Association recommends delaying NCS for at least six weeks after PCI with BMS, waiting at least 90 days would permit completion of antiplatelet therapy and re-endothelialization of the stent.

Bottom line: The risk of MACEs with noncardiac surgery is lowest when performed at least 90 days after PCI with bare-metal stent.

Citation: Nuttall GA, Brown MJ, Stombaugh JW, et al. Time and cardiac risk of surgery after bare-metal stent, percutaneous coronary intervention. Anesthesiology. 2008;109: 588-595.

Should we screen extensively for cancer in patients with newly diagnosed venous thromboembolism (VTE)?

Background: It is well known VTE can be the first manifestation of previously undiagnosed cancer. Retrospective studies have suggested “limited” cancer screening, including a history and physical examination, along with basic blood work, adequately identifies malignancy in patients with unexplained VTE. However, more recent prospective studies have suggested more extensive screening, which includes imaging studies or tumor-marker measurement, can increase the rate of cancer detection.

Study design: Systematic review.

Setting: Literature search using MEDLINE, EMBASE, the Cochrane Register of Controlled Trials, and evidence-based medicine reviews.

Synopsis: Thirty-six studies of 9,516 patients with VTE reported the period prevalence of previously undiagnosed cancer from baseline to 12 months was 6.3% (95% confidence interval (CI) of 5.6% to 6.9%) in all patients with VTE, and was even higher in patients with unprovoked VTE, 10% (95% CI 8.6% to 11.3%). Of the 34 articles used for prevalence assessment, an extensive screening strategy using CT scans of the abdomen and pelvis increased the proportion of previously undiagnosed cancer detection from 49.4% (CI, 40.2% to 58.5%; limited screening) to 69.7% (CI, 61.1% to 77.8%) in patients with unprovoked VTE. Ultrasonography of the abdomen and pelvis and tumor-marker screening did not result in a clinically significant increase in the frequency of cancer detection.

Four studies compared the rate of detection of early-stage, previously undiagnosed cancer between the limited and extensive screening strategies. Extensive screening led to an absolute decrease in cancer-related mortality of 1.9%, but this difference was not statistically significant.

In this systematic review, there is a great deal of heterogeneity in the studies. Most of the studies did not look at whether an increase in detection of new malignant conditions resulted in a change in the detection rate of early-stage cancer, or a decrease in cancer-related morbidity, cancer-related mortality, or overall mortality. Furthermore, the studies did not assess the consequences of extensive screening, such as patient anxiety and discomfort, testing complications, burden of additional tests for false-positive results, or cost-effectiveness. However, it is important for hospitalists to recognize undiagnosed cancer is common in unexplained VTE and warrants at least a limited-screening approach with more extensive screening.

Bottom line: Although the prevalence of undiagnosed cancer is common in VTE, extensive screening did not offer a cancer-related mortality benefit. CT of the abdomen and pelvis did, however, lead to a greater number of cancer diagnoses in patients with unexplained VTE.

 

 

Citation: Carrier M, Le Gal G, Wells PS, Fergusson D, Ramsay T, Rodger MA. Systematic review: the Trousseau syndrome revisited: should we screen extensively for cancer in patients with venous thromboembolism? Ann Intern Med. 2008;149: 323-333.

Does the use of preadmission statins decrease the risk of death, bacteremia, and pulmonary complications in patients admitted with pneumonia?

Background: Both experimental and clinical studies have suggested statins improve outcomes in severe infections, such as sepsis. This is thought to be due to the antithrombotic, anti-inflammatory, and immunomodulatory effects of statins. However, previous studies on the effect of statins on pneumonia have conflicting outcomes.

Study design: Population-based cohort study of 29,900 patients.

Setting: Danish Health Registry.

Synopsis: Researchers studied patients ages 15 years and older hospitalized with pneumonia for the first time between January 1997 and December 2004. While statin users had more co-morbidities than nonusers, the 30-day mortality was 10.3% in users, compared with 15.7% in nonusers, corresponding to an adjusted 30-day mortality rate ratio of 0.69 (95% CI of 0.58-0.82). The 90-day mortality ratio was 16.8% in users, compared with 22.4% in nonusers, corresponding to an adjusted 90-day mortality ratio of 0.75 (95% CI of 0.65-0.86). Former use of statins was not associated with a decreased risk of death. The adjusted risk for bacteremia and pulmonary complications was not significantly different between nonusers and users.

Because this was an observational study, a causal relationship cannot be determined. Hospitalists should be alerted to the possibility statins might, in the future, prove to be a standard treatment modality in pneumonia. A randomized, double-blind trial might help further determine the effect of the acute use of statins on pneumonia outcomes.

Bottom line: Preadmission statin use is associated with a decrease in 30- and 90-day mortality in pneumonia.

Citation: Thomsen RW, Riis A, Kornum JB, Christensen S, Johnsen SP, Sorensen HT. Preadmission use of statins and outcomes after hospitalization with pneumonia. Arch Intern Med. 2008;168(19):2081-2087.

Do outcomes differ when patients with acute myocardial infarction (MI) undergo PCI with drug-eluting stents (DES) compared with bare-metal stents?

Background: Randomized trials comparing drug-eluting stents with bare-metal stents in acute MI have been limited in size and duration. Concern exists regarding higher mortality among patients with ST-elevation MI treated with DES.

Study design: Observational, cohort study.

Setting: Patients were identified from a state-mandated database, in which all PCI performed in Massachusetts are reported.

Synopsis: Between April 2003 and September 2004, 7,217 eligible patients underwent stenting for acute MI. They were assigned to either the DES group or the bare-metal stent (BMS) group using propensity score matching. Patients in the DES group had lower mortality at two years, compared to a matched cohort of patients in the BMS group with MI (10.7% vs. 12.8%; absolute risk difference, -2.1%, CI, -3.8% to -0.4%). A statistically significant difference was noted among patients with or without ST-elevation MI.

The rates of target vessel revascularization at two years with MI were significantly lower among patients receiving DES than among those receiving BMS (9.6% vs. 14.5%; risk difference, -4.9%; CI, -6.1% to -3.1%).

The study is limited by its observational nature and residual confounding bias after matching. Importantly, this study was performed to determine if DESs were harmful, and the finding of reduced mortality was unanticipated.

Bottom line: Although patients with acute MI treated with drug-eluting stents had lower mortality and repeat revascularization rates compared with bare-metal stents, this outcome merits confirmation in randomized trials.

Citation: Mauri L, Silbaugh TS, Garg P, et al. Drug-eluting or bare-metal stents for acute myocardial infarction. N Engl J Med. 2008;359 (13):1330-1342.

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SHM Welcomes New Board Member

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It has been a good year for Eric Howell, MD, FHM. Not only is he the 2009 recipient of SHM’s Award for Excellence in Teaching, but he also is the society’s newest board member.

Dr. Howell, who studied engineering before becoming a hospitalist, is director of the hospitalist division at Johns Hopkins Bayview Medical Center in Baltimore. An SHM member since 2000, he mentors 120 medical students as an assistant professor at the Johns Hopkins School of Medicine.

Dr. Howell, who is chair of SHM’s Leadership Committee and a member of the Public Policy Committee, was added to the 12-seat board this spring. Dr. Howell recently spoke to TH eWire about his award and his new position.

Question: What do you hope to accomplish during your SHM board tenure?

Answer:I am passionate about hospital medicine and enjoy advocating for hospitalists. I thought being a board member would be a mix of these two passions. My goal is to help hospitalists improve the care of their patients.

Q: How did you develop this passion for HM?

A: I love fixing broken things—improving on the hospital processes. I am an electrical engineer, and there is no specialty more based on systems improvement than hospital medicine. When I started, hospitalists were the red-headed stepchildren. Now they are implementers of quality improvement. I love patients, but I really love looking at systems and improving them.

Q: What do you see as the future of HM?

A: I hope it becomes a national leader for patients in hospital and quality improvement. I hope we set the stage nationally for changes in healthcare, such as [President] Obama is proposing. Hospitalists as individuals have been instrumental in advocating for patients. I’d like to see hospital medicine become the doctor-patient advocate.

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It has been a good year for Eric Howell, MD, FHM. Not only is he the 2009 recipient of SHM’s Award for Excellence in Teaching, but he also is the society’s newest board member.

Dr. Howell, who studied engineering before becoming a hospitalist, is director of the hospitalist division at Johns Hopkins Bayview Medical Center in Baltimore. An SHM member since 2000, he mentors 120 medical students as an assistant professor at the Johns Hopkins School of Medicine.

Dr. Howell, who is chair of SHM’s Leadership Committee and a member of the Public Policy Committee, was added to the 12-seat board this spring. Dr. Howell recently spoke to TH eWire about his award and his new position.

Question: What do you hope to accomplish during your SHM board tenure?

Answer:I am passionate about hospital medicine and enjoy advocating for hospitalists. I thought being a board member would be a mix of these two passions. My goal is to help hospitalists improve the care of their patients.

Q: How did you develop this passion for HM?

A: I love fixing broken things—improving on the hospital processes. I am an electrical engineer, and there is no specialty more based on systems improvement than hospital medicine. When I started, hospitalists were the red-headed stepchildren. Now they are implementers of quality improvement. I love patients, but I really love looking at systems and improving them.

Q: What do you see as the future of HM?

A: I hope it becomes a national leader for patients in hospital and quality improvement. I hope we set the stage nationally for changes in healthcare, such as [President] Obama is proposing. Hospitalists as individuals have been instrumental in advocating for patients. I’d like to see hospital medicine become the doctor-patient advocate.

It has been a good year for Eric Howell, MD, FHM. Not only is he the 2009 recipient of SHM’s Award for Excellence in Teaching, but he also is the society’s newest board member.

Dr. Howell, who studied engineering before becoming a hospitalist, is director of the hospitalist division at Johns Hopkins Bayview Medical Center in Baltimore. An SHM member since 2000, he mentors 120 medical students as an assistant professor at the Johns Hopkins School of Medicine.

Dr. Howell, who is chair of SHM’s Leadership Committee and a member of the Public Policy Committee, was added to the 12-seat board this spring. Dr. Howell recently spoke to TH eWire about his award and his new position.

Question: What do you hope to accomplish during your SHM board tenure?

Answer:I am passionate about hospital medicine and enjoy advocating for hospitalists. I thought being a board member would be a mix of these two passions. My goal is to help hospitalists improve the care of their patients.

Q: How did you develop this passion for HM?

A: I love fixing broken things—improving on the hospital processes. I am an electrical engineer, and there is no specialty more based on systems improvement than hospital medicine. When I started, hospitalists were the red-headed stepchildren. Now they are implementers of quality improvement. I love patients, but I really love looking at systems and improving them.

Q: What do you see as the future of HM?

A: I hope it becomes a national leader for patients in hospital and quality improvement. I hope we set the stage nationally for changes in healthcare, such as [President] Obama is proposing. Hospitalists as individuals have been instrumental in advocating for patients. I’d like to see hospital medicine become the doctor-patient advocate.

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More Money, More Problems

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Hospitalists should be mindful that President Obama's half-billion-dollar commitment to new funding for community health centers (CHCs) could translate into unexpected compensation and burnout issues in the coming years, according to an SHM Public Policy Committee member.

Felix Aguirre, MD, FHM, vice president of medical affairs for IPC: The Hospitalist Company, says that until long-term healthcare reform is implemented, Obama’s $493 million in CHC grants "should be a wash."

Dr. Aguirre cautions that American Recovery and Reinvestment Act funding could have unintended consequences. For example, some clinics might raise compensation standards to retain or recruit hospitalists in order to deal with increased patient census. That increase could force local bidding wars for hospitalists at a time when supply is short.

“They will have a bit more money to attract those hospitalists,” Dr. Aguirre says.

In San Antonio, where Dr. Aguirre works, the effect could be even more pronounced, as one in four Texans are uninsured and more likely to take advantage of federally qualified health centers. In fact, 2007 federal data show roughly 40% of CHC patients were uninsured.

U.S. Health and Human Services officials say the stimulus money will provide care to nearly 3 million additional patients in the next two years, including roughly 1 million people without insurance. The added workload could cause burnout in hospitalists serving those institutions but who specialize in HM in part for the quality of life and scheduling perks that it affords.

"The ones that work with the CHCs would have more volume, but less chance of collecting on it, unless they have some arrangement to collect on that," Dr. Aguirre says. "There will be stress with increased volume."

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Hospitalists should be mindful that President Obama's half-billion-dollar commitment to new funding for community health centers (CHCs) could translate into unexpected compensation and burnout issues in the coming years, according to an SHM Public Policy Committee member.

Felix Aguirre, MD, FHM, vice president of medical affairs for IPC: The Hospitalist Company, says that until long-term healthcare reform is implemented, Obama’s $493 million in CHC grants "should be a wash."

Dr. Aguirre cautions that American Recovery and Reinvestment Act funding could have unintended consequences. For example, some clinics might raise compensation standards to retain or recruit hospitalists in order to deal with increased patient census. That increase could force local bidding wars for hospitalists at a time when supply is short.

“They will have a bit more money to attract those hospitalists,” Dr. Aguirre says.

In San Antonio, where Dr. Aguirre works, the effect could be even more pronounced, as one in four Texans are uninsured and more likely to take advantage of federally qualified health centers. In fact, 2007 federal data show roughly 40% of CHC patients were uninsured.

U.S. Health and Human Services officials say the stimulus money will provide care to nearly 3 million additional patients in the next two years, including roughly 1 million people without insurance. The added workload could cause burnout in hospitalists serving those institutions but who specialize in HM in part for the quality of life and scheduling perks that it affords.

"The ones that work with the CHCs would have more volume, but less chance of collecting on it, unless they have some arrangement to collect on that," Dr. Aguirre says. "There will be stress with increased volume."

Hospitalists should be mindful that President Obama's half-billion-dollar commitment to new funding for community health centers (CHCs) could translate into unexpected compensation and burnout issues in the coming years, according to an SHM Public Policy Committee member.

Felix Aguirre, MD, FHM, vice president of medical affairs for IPC: The Hospitalist Company, says that until long-term healthcare reform is implemented, Obama’s $493 million in CHC grants "should be a wash."

Dr. Aguirre cautions that American Recovery and Reinvestment Act funding could have unintended consequences. For example, some clinics might raise compensation standards to retain or recruit hospitalists in order to deal with increased patient census. That increase could force local bidding wars for hospitalists at a time when supply is short.

“They will have a bit more money to attract those hospitalists,” Dr. Aguirre says.

In San Antonio, where Dr. Aguirre works, the effect could be even more pronounced, as one in four Texans are uninsured and more likely to take advantage of federally qualified health centers. In fact, 2007 federal data show roughly 40% of CHC patients were uninsured.

U.S. Health and Human Services officials say the stimulus money will provide care to nearly 3 million additional patients in the next two years, including roughly 1 million people without insurance. The added workload could cause burnout in hospitalists serving those institutions but who specialize in HM in part for the quality of life and scheduling perks that it affords.

"The ones that work with the CHCs would have more volume, but less chance of collecting on it, unless they have some arrangement to collect on that," Dr. Aguirre says. "There will be stress with increased volume."

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Night-Shift Solutions

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Karim Godamunne, MD, watched the moving images on the computer screen as he maneuvered the joystick with his hand. Using the computer screen as a guide, he traversed hallways, entered rooms, and zoomed the camera lens in on patients and equipment—all with a slight flick of the controller.

Sounds like a doc playing video games in the back office, right? But entertainment wasn’t what Dr. Godamunne, a hospitalist medical director with Eagle Hospital Physicians in Atlanta, was after. He was busy overseeing a study on admitting ED patients to St. Joseph’s Hospital in Atlanta, but he and the other participating physicians weren’t physically in the ED: With the help of a robot, a computer, and a secure high-speed Internet connection, the physicians obtained patients’ medical histories, performed physical exams, and admitted them in about the same time it normally takes on-site doctors.

“It’s like a video game, but much more. That’s how I describe it to people,” Dr. Godamunne says of the technology used in the study. “You have to be able to visualize what you’re doing.”

About 10 Eagle hospitalists participated in a pilot program last year that aimed to determine whether ED patients could be admitted by remote hospitalists using the RP-7 robot, which was developed by Santa Barbara, Calif.-based InTouch Health. Eagle was so pleased with the small study’s results that it began offering its remote-robot program to hospitals last October and anticipates deploying the first robot for HM work this spring. Eagle CEO Robert Young, MD, MPH, conceived the study and considers his company’s fledgling telemedicine program a solution to the hospitalist shortage, particularly for covering night shifts.

The Future of Round-the-Clock Rounds

Is telemedicine the right fit for your HM group? Consider the following pros and cons before you make a decision:

BENEFITS

  • Less burnout for hospitalists, leading to higher productivity and longevity;
  • Easier hospitalist recruitment, because applicants know they are less likely to work nights;
  • Ability to cover multiple hospitals at one time, mitigating the hospitalist shortage that many areas face;
  • Enhanced access for hospitalists and their patients to medical specialists;
  • Higher technology comfort level among many patients; and
  • Ability to expand hospital market area by employing telemedicine technology at outlying medical clinics and offices.

BARRIERS

  • Reimbursement obstacles for Medicare and some private health insurers;
  • Medical licensing can be time-consuming for telemedicine doctors who serve patients in multiple states;
  • Difficulty getting buy-in from on-site doctors and primary-care physicians who are worried about liability and telemedicine doctors’ competence;
  • Fear of lawsuits by patients treated via telemedicine;
  • Startup technology and training costs; and
  • Potential patient resistance to telemedicine.

“Eagle’s experience is that many hospitalists will be skeptical at first, but once they see it in action, not only does much of the resistance go away, but some become champions for its use,” Dr. Young says. “It is largely a matter of exposure to and experience in using the technology.”

While increasingly common in hospital ICUs and radiology departments, telemedicine is catching on more slowly in HM. Experts and practicing hospitalists cite reimbursement hiccups, a laborious medical licensing process, technology costs, physician and patient resistance, and risk aversion as the main reasons telemedicine isn’t embraced throughout HM. Some think it will take a concerted government effort to nudge hospitals and HM groups to buy into the technology.

Nevertheless, a growing number of physicians and administrators think telemedicine is inevitable, especially as the demand for HM services outpaces the supply. As in within the Eagle system, some hospitalists are positioning themselves to capitalize on the advancing technology.

 

 

The Future Isn’t Far

photo courtesy of The Night Hospitalist Co.
Robots and mobile carts offer hospitalists remote access to multiple patients at multiple facilities.

“I think it’s going to explode,” says Yomi Olusanya, MD, a hospitalist in rural Rolla, Mo., and founder of The Night Hospitalist Co., LLC, a startup that is busy developing a business model to provide nighttime hospital coverage via telemedicine. “I think with increased costs and the shortage of physicians, hospitalist groups are not going to have any choice but to find alternative ways of doing business. I really believe that.”

Dr. Olusanya envisions establishing a team of about 10 telehospitalists who would handle cross-coverage calls at multiple hospitals in multiple states. The hospitalists would use a mobile cart fashioned with a high-resolution, dual-focus video screen; a video camera; and diagnostic equipment, such as a digital stethoscope, to aid in physical exams. Hospital clients would be given a toll-free number to call to connect with a telehospitalist between

7 p.m. and 7 a.m., and on-site nurses would simply wheel the mobile cart into a patient’s room to begin the care. All overnight changes in medical management would be transmitted to the correct hospital floors for insertion into patients’ medical records. The Night Hospitalist plans to cover malpractice insurance for its physicians and charge a nightly rate, which would vary depending on the length of the contract.

The mobile cart costs between $20,000 and $30,000, and Dr. Olusanya is contemplating absorbing that expense just to get groups interested. At this point, he’s not promising prospective clients cost savings. Instead, he’s offering them a way to lighten the physician workload in order to increase productivity, job satisfaction and career longevity.

“We’re trying to sell the idea to hospitalists,” he says. “This is so new that I’m trying to figure out the best model.” After originally including hospital admissions in his business model, he ultimately decided to focus exclusively on cross-coverage calls and leave the admissions to an on-site physician. “At this point, I don’t see the telemed machine in the ED doing an admission of a new patient, because it becomes less efficient,” he explains.

Conversely, Eagle Hospital Physicians’ remote-robot program is designed to do hospital admissions. The RP-7 robot is mobile enough to aid in cross-coverage, but hospitals must be careful not to overburden the machine with floor calls because it takes the robot longer to travel around the hospital than it does for an on-site physician, says Betty Abbott, Eagle’s chief operating officer.

Doctors have to be good at using the robot to act like a human being rather than simply a stationary screen in a room.


—Betty Abbott, COO, Eagle Hospital Physicians, Atlanta

Through the robot, which stands 5 feet 6 inches tall, a remote hospitalist can interact with a patient, the patient’s family, and the physician or nurse through a live, two-way audio and video system. The remote hospitalist can move the robot’s head to view charts and vital signs on monitors, zoom in to look at a patient’s pupils, and use several diagnostic tools with the help of an on-site health provider to conduct a patient exam, Abbott says. The remote hospitalist also can split the robot’s screen to show a patient X-rays, test results, videos, or other multimedia imaging.

“Certainly, using a robot to interact with patients takes some thought,” Abbott says. “Doctors have to be good at using the robot to act like a human being rather than simply a stationary screen in a room.”

The robot received high marks from patients, hospitalists, ED staff, and healthcare providers who participated in the pilot program at St. Joseph’s Hospital, according to the results of Eagle’s unpublished study. The technology is user-friendly enough that all types of healthcare providers can be trained to use it, says Dr. Godamunne. He designed and helped implement the study, and he found patients quickly adapted to the robot once they focused on the physicians’ faces on the screen.

 

 

Financial, Philosophical Hurdles

Hospitalists like Suman Narumanchi, MD, who leads the HM team at Resurrection Medical Center in Chicago, surmise most patients and their primary-care physicians expect doctors—not a robot or telemed cart—to physically be at the bedside in the hospital. As a result, if something goes wrong, the patient and their primary-care physician might respond with lawsuits. For that reason, “there has to be consistency in telemedicine,” Dr. Narumanchi says. “I just think at this point, it is probably a different level of care based on pure luck, because you don’t know who is going to be working that particular night.”

The concept raises interesting questions, says Eric Samson, DO, HM director for IN Compass Health Inc. in Greensboro, N.C. “Such as that of accountability and ownership of outcomes. On the other hand, it seems enticing to limit the multitude of distractions that occur through nighttime floor calls by implementing a cross-cover specialist fielding floor calls from a more-humane time zone—‘Hey, I’m working night call, but during bankers’ hours.’ ”

photo courtesy of The Night Hospitalist Co.
The Night Hospitalist Co.’s mobile cart costs between $20,000 and $30,000.

Protocols vary from hospital to hospital, and it will be difficult for telehospitalists who cover multiple facilities to learn the differences, says John Nelson, MD, FACP, co-founder and past president of SHM, and principal in Nelson/Flores Associates, a national hospitalist practice management consulting firm in La Quinta, Calif. The job becomes even harder if one or more of the hospitals does not have electronic medical records (EMRs) and instead has to fax patient records to the telehospitalist, he says. Before hospitals invest in this expensive technology, a better solution might be to invent another way to address night coverage, such as allowing nonphysician providers (e.g., nurses) sign off on routine items that now require a doctor’s signature, he says.

Robert Cimasi, president of Health Capital Consultants, a St. Louis-based healthcare financial and economic consulting firm, says telemedicine’s ability to connect patients with distant specialists and allow hospitals to share doctors is tremendous, but agrees the technology is expensive and shouldn’t be entered into without a solid game plan, staff buy-in, and a long-term outlook. Although telemedicine proponents insist EMRs aren’t necessary, Cimasi advises hospitals serious about telemedicine to invest in EMRs, along with electronic order entry for their pharmacies and a secure computer network.

“A lot of hospitals aren’t going to have the capital capacity to do this without government help,” Cimasi explains. “The question is whether the political will is there to have a sustained period of investment.”

Eagle’s remote-robot program is less expensive than hiring a nocturnist or using a locum tenens physician, Dr. Young says. He predicts rural hospitals will benefit the most from his company’s program and other telemedicine services in the market because rural hospitals are most affected by the shortage of inpatient physicians. That might be the case, but if telemedicine is to ever make inroads among hospitalists, it will happen at urban hospitals first because they have the patient populations to support it, Dr. Nelson says.

“At larger hospitals where hospitalists are very busy admitting patients and busy checking patients already admitted, I could see using telemedicine to do the cross-coverage,” he says. “But in a small hospital, that wouldn’t make much sense, because there’s not enough patient volume.” TH

Lisa Ryan is a freelance writer based in New Jersey.

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Karim Godamunne, MD, watched the moving images on the computer screen as he maneuvered the joystick with his hand. Using the computer screen as a guide, he traversed hallways, entered rooms, and zoomed the camera lens in on patients and equipment—all with a slight flick of the controller.

Sounds like a doc playing video games in the back office, right? But entertainment wasn’t what Dr. Godamunne, a hospitalist medical director with Eagle Hospital Physicians in Atlanta, was after. He was busy overseeing a study on admitting ED patients to St. Joseph’s Hospital in Atlanta, but he and the other participating physicians weren’t physically in the ED: With the help of a robot, a computer, and a secure high-speed Internet connection, the physicians obtained patients’ medical histories, performed physical exams, and admitted them in about the same time it normally takes on-site doctors.

“It’s like a video game, but much more. That’s how I describe it to people,” Dr. Godamunne says of the technology used in the study. “You have to be able to visualize what you’re doing.”

About 10 Eagle hospitalists participated in a pilot program last year that aimed to determine whether ED patients could be admitted by remote hospitalists using the RP-7 robot, which was developed by Santa Barbara, Calif.-based InTouch Health. Eagle was so pleased with the small study’s results that it began offering its remote-robot program to hospitals last October and anticipates deploying the first robot for HM work this spring. Eagle CEO Robert Young, MD, MPH, conceived the study and considers his company’s fledgling telemedicine program a solution to the hospitalist shortage, particularly for covering night shifts.

The Future of Round-the-Clock Rounds

Is telemedicine the right fit for your HM group? Consider the following pros and cons before you make a decision:

BENEFITS

  • Less burnout for hospitalists, leading to higher productivity and longevity;
  • Easier hospitalist recruitment, because applicants know they are less likely to work nights;
  • Ability to cover multiple hospitals at one time, mitigating the hospitalist shortage that many areas face;
  • Enhanced access for hospitalists and their patients to medical specialists;
  • Higher technology comfort level among many patients; and
  • Ability to expand hospital market area by employing telemedicine technology at outlying medical clinics and offices.

BARRIERS

  • Reimbursement obstacles for Medicare and some private health insurers;
  • Medical licensing can be time-consuming for telemedicine doctors who serve patients in multiple states;
  • Difficulty getting buy-in from on-site doctors and primary-care physicians who are worried about liability and telemedicine doctors’ competence;
  • Fear of lawsuits by patients treated via telemedicine;
  • Startup technology and training costs; and
  • Potential patient resistance to telemedicine.

“Eagle’s experience is that many hospitalists will be skeptical at first, but once they see it in action, not only does much of the resistance go away, but some become champions for its use,” Dr. Young says. “It is largely a matter of exposure to and experience in using the technology.”

While increasingly common in hospital ICUs and radiology departments, telemedicine is catching on more slowly in HM. Experts and practicing hospitalists cite reimbursement hiccups, a laborious medical licensing process, technology costs, physician and patient resistance, and risk aversion as the main reasons telemedicine isn’t embraced throughout HM. Some think it will take a concerted government effort to nudge hospitals and HM groups to buy into the technology.

Nevertheless, a growing number of physicians and administrators think telemedicine is inevitable, especially as the demand for HM services outpaces the supply. As in within the Eagle system, some hospitalists are positioning themselves to capitalize on the advancing technology.

 

 

The Future Isn’t Far

photo courtesy of The Night Hospitalist Co.
Robots and mobile carts offer hospitalists remote access to multiple patients at multiple facilities.

“I think it’s going to explode,” says Yomi Olusanya, MD, a hospitalist in rural Rolla, Mo., and founder of The Night Hospitalist Co., LLC, a startup that is busy developing a business model to provide nighttime hospital coverage via telemedicine. “I think with increased costs and the shortage of physicians, hospitalist groups are not going to have any choice but to find alternative ways of doing business. I really believe that.”

Dr. Olusanya envisions establishing a team of about 10 telehospitalists who would handle cross-coverage calls at multiple hospitals in multiple states. The hospitalists would use a mobile cart fashioned with a high-resolution, dual-focus video screen; a video camera; and diagnostic equipment, such as a digital stethoscope, to aid in physical exams. Hospital clients would be given a toll-free number to call to connect with a telehospitalist between

7 p.m. and 7 a.m., and on-site nurses would simply wheel the mobile cart into a patient’s room to begin the care. All overnight changes in medical management would be transmitted to the correct hospital floors for insertion into patients’ medical records. The Night Hospitalist plans to cover malpractice insurance for its physicians and charge a nightly rate, which would vary depending on the length of the contract.

The mobile cart costs between $20,000 and $30,000, and Dr. Olusanya is contemplating absorbing that expense just to get groups interested. At this point, he’s not promising prospective clients cost savings. Instead, he’s offering them a way to lighten the physician workload in order to increase productivity, job satisfaction and career longevity.

“We’re trying to sell the idea to hospitalists,” he says. “This is so new that I’m trying to figure out the best model.” After originally including hospital admissions in his business model, he ultimately decided to focus exclusively on cross-coverage calls and leave the admissions to an on-site physician. “At this point, I don’t see the telemed machine in the ED doing an admission of a new patient, because it becomes less efficient,” he explains.

Conversely, Eagle Hospital Physicians’ remote-robot program is designed to do hospital admissions. The RP-7 robot is mobile enough to aid in cross-coverage, but hospitals must be careful not to overburden the machine with floor calls because it takes the robot longer to travel around the hospital than it does for an on-site physician, says Betty Abbott, Eagle’s chief operating officer.

Doctors have to be good at using the robot to act like a human being rather than simply a stationary screen in a room.


—Betty Abbott, COO, Eagle Hospital Physicians, Atlanta

Through the robot, which stands 5 feet 6 inches tall, a remote hospitalist can interact with a patient, the patient’s family, and the physician or nurse through a live, two-way audio and video system. The remote hospitalist can move the robot’s head to view charts and vital signs on monitors, zoom in to look at a patient’s pupils, and use several diagnostic tools with the help of an on-site health provider to conduct a patient exam, Abbott says. The remote hospitalist also can split the robot’s screen to show a patient X-rays, test results, videos, or other multimedia imaging.

“Certainly, using a robot to interact with patients takes some thought,” Abbott says. “Doctors have to be good at using the robot to act like a human being rather than simply a stationary screen in a room.”

The robot received high marks from patients, hospitalists, ED staff, and healthcare providers who participated in the pilot program at St. Joseph’s Hospital, according to the results of Eagle’s unpublished study. The technology is user-friendly enough that all types of healthcare providers can be trained to use it, says Dr. Godamunne. He designed and helped implement the study, and he found patients quickly adapted to the robot once they focused on the physicians’ faces on the screen.

 

 

Financial, Philosophical Hurdles

Hospitalists like Suman Narumanchi, MD, who leads the HM team at Resurrection Medical Center in Chicago, surmise most patients and their primary-care physicians expect doctors—not a robot or telemed cart—to physically be at the bedside in the hospital. As a result, if something goes wrong, the patient and their primary-care physician might respond with lawsuits. For that reason, “there has to be consistency in telemedicine,” Dr. Narumanchi says. “I just think at this point, it is probably a different level of care based on pure luck, because you don’t know who is going to be working that particular night.”

The concept raises interesting questions, says Eric Samson, DO, HM director for IN Compass Health Inc. in Greensboro, N.C. “Such as that of accountability and ownership of outcomes. On the other hand, it seems enticing to limit the multitude of distractions that occur through nighttime floor calls by implementing a cross-cover specialist fielding floor calls from a more-humane time zone—‘Hey, I’m working night call, but during bankers’ hours.’ ”

photo courtesy of The Night Hospitalist Co.
The Night Hospitalist Co.’s mobile cart costs between $20,000 and $30,000.

Protocols vary from hospital to hospital, and it will be difficult for telehospitalists who cover multiple facilities to learn the differences, says John Nelson, MD, FACP, co-founder and past president of SHM, and principal in Nelson/Flores Associates, a national hospitalist practice management consulting firm in La Quinta, Calif. The job becomes even harder if one or more of the hospitals does not have electronic medical records (EMRs) and instead has to fax patient records to the telehospitalist, he says. Before hospitals invest in this expensive technology, a better solution might be to invent another way to address night coverage, such as allowing nonphysician providers (e.g., nurses) sign off on routine items that now require a doctor’s signature, he says.

Robert Cimasi, president of Health Capital Consultants, a St. Louis-based healthcare financial and economic consulting firm, says telemedicine’s ability to connect patients with distant specialists and allow hospitals to share doctors is tremendous, but agrees the technology is expensive and shouldn’t be entered into without a solid game plan, staff buy-in, and a long-term outlook. Although telemedicine proponents insist EMRs aren’t necessary, Cimasi advises hospitals serious about telemedicine to invest in EMRs, along with electronic order entry for their pharmacies and a secure computer network.

“A lot of hospitals aren’t going to have the capital capacity to do this without government help,” Cimasi explains. “The question is whether the political will is there to have a sustained period of investment.”

Eagle’s remote-robot program is less expensive than hiring a nocturnist or using a locum tenens physician, Dr. Young says. He predicts rural hospitals will benefit the most from his company’s program and other telemedicine services in the market because rural hospitals are most affected by the shortage of inpatient physicians. That might be the case, but if telemedicine is to ever make inroads among hospitalists, it will happen at urban hospitals first because they have the patient populations to support it, Dr. Nelson says.

“At larger hospitals where hospitalists are very busy admitting patients and busy checking patients already admitted, I could see using telemedicine to do the cross-coverage,” he says. “But in a small hospital, that wouldn’t make much sense, because there’s not enough patient volume.” TH

Lisa Ryan is a freelance writer based in New Jersey.

Karim Godamunne, MD, watched the moving images on the computer screen as he maneuvered the joystick with his hand. Using the computer screen as a guide, he traversed hallways, entered rooms, and zoomed the camera lens in on patients and equipment—all with a slight flick of the controller.

Sounds like a doc playing video games in the back office, right? But entertainment wasn’t what Dr. Godamunne, a hospitalist medical director with Eagle Hospital Physicians in Atlanta, was after. He was busy overseeing a study on admitting ED patients to St. Joseph’s Hospital in Atlanta, but he and the other participating physicians weren’t physically in the ED: With the help of a robot, a computer, and a secure high-speed Internet connection, the physicians obtained patients’ medical histories, performed physical exams, and admitted them in about the same time it normally takes on-site doctors.

“It’s like a video game, but much more. That’s how I describe it to people,” Dr. Godamunne says of the technology used in the study. “You have to be able to visualize what you’re doing.”

About 10 Eagle hospitalists participated in a pilot program last year that aimed to determine whether ED patients could be admitted by remote hospitalists using the RP-7 robot, which was developed by Santa Barbara, Calif.-based InTouch Health. Eagle was so pleased with the small study’s results that it began offering its remote-robot program to hospitals last October and anticipates deploying the first robot for HM work this spring. Eagle CEO Robert Young, MD, MPH, conceived the study and considers his company’s fledgling telemedicine program a solution to the hospitalist shortage, particularly for covering night shifts.

The Future of Round-the-Clock Rounds

Is telemedicine the right fit for your HM group? Consider the following pros and cons before you make a decision:

BENEFITS

  • Less burnout for hospitalists, leading to higher productivity and longevity;
  • Easier hospitalist recruitment, because applicants know they are less likely to work nights;
  • Ability to cover multiple hospitals at one time, mitigating the hospitalist shortage that many areas face;
  • Enhanced access for hospitalists and their patients to medical specialists;
  • Higher technology comfort level among many patients; and
  • Ability to expand hospital market area by employing telemedicine technology at outlying medical clinics and offices.

BARRIERS

  • Reimbursement obstacles for Medicare and some private health insurers;
  • Medical licensing can be time-consuming for telemedicine doctors who serve patients in multiple states;
  • Difficulty getting buy-in from on-site doctors and primary-care physicians who are worried about liability and telemedicine doctors’ competence;
  • Fear of lawsuits by patients treated via telemedicine;
  • Startup technology and training costs; and
  • Potential patient resistance to telemedicine.

“Eagle’s experience is that many hospitalists will be skeptical at first, but once they see it in action, not only does much of the resistance go away, but some become champions for its use,” Dr. Young says. “It is largely a matter of exposure to and experience in using the technology.”

While increasingly common in hospital ICUs and radiology departments, telemedicine is catching on more slowly in HM. Experts and practicing hospitalists cite reimbursement hiccups, a laborious medical licensing process, technology costs, physician and patient resistance, and risk aversion as the main reasons telemedicine isn’t embraced throughout HM. Some think it will take a concerted government effort to nudge hospitals and HM groups to buy into the technology.

Nevertheless, a growing number of physicians and administrators think telemedicine is inevitable, especially as the demand for HM services outpaces the supply. As in within the Eagle system, some hospitalists are positioning themselves to capitalize on the advancing technology.

 

 

The Future Isn’t Far

photo courtesy of The Night Hospitalist Co.
Robots and mobile carts offer hospitalists remote access to multiple patients at multiple facilities.

“I think it’s going to explode,” says Yomi Olusanya, MD, a hospitalist in rural Rolla, Mo., and founder of The Night Hospitalist Co., LLC, a startup that is busy developing a business model to provide nighttime hospital coverage via telemedicine. “I think with increased costs and the shortage of physicians, hospitalist groups are not going to have any choice but to find alternative ways of doing business. I really believe that.”

Dr. Olusanya envisions establishing a team of about 10 telehospitalists who would handle cross-coverage calls at multiple hospitals in multiple states. The hospitalists would use a mobile cart fashioned with a high-resolution, dual-focus video screen; a video camera; and diagnostic equipment, such as a digital stethoscope, to aid in physical exams. Hospital clients would be given a toll-free number to call to connect with a telehospitalist between

7 p.m. and 7 a.m., and on-site nurses would simply wheel the mobile cart into a patient’s room to begin the care. All overnight changes in medical management would be transmitted to the correct hospital floors for insertion into patients’ medical records. The Night Hospitalist plans to cover malpractice insurance for its physicians and charge a nightly rate, which would vary depending on the length of the contract.

The mobile cart costs between $20,000 and $30,000, and Dr. Olusanya is contemplating absorbing that expense just to get groups interested. At this point, he’s not promising prospective clients cost savings. Instead, he’s offering them a way to lighten the physician workload in order to increase productivity, job satisfaction and career longevity.

“We’re trying to sell the idea to hospitalists,” he says. “This is so new that I’m trying to figure out the best model.” After originally including hospital admissions in his business model, he ultimately decided to focus exclusively on cross-coverage calls and leave the admissions to an on-site physician. “At this point, I don’t see the telemed machine in the ED doing an admission of a new patient, because it becomes less efficient,” he explains.

Conversely, Eagle Hospital Physicians’ remote-robot program is designed to do hospital admissions. The RP-7 robot is mobile enough to aid in cross-coverage, but hospitals must be careful not to overburden the machine with floor calls because it takes the robot longer to travel around the hospital than it does for an on-site physician, says Betty Abbott, Eagle’s chief operating officer.

Doctors have to be good at using the robot to act like a human being rather than simply a stationary screen in a room.


—Betty Abbott, COO, Eagle Hospital Physicians, Atlanta

Through the robot, which stands 5 feet 6 inches tall, a remote hospitalist can interact with a patient, the patient’s family, and the physician or nurse through a live, two-way audio and video system. The remote hospitalist can move the robot’s head to view charts and vital signs on monitors, zoom in to look at a patient’s pupils, and use several diagnostic tools with the help of an on-site health provider to conduct a patient exam, Abbott says. The remote hospitalist also can split the robot’s screen to show a patient X-rays, test results, videos, or other multimedia imaging.

“Certainly, using a robot to interact with patients takes some thought,” Abbott says. “Doctors have to be good at using the robot to act like a human being rather than simply a stationary screen in a room.”

The robot received high marks from patients, hospitalists, ED staff, and healthcare providers who participated in the pilot program at St. Joseph’s Hospital, according to the results of Eagle’s unpublished study. The technology is user-friendly enough that all types of healthcare providers can be trained to use it, says Dr. Godamunne. He designed and helped implement the study, and he found patients quickly adapted to the robot once they focused on the physicians’ faces on the screen.

 

 

Financial, Philosophical Hurdles

Hospitalists like Suman Narumanchi, MD, who leads the HM team at Resurrection Medical Center in Chicago, surmise most patients and their primary-care physicians expect doctors—not a robot or telemed cart—to physically be at the bedside in the hospital. As a result, if something goes wrong, the patient and their primary-care physician might respond with lawsuits. For that reason, “there has to be consistency in telemedicine,” Dr. Narumanchi says. “I just think at this point, it is probably a different level of care based on pure luck, because you don’t know who is going to be working that particular night.”

The concept raises interesting questions, says Eric Samson, DO, HM director for IN Compass Health Inc. in Greensboro, N.C. “Such as that of accountability and ownership of outcomes. On the other hand, it seems enticing to limit the multitude of distractions that occur through nighttime floor calls by implementing a cross-cover specialist fielding floor calls from a more-humane time zone—‘Hey, I’m working night call, but during bankers’ hours.’ ”

photo courtesy of The Night Hospitalist Co.
The Night Hospitalist Co.’s mobile cart costs between $20,000 and $30,000.

Protocols vary from hospital to hospital, and it will be difficult for telehospitalists who cover multiple facilities to learn the differences, says John Nelson, MD, FACP, co-founder and past president of SHM, and principal in Nelson/Flores Associates, a national hospitalist practice management consulting firm in La Quinta, Calif. The job becomes even harder if one or more of the hospitals does not have electronic medical records (EMRs) and instead has to fax patient records to the telehospitalist, he says. Before hospitals invest in this expensive technology, a better solution might be to invent another way to address night coverage, such as allowing nonphysician providers (e.g., nurses) sign off on routine items that now require a doctor’s signature, he says.

Robert Cimasi, president of Health Capital Consultants, a St. Louis-based healthcare financial and economic consulting firm, says telemedicine’s ability to connect patients with distant specialists and allow hospitals to share doctors is tremendous, but agrees the technology is expensive and shouldn’t be entered into without a solid game plan, staff buy-in, and a long-term outlook. Although telemedicine proponents insist EMRs aren’t necessary, Cimasi advises hospitals serious about telemedicine to invest in EMRs, along with electronic order entry for their pharmacies and a secure computer network.

“A lot of hospitals aren’t going to have the capital capacity to do this without government help,” Cimasi explains. “The question is whether the political will is there to have a sustained period of investment.”

Eagle’s remote-robot program is less expensive than hiring a nocturnist or using a locum tenens physician, Dr. Young says. He predicts rural hospitals will benefit the most from his company’s program and other telemedicine services in the market because rural hospitals are most affected by the shortage of inpatient physicians. That might be the case, but if telemedicine is to ever make inroads among hospitalists, it will happen at urban hospitals first because they have the patient populations to support it, Dr. Nelson says.

“At larger hospitals where hospitalists are very busy admitting patients and busy checking patients already admitted, I could see using telemedicine to do the cross-coverage,” he says. “But in a small hospital, that wouldn’t make much sense, because there’s not enough patient volume.” TH

Lisa Ryan is a freelance writer based in New Jersey.

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A 50‐year‐old man with stage 2 sarcoidosis with pleural involvement

A 50‐year‐old man presented to the emergency department with progressive shortness of breath for 6 months. He described a dry cough, left‐sided chest pain, malaise, night sweats, and a 15‐pound weight loss. The patient had never smoked cigarettes, but he had been exposed to asbestos and wood dust when working at a sawmill. His physical examination was remarkable for decreased breath sounds at the left lung base. The admission blood tests were within normal limits. Chest radiography and a computed tomography (CT) scan of the chest were performed (the CT scan is shown in Figures 1 and 2). The CT scan showed a left pleural effusion with subpleural and peribronchovascular nodules. Also demonstrated on the CT scan were bilateral hilar and mediastinal lymphadenopathies with faint central calcification. As the left‐sided pleural effusion was initially suspected to be malignant, a thoracentesis was performed, and it revealed an exudative effusion. The total white cell count in fluid was 2100/L (lymphocytes, 76%), and cultures for aerobic and anaerobic bacteria, acid fasting bacilli, and fungi were negative. Cytology was negative for malignant cells. On the basis of the findings in the lung parenchyma and the presence of mediastinal lymphadenopathies, fiber‐optic bronchoscopy with bronchoalveolar lavage, protected specimen brushing, transbronchial needle aspiration, and transbronchial biopsies were performed. Mediastinal lymph node cytology was negative for malignant cells, whereas transbronchial biopsies showed noncaseating granulomas (Figure 3). At that time, our differential diagnoses of noncaseating granulomas included mycobacterium infection (although this usually presents caseating granulomas), berylliosis, histoplasmosis, and sarcoidosis. The tuberculin skin test (purified protein derivative) and serology for human immunodeficiency virus were negative. Bronchoalveolar lavage and cultures of lung tissue biopsies as well as needle aspiration from mediastinal lymph nodes were negative for mycobacterial, fungal, and bacterial organisms. The beryllium lymphocyte proliferation test was normal. Serologic antibodies for Aspergillus, Blastomyces, Coccidioides, and Histoplasma were negative. The urinary Histoplasma antigen was negative as well. The Department of Infectious Diseases was consulted, and an empirical treatment for histoplasmosis with itraconazole was started on the basis of the residence of the patient and the presence of noncaseating granulomas. After 1 month of antifungal treatment, there was no significant improvement. Video‐assisted thoracoscopic surgery with pleural biopsy was performed because of persistent pleural effusion and concern about an underlying infectious or malignant process. Pleural biopsies showed noncaseating granulomas (Figure 4). Pleural fluid was sent for adenosine deaminase (17 U/L) and flow cytometry (CD4/CD8 2.71). Cultures and cytology remained negative. A diagnosis of stage 2 sarcoidosis with pleural involvement was made, and treatment with prednisone was started.

Figure 1
Computed tomography scan of the chest: lung window. Bronchovascular and subpleural nodules are shown. There is left‐sided pleural effusion.
Figure 2
Computed tomography scan of the chest: mediastinal window. Bilateral hilar and mediastinal lymphadenopathies with faint central calcification are shown.
Figure 3
Transbronchial biopsy of the lung parenchyma: noncaseating granulomas.
Figure 4
Pleural biopsy: noncaseating granuloma.

Discussion

The overall prevalence of pleural involvement in sarcoidosis is about 3%. Patients with pleural sarcoidosis tend to be between 30 and 50 years of age, in contrast to the usual presentation of sarcoidosis between 20 and 30 years of age. The most common forms of pleural involvement are pleural effusions, pneumothorax, pleural thickening, and pleural nodules.1 Most effusions are usually small or modest in size, with few reports describing massive effusions.2 Recurrent pleural and pericardial effusions due to sarcoidosis have been reported as well.3 The fluid is typically a lymphocytic exudate, and almost all cases describe a CD4 predominant lymphocytic effusion with CD4/CD8 ratios ranging from 2.35 to 8.6.1 The presence of bloody pleural effusions in sarcoidosis most likely represents the rupture of small vessels that are compressed or infiltrated by granulomas.4

The majority of patients with reported sarcoid pleural effusions have stage 2 disease. With the progression of parenchymal disease, the prevalence of pleural effusions decreases, whereas pleural thickening and pneumothorax increase.5 It is important to emphasize that 40% of pleural effusions in sarcoidosis may be due to other causes, such as tuberculosis and mesothelioma. Our patient was initially treated with itraconazole as histoplasmosis is most prevalent in the Central and Eastern United States, especially in Ohio River valleys, where this patient lived.

The prevalence of a pneumothorax in sarcoidosis is up to 4%.1 Pleural thickening can be demonstrated in 11% to 71% of patients with pleural sarcoidosis, and 10% to 20% of these cases have thickening without effusion. Detection of subpleural nodules and cysts has been possible since the introduction of high‐resolution CT scans. Their prevalence in sarcoidosis ranges from 22% to 76%, and they are often described as masses that correspond to nodules seen in both parietal and visceral surfaces. Hilar or mediastinal lymphadenopathy is present on CT in 47% to 94% of patients with sarcoidosis. Lymph node enlargement is usually bilateral, most commonly with right‐sided predominance. The most involved stations are the right lower paratracheal, right hilar, subcarinal, aortopulmonary window, and right interlobar stations. Nodal calcification is noted in 53% with eggshell calcification present in 9%. The enlargement of internal mammary and pericardial lymph nodes requires the exclusion of lymphoma.6

The management of pleural sarcoidosis should be individualized because a majority of these effusions resolve spontaneously in 1 to 3 months.5 There have been reports of resolution in 2 weeks with steroid therapy. Incomplete resolution of the pleural effusions with progression to chronic pleural thickening or a trapped lung has been reported. There is agreement that oral corticosteroid treatment should be considered in patients with severe persistent or progressively worsening respiratory symptoms or declining lung function. Severe symptoms can be considered as those that interfere with essential aspects of the patient's daily life.7 The initial dosage of oral prednisone recommended by the American Thoracic Society, the European Respiratory Society, and the World Association of Sarcoidosis and Other Granulomatous Disorders guidelines is 20 to 40 mg/day.8 Further evaluation is recommended after 1 to 3 months. If the patient responds, the dose should be reduced gradually to a maintenance dose, such as 5 to 15 mg/day of prednisolone. American Thoracic Society/European Respiratory Society/World Association of Sarcoidosis and Other Granulomatous Disorders guidelines advise treatment for at least 1 year. Immunosuppressive, cytotoxic, and immunomodulatory agents have been used to treat patients failing or experiencing adverse effects of steroids. Favorable responses have been reported with methotrexate, leflunomide, azathioprine, cyclophosphamide, chlorambucil, cyclosporine A, antimalarials, tumor necrosis factor inhibitors, and thalidomide. Because of potential serious toxicities associated with cyclophosphamide and chlorambucil, these agents are not recommended.9

Our patient presented with pleural sarcoidosis with a pleural effusion and nodules. Treatment with 20 mg of prednisone daily was started initially. Four weeks after discharge, he was still dyspneic and had persistent left pleural effusion. He also had gained a significant amount of weight and developed bilateral lower extremity edema; these were thought to be secondary to prednisone treatment. Steroids were subsequently tapered, and leflunomide was started. His symptoms improved dramatically after 1 month of treatment with leflunomide and steroids, and 3 months later, his pleural effusion had completely resolved.

References
  1. Soskel NT,Sharma OP.Pleural involvement in sarcoidosis.Curr Opin Pulm Med.2000;6(5):455468.
  2. Claiborne RA,Kerby GR.Pleural sarcoidosis with massive effusion and lung entrapment.Kans Med.1990;91(4):103105.
  3. Navaneethan SD,Venkatesh S,Shrivastava R,Mehta J,Israel R.Recurrent pleural and pericardial effusions due to sarcoidosis.PLoS Med.2005;2(3):e63.
  4. Watarai M,Yazawa M,Yamanda K,Yamamoto H,Yamazaki Y.Pulmonary sarcoidosis with associated bloody pleurisy.Intern Med.2002;41(11):10211023.
  5. Huggins JT,Doelken P,Sahn SA,King L,Judson MA.Pleural effusions in a series of 181 outpatients with sarcoidosis.Chest.2006;129(6):15991604.
  6. Nunes H,Brillet PY,Valeyre D,Brauner MW,Wells AU.Imaging in sarcoidosis.Semin Respir Crit Care Med.2007;28(1):102120.
  7. Coker RK.Guidelines for the use of corticosteroids in the treatment of pulmonary sarcoidosis.Drugs.2007;67(8):11391147.
  8. Hunninghake GW,Costabel U,Ando M, et al.ATS/ERS/WASOG statement on sarcoidosis.Sarcoidosis Vasc Diffuse Lung Dis.1999;16(2):149173.
  9. Lynch JP,Ma YL,Koss MN,White ES.Pulmonary sarcoidosis.Semin Respir Crit Care Med.2007;28(1):5374.
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chest pain, interstitial lung disease, pleural disease (effusion, pneumothorax)
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A 50‐year‐old man presented to the emergency department with progressive shortness of breath for 6 months. He described a dry cough, left‐sided chest pain, malaise, night sweats, and a 15‐pound weight loss. The patient had never smoked cigarettes, but he had been exposed to asbestos and wood dust when working at a sawmill. His physical examination was remarkable for decreased breath sounds at the left lung base. The admission blood tests were within normal limits. Chest radiography and a computed tomography (CT) scan of the chest were performed (the CT scan is shown in Figures 1 and 2). The CT scan showed a left pleural effusion with subpleural and peribronchovascular nodules. Also demonstrated on the CT scan were bilateral hilar and mediastinal lymphadenopathies with faint central calcification. As the left‐sided pleural effusion was initially suspected to be malignant, a thoracentesis was performed, and it revealed an exudative effusion. The total white cell count in fluid was 2100/L (lymphocytes, 76%), and cultures for aerobic and anaerobic bacteria, acid fasting bacilli, and fungi were negative. Cytology was negative for malignant cells. On the basis of the findings in the lung parenchyma and the presence of mediastinal lymphadenopathies, fiber‐optic bronchoscopy with bronchoalveolar lavage, protected specimen brushing, transbronchial needle aspiration, and transbronchial biopsies were performed. Mediastinal lymph node cytology was negative for malignant cells, whereas transbronchial biopsies showed noncaseating granulomas (Figure 3). At that time, our differential diagnoses of noncaseating granulomas included mycobacterium infection (although this usually presents caseating granulomas), berylliosis, histoplasmosis, and sarcoidosis. The tuberculin skin test (purified protein derivative) and serology for human immunodeficiency virus were negative. Bronchoalveolar lavage and cultures of lung tissue biopsies as well as needle aspiration from mediastinal lymph nodes were negative for mycobacterial, fungal, and bacterial organisms. The beryllium lymphocyte proliferation test was normal. Serologic antibodies for Aspergillus, Blastomyces, Coccidioides, and Histoplasma were negative. The urinary Histoplasma antigen was negative as well. The Department of Infectious Diseases was consulted, and an empirical treatment for histoplasmosis with itraconazole was started on the basis of the residence of the patient and the presence of noncaseating granulomas. After 1 month of antifungal treatment, there was no significant improvement. Video‐assisted thoracoscopic surgery with pleural biopsy was performed because of persistent pleural effusion and concern about an underlying infectious or malignant process. Pleural biopsies showed noncaseating granulomas (Figure 4). Pleural fluid was sent for adenosine deaminase (17 U/L) and flow cytometry (CD4/CD8 2.71). Cultures and cytology remained negative. A diagnosis of stage 2 sarcoidosis with pleural involvement was made, and treatment with prednisone was started.

Figure 1
Computed tomography scan of the chest: lung window. Bronchovascular and subpleural nodules are shown. There is left‐sided pleural effusion.
Figure 2
Computed tomography scan of the chest: mediastinal window. Bilateral hilar and mediastinal lymphadenopathies with faint central calcification are shown.
Figure 3
Transbronchial biopsy of the lung parenchyma: noncaseating granulomas.
Figure 4
Pleural biopsy: noncaseating granuloma.

Discussion

The overall prevalence of pleural involvement in sarcoidosis is about 3%. Patients with pleural sarcoidosis tend to be between 30 and 50 years of age, in contrast to the usual presentation of sarcoidosis between 20 and 30 years of age. The most common forms of pleural involvement are pleural effusions, pneumothorax, pleural thickening, and pleural nodules.1 Most effusions are usually small or modest in size, with few reports describing massive effusions.2 Recurrent pleural and pericardial effusions due to sarcoidosis have been reported as well.3 The fluid is typically a lymphocytic exudate, and almost all cases describe a CD4 predominant lymphocytic effusion with CD4/CD8 ratios ranging from 2.35 to 8.6.1 The presence of bloody pleural effusions in sarcoidosis most likely represents the rupture of small vessels that are compressed or infiltrated by granulomas.4

The majority of patients with reported sarcoid pleural effusions have stage 2 disease. With the progression of parenchymal disease, the prevalence of pleural effusions decreases, whereas pleural thickening and pneumothorax increase.5 It is important to emphasize that 40% of pleural effusions in sarcoidosis may be due to other causes, such as tuberculosis and mesothelioma. Our patient was initially treated with itraconazole as histoplasmosis is most prevalent in the Central and Eastern United States, especially in Ohio River valleys, where this patient lived.

The prevalence of a pneumothorax in sarcoidosis is up to 4%.1 Pleural thickening can be demonstrated in 11% to 71% of patients with pleural sarcoidosis, and 10% to 20% of these cases have thickening without effusion. Detection of subpleural nodules and cysts has been possible since the introduction of high‐resolution CT scans. Their prevalence in sarcoidosis ranges from 22% to 76%, and they are often described as masses that correspond to nodules seen in both parietal and visceral surfaces. Hilar or mediastinal lymphadenopathy is present on CT in 47% to 94% of patients with sarcoidosis. Lymph node enlargement is usually bilateral, most commonly with right‐sided predominance. The most involved stations are the right lower paratracheal, right hilar, subcarinal, aortopulmonary window, and right interlobar stations. Nodal calcification is noted in 53% with eggshell calcification present in 9%. The enlargement of internal mammary and pericardial lymph nodes requires the exclusion of lymphoma.6

The management of pleural sarcoidosis should be individualized because a majority of these effusions resolve spontaneously in 1 to 3 months.5 There have been reports of resolution in 2 weeks with steroid therapy. Incomplete resolution of the pleural effusions with progression to chronic pleural thickening or a trapped lung has been reported. There is agreement that oral corticosteroid treatment should be considered in patients with severe persistent or progressively worsening respiratory symptoms or declining lung function. Severe symptoms can be considered as those that interfere with essential aspects of the patient's daily life.7 The initial dosage of oral prednisone recommended by the American Thoracic Society, the European Respiratory Society, and the World Association of Sarcoidosis and Other Granulomatous Disorders guidelines is 20 to 40 mg/day.8 Further evaluation is recommended after 1 to 3 months. If the patient responds, the dose should be reduced gradually to a maintenance dose, such as 5 to 15 mg/day of prednisolone. American Thoracic Society/European Respiratory Society/World Association of Sarcoidosis and Other Granulomatous Disorders guidelines advise treatment for at least 1 year. Immunosuppressive, cytotoxic, and immunomodulatory agents have been used to treat patients failing or experiencing adverse effects of steroids. Favorable responses have been reported with methotrexate, leflunomide, azathioprine, cyclophosphamide, chlorambucil, cyclosporine A, antimalarials, tumor necrosis factor inhibitors, and thalidomide. Because of potential serious toxicities associated with cyclophosphamide and chlorambucil, these agents are not recommended.9

Our patient presented with pleural sarcoidosis with a pleural effusion and nodules. Treatment with 20 mg of prednisone daily was started initially. Four weeks after discharge, he was still dyspneic and had persistent left pleural effusion. He also had gained a significant amount of weight and developed bilateral lower extremity edema; these were thought to be secondary to prednisone treatment. Steroids were subsequently tapered, and leflunomide was started. His symptoms improved dramatically after 1 month of treatment with leflunomide and steroids, and 3 months later, his pleural effusion had completely resolved.

A 50‐year‐old man presented to the emergency department with progressive shortness of breath for 6 months. He described a dry cough, left‐sided chest pain, malaise, night sweats, and a 15‐pound weight loss. The patient had never smoked cigarettes, but he had been exposed to asbestos and wood dust when working at a sawmill. His physical examination was remarkable for decreased breath sounds at the left lung base. The admission blood tests were within normal limits. Chest radiography and a computed tomography (CT) scan of the chest were performed (the CT scan is shown in Figures 1 and 2). The CT scan showed a left pleural effusion with subpleural and peribronchovascular nodules. Also demonstrated on the CT scan were bilateral hilar and mediastinal lymphadenopathies with faint central calcification. As the left‐sided pleural effusion was initially suspected to be malignant, a thoracentesis was performed, and it revealed an exudative effusion. The total white cell count in fluid was 2100/L (lymphocytes, 76%), and cultures for aerobic and anaerobic bacteria, acid fasting bacilli, and fungi were negative. Cytology was negative for malignant cells. On the basis of the findings in the lung parenchyma and the presence of mediastinal lymphadenopathies, fiber‐optic bronchoscopy with bronchoalveolar lavage, protected specimen brushing, transbronchial needle aspiration, and transbronchial biopsies were performed. Mediastinal lymph node cytology was negative for malignant cells, whereas transbronchial biopsies showed noncaseating granulomas (Figure 3). At that time, our differential diagnoses of noncaseating granulomas included mycobacterium infection (although this usually presents caseating granulomas), berylliosis, histoplasmosis, and sarcoidosis. The tuberculin skin test (purified protein derivative) and serology for human immunodeficiency virus were negative. Bronchoalveolar lavage and cultures of lung tissue biopsies as well as needle aspiration from mediastinal lymph nodes were negative for mycobacterial, fungal, and bacterial organisms. The beryllium lymphocyte proliferation test was normal. Serologic antibodies for Aspergillus, Blastomyces, Coccidioides, and Histoplasma were negative. The urinary Histoplasma antigen was negative as well. The Department of Infectious Diseases was consulted, and an empirical treatment for histoplasmosis with itraconazole was started on the basis of the residence of the patient and the presence of noncaseating granulomas. After 1 month of antifungal treatment, there was no significant improvement. Video‐assisted thoracoscopic surgery with pleural biopsy was performed because of persistent pleural effusion and concern about an underlying infectious or malignant process. Pleural biopsies showed noncaseating granulomas (Figure 4). Pleural fluid was sent for adenosine deaminase (17 U/L) and flow cytometry (CD4/CD8 2.71). Cultures and cytology remained negative. A diagnosis of stage 2 sarcoidosis with pleural involvement was made, and treatment with prednisone was started.

Figure 1
Computed tomography scan of the chest: lung window. Bronchovascular and subpleural nodules are shown. There is left‐sided pleural effusion.
Figure 2
Computed tomography scan of the chest: mediastinal window. Bilateral hilar and mediastinal lymphadenopathies with faint central calcification are shown.
Figure 3
Transbronchial biopsy of the lung parenchyma: noncaseating granulomas.
Figure 4
Pleural biopsy: noncaseating granuloma.

Discussion

The overall prevalence of pleural involvement in sarcoidosis is about 3%. Patients with pleural sarcoidosis tend to be between 30 and 50 years of age, in contrast to the usual presentation of sarcoidosis between 20 and 30 years of age. The most common forms of pleural involvement are pleural effusions, pneumothorax, pleural thickening, and pleural nodules.1 Most effusions are usually small or modest in size, with few reports describing massive effusions.2 Recurrent pleural and pericardial effusions due to sarcoidosis have been reported as well.3 The fluid is typically a lymphocytic exudate, and almost all cases describe a CD4 predominant lymphocytic effusion with CD4/CD8 ratios ranging from 2.35 to 8.6.1 The presence of bloody pleural effusions in sarcoidosis most likely represents the rupture of small vessels that are compressed or infiltrated by granulomas.4

The majority of patients with reported sarcoid pleural effusions have stage 2 disease. With the progression of parenchymal disease, the prevalence of pleural effusions decreases, whereas pleural thickening and pneumothorax increase.5 It is important to emphasize that 40% of pleural effusions in sarcoidosis may be due to other causes, such as tuberculosis and mesothelioma. Our patient was initially treated with itraconazole as histoplasmosis is most prevalent in the Central and Eastern United States, especially in Ohio River valleys, where this patient lived.

The prevalence of a pneumothorax in sarcoidosis is up to 4%.1 Pleural thickening can be demonstrated in 11% to 71% of patients with pleural sarcoidosis, and 10% to 20% of these cases have thickening without effusion. Detection of subpleural nodules and cysts has been possible since the introduction of high‐resolution CT scans. Their prevalence in sarcoidosis ranges from 22% to 76%, and they are often described as masses that correspond to nodules seen in both parietal and visceral surfaces. Hilar or mediastinal lymphadenopathy is present on CT in 47% to 94% of patients with sarcoidosis. Lymph node enlargement is usually bilateral, most commonly with right‐sided predominance. The most involved stations are the right lower paratracheal, right hilar, subcarinal, aortopulmonary window, and right interlobar stations. Nodal calcification is noted in 53% with eggshell calcification present in 9%. The enlargement of internal mammary and pericardial lymph nodes requires the exclusion of lymphoma.6

The management of pleural sarcoidosis should be individualized because a majority of these effusions resolve spontaneously in 1 to 3 months.5 There have been reports of resolution in 2 weeks with steroid therapy. Incomplete resolution of the pleural effusions with progression to chronic pleural thickening or a trapped lung has been reported. There is agreement that oral corticosteroid treatment should be considered in patients with severe persistent or progressively worsening respiratory symptoms or declining lung function. Severe symptoms can be considered as those that interfere with essential aspects of the patient's daily life.7 The initial dosage of oral prednisone recommended by the American Thoracic Society, the European Respiratory Society, and the World Association of Sarcoidosis and Other Granulomatous Disorders guidelines is 20 to 40 mg/day.8 Further evaluation is recommended after 1 to 3 months. If the patient responds, the dose should be reduced gradually to a maintenance dose, such as 5 to 15 mg/day of prednisolone. American Thoracic Society/European Respiratory Society/World Association of Sarcoidosis and Other Granulomatous Disorders guidelines advise treatment for at least 1 year. Immunosuppressive, cytotoxic, and immunomodulatory agents have been used to treat patients failing or experiencing adverse effects of steroids. Favorable responses have been reported with methotrexate, leflunomide, azathioprine, cyclophosphamide, chlorambucil, cyclosporine A, antimalarials, tumor necrosis factor inhibitors, and thalidomide. Because of potential serious toxicities associated with cyclophosphamide and chlorambucil, these agents are not recommended.9

Our patient presented with pleural sarcoidosis with a pleural effusion and nodules. Treatment with 20 mg of prednisone daily was started initially. Four weeks after discharge, he was still dyspneic and had persistent left pleural effusion. He also had gained a significant amount of weight and developed bilateral lower extremity edema; these were thought to be secondary to prednisone treatment. Steroids were subsequently tapered, and leflunomide was started. His symptoms improved dramatically after 1 month of treatment with leflunomide and steroids, and 3 months later, his pleural effusion had completely resolved.

References
  1. Soskel NT,Sharma OP.Pleural involvement in sarcoidosis.Curr Opin Pulm Med.2000;6(5):455468.
  2. Claiborne RA,Kerby GR.Pleural sarcoidosis with massive effusion and lung entrapment.Kans Med.1990;91(4):103105.
  3. Navaneethan SD,Venkatesh S,Shrivastava R,Mehta J,Israel R.Recurrent pleural and pericardial effusions due to sarcoidosis.PLoS Med.2005;2(3):e63.
  4. Watarai M,Yazawa M,Yamanda K,Yamamoto H,Yamazaki Y.Pulmonary sarcoidosis with associated bloody pleurisy.Intern Med.2002;41(11):10211023.
  5. Huggins JT,Doelken P,Sahn SA,King L,Judson MA.Pleural effusions in a series of 181 outpatients with sarcoidosis.Chest.2006;129(6):15991604.
  6. Nunes H,Brillet PY,Valeyre D,Brauner MW,Wells AU.Imaging in sarcoidosis.Semin Respir Crit Care Med.2007;28(1):102120.
  7. Coker RK.Guidelines for the use of corticosteroids in the treatment of pulmonary sarcoidosis.Drugs.2007;67(8):11391147.
  8. Hunninghake GW,Costabel U,Ando M, et al.ATS/ERS/WASOG statement on sarcoidosis.Sarcoidosis Vasc Diffuse Lung Dis.1999;16(2):149173.
  9. Lynch JP,Ma YL,Koss MN,White ES.Pulmonary sarcoidosis.Semin Respir Crit Care Med.2007;28(1):5374.
References
  1. Soskel NT,Sharma OP.Pleural involvement in sarcoidosis.Curr Opin Pulm Med.2000;6(5):455468.
  2. Claiborne RA,Kerby GR.Pleural sarcoidosis with massive effusion and lung entrapment.Kans Med.1990;91(4):103105.
  3. Navaneethan SD,Venkatesh S,Shrivastava R,Mehta J,Israel R.Recurrent pleural and pericardial effusions due to sarcoidosis.PLoS Med.2005;2(3):e63.
  4. Watarai M,Yazawa M,Yamanda K,Yamamoto H,Yamazaki Y.Pulmonary sarcoidosis with associated bloody pleurisy.Intern Med.2002;41(11):10211023.
  5. Huggins JT,Doelken P,Sahn SA,King L,Judson MA.Pleural effusions in a series of 181 outpatients with sarcoidosis.Chest.2006;129(6):15991604.
  6. Nunes H,Brillet PY,Valeyre D,Brauner MW,Wells AU.Imaging in sarcoidosis.Semin Respir Crit Care Med.2007;28(1):102120.
  7. Coker RK.Guidelines for the use of corticosteroids in the treatment of pulmonary sarcoidosis.Drugs.2007;67(8):11391147.
  8. Hunninghake GW,Costabel U,Ando M, et al.ATS/ERS/WASOG statement on sarcoidosis.Sarcoidosis Vasc Diffuse Lung Dis.1999;16(2):149173.
  9. Lynch JP,Ma YL,Koss MN,White ES.Pulmonary sarcoidosis.Semin Respir Crit Care Med.2007;28(1):5374.
Issue
Journal of Hospital Medicine - 4(4)
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A 50‐year‐old man with stage 2 sarcoidosis with pleural involvement
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A 50‐year‐old man with stage 2 sarcoidosis with pleural involvement
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Rube Goldberg Coordinated Care

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Dismantling Rube Goldberg: Cutting through chaos to achieve coordinated care

I was 12 years old before I knew her actual name, Le Thi Canh, because we always called her Ba ngoai. She was my grandmother, and this is the story of how she died.

To see my grandmother for the warrior woman that she was to me, you have to know that her farmer father sent her to the city for schooling because he didn't know what else to do with a daughter who was so smart. In early 20th‐century Vietnam, this was an unusual thing to do with a girl. She met my grandfather there, when he was a campus activist, helping him hand out nationalist leaflets. He introduced her to his Communist friends. After the French jailed my grandfather, my grandmother courted him by sending him long letters and care packages while he was in prison. When he was finally released, they married and started a family while he struggled financially as a newspaper publisher and at other odd jobs. But in 1947 his own Communist comrades killed him as part of a party purge. He had been forewarned, and opted to go quietly rather than try to escape because he was promised that this would guarantee her safety. Before they killed him, somewhere in the mountains, my grandfather gave a soldier friend a poem he wrote for his wife. When she told me this story 8 years ago, more than half a century later, she recited his love missive from memory.

At the time of her husband's death, my grandmother had 6 children, the last born just a few weeks before. After a few years of scraping by (she ran her own one‐room school for a while), she decided to leave Hanoi, and migrated south to Saigon with her brood. She was a famously strict parent, to hear my aunts and uncles tell it. She watched them like a hawk, worked full‐time, put them all through school, and eventually rose to a leadership position in the Ministry of Social Work in South Vietnam. My memories of Saigon life are punctuated by scenes of siblings and cousins running around at her regal house, yellow stucco with porticos and black iron gates, at a corner turn in the road, past a cemetery.

On this side of the world, to see her, you would never have thought that my grandmother had led such an epic life. She never worked again after immigrating with us in 1975. She lived on Social Security checks, gardened, said Buddhist prayers, and was nanny to her grandchildren. She watched soap operas religiously, and could report their full plot lines while sitting and knitting. She bundled her many sadnesses in a contented, 4‐foot 9‐inch frame.

Having no home of her own, she would move from one child's house to another every few months so as not to wear out her welcome. But her children lived in Pennsylvania, New Jersey, Florida, Texas, and Maryland. And in most of these cities, she had a different primary care physician. She has 21 grandchildren; 8 of us are physicians. Yet the aunts and uncles told us very little about her medical care. She preferred older‐generation Vietnamese physicians and I'm not sure that they were all competent, but her children did not want to argue with an octogenarian war survivor, and we deferred to their judgment. So we would find out only incidentally, for example, that a doctor prescribed her tuberculosis drugs for a visit to Vietnam.

For many years, Ba ngoai had no major medical problems. She was hypothyroid and hypertensive but on medication and generally high functioning. She had a lumpectomy for early‐stage breast cancer. Then, a year or so after she told me the story of my grandfather's death, Alzheimer's set in. It became harder for her to report symptoms reliably, and she became mildly depressed. Her grandchildren were now birthing our own babies, and we offered these as a distraction, trying to surround her with celebrations of these new fruits of her life labors.

Ba ngoai's decline worsened 3 years ago. She became more easily fatigued, depressed, and confused. A few months before she died, she started to get dyspneic, and couldn't go for short walks any more. In retrospect, I think that her prescription for thyroid replacement somehow fell through the cracks, probably in the transfer of care from one city to another, although there remains a great deal of confusion in the family about exactly what happened. Her thyroxine levels dwindled. One evening in October of that year, at my uncle's house in Maryland, she became severely short of breath and nearly unconscious. They called her Maryland PCP, who sent her to an emergency room at a local hospital. She was admitted in severe congestive heart failure. When the hospitalist spoke with my mother and uncle, he explained that he could take some fluid off her lungs, but that she might need to be intubated and admitted to intensive care. Looking back, I guessed that she probably needed pressors and invasive monitoring. He asked them, Is this what you want? My uncle said, No, it's not. And the hospitalist and the huddle of relatives decided she should come home.

The question was, into whose care would she be discharged? My elders were wary of contacting her PCP, partly because some blamed him for not catching and addressing her symptoms sooner, partly because to even confront him with this perception would cause him, and hence them, to lose face. This seemed too excruciating a scenario to them.

So at last, my uncle called my brother, the oldest grandchild and a very talented clinician. My brother is a pulmonologist, the kind of physician who once did a history and physical on a patient complaining only of Really feeling bad, Doc, and confidently started a steroid infusion before returning the next day with test results confirming his suspicion of Wegener's granulomatosis. He took my grandmother's physical by phone, and told my uncle to increase her furosemide dose. Then he said, I'm on call, but I'll be down there tomorrow. Call everyone together. Most of my relatives were already in town; they had come at news of her decline. She became alert enough for a couple of days to see and recognize most of the faces around her, like so many markers on a long journey. And then she died, slipped away.

I find it hard to define good coordination of care. My instinct as a researcher is to list measurable elements, but the tools we currently have generate metrics that are either reductionistsuch as how rapidly a physician returns a patient's callor so global that they no longer seem actionablesuch as patient satisfaction. But if such metrics set the goal in the distance, it seems useful to also define its counterpartdiscoordinationas a marker of the reality we would like to leave behind us as far as possible. Discoordination includes elements of discontinuity (lost patient history), fragmentation (actions by multiple players), overuse and/or inappropriate use of services, and ultimately, ineffective care (that is, the patient's needs go unmet).

My experience of discoordination was that of a Rube Goldberg contraption. It's composed of innumerable subtasks, each cleverly designed as the easiest solution to a seemingly short‐term problem, as quick fixes, but that in aggregate generate such chaos that the ultimate purpose is lost. They include acts of denial, lies to avoid embarrassment or conflict, and choices of convenience. My mother and her siblings accommodated my grandmother's choice of physicians by (secretly) not always adhering to care recommendations they didn't agree with, instead of challenging her. They took her to different physicians in different cities rather than risk embarrassing (due to an exaggerated sense of the smallness of the Vietnamese community) any one physician by dropping him. Her grandchildren, despite our medical training, found it culturally easier to defer to our elders than to intervene in substandard care. And none of her physicians aggressively followed up to ensure that a frail Alzheimer's patient was getting the care she needed. This is not to suggest that coordination is a simple task because Rube Goldberg machines make simple tasks complicated. Rather, it is a depiction of how indirectly we tend to address the problem.

I imagine a different course of events for my grandmother in the absence of discoordination. What if her children and physicians had understood and acknowledged to one another that her care was fragmented and therefore suboptimal? What if we grandchildren had confronted both Ba Ngoai and our parents sooner about their choice of physicians and offered to take on more of the burden of helping with her care decisions? Would we, as physicians, have been better able to ensure that her providers made rational clinical decisions? And what if she and her family had consistently recognized a single physician as her medical home? Snowbirding is hardly a rare phenomenon among Medicare patients; we could have designated one physician as primarily responsible for coordinating her care even without limiting her travel.

Care coordination is an inherently human activity. Supportive elements such as efficient transfer of medical information, resources for patient education and self‐care, and adequate reimbursement can take us to the brink of, but not actually bridge, the chasm that we want to cross. Traversing that divide sometimes requires settling turf issues over undesirable responsibilities between different physicians and between physicians and other providers; clarifying who has primary responsibility for different types of decisions (I lead on cardiac issues and her son leads on health maintenance); and the violation of cultural norms of patients, families, and/or providers. These can be uncomfortable, unpleasant conversations that at times seem beside the point. But in aggregate, they are the work of coordination, because they force us to align our expectations of one another. No level of information technology could have dismantled the Rube Goldberg machine that trapped my grandmother. Her last of many lessons for me was that emotional courage, honesty, and perseverance offer a much more direct path through the muck.

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I was 12 years old before I knew her actual name, Le Thi Canh, because we always called her Ba ngoai. She was my grandmother, and this is the story of how she died.

To see my grandmother for the warrior woman that she was to me, you have to know that her farmer father sent her to the city for schooling because he didn't know what else to do with a daughter who was so smart. In early 20th‐century Vietnam, this was an unusual thing to do with a girl. She met my grandfather there, when he was a campus activist, helping him hand out nationalist leaflets. He introduced her to his Communist friends. After the French jailed my grandfather, my grandmother courted him by sending him long letters and care packages while he was in prison. When he was finally released, they married and started a family while he struggled financially as a newspaper publisher and at other odd jobs. But in 1947 his own Communist comrades killed him as part of a party purge. He had been forewarned, and opted to go quietly rather than try to escape because he was promised that this would guarantee her safety. Before they killed him, somewhere in the mountains, my grandfather gave a soldier friend a poem he wrote for his wife. When she told me this story 8 years ago, more than half a century later, she recited his love missive from memory.

At the time of her husband's death, my grandmother had 6 children, the last born just a few weeks before. After a few years of scraping by (she ran her own one‐room school for a while), she decided to leave Hanoi, and migrated south to Saigon with her brood. She was a famously strict parent, to hear my aunts and uncles tell it. She watched them like a hawk, worked full‐time, put them all through school, and eventually rose to a leadership position in the Ministry of Social Work in South Vietnam. My memories of Saigon life are punctuated by scenes of siblings and cousins running around at her regal house, yellow stucco with porticos and black iron gates, at a corner turn in the road, past a cemetery.

On this side of the world, to see her, you would never have thought that my grandmother had led such an epic life. She never worked again after immigrating with us in 1975. She lived on Social Security checks, gardened, said Buddhist prayers, and was nanny to her grandchildren. She watched soap operas religiously, and could report their full plot lines while sitting and knitting. She bundled her many sadnesses in a contented, 4‐foot 9‐inch frame.

Having no home of her own, she would move from one child's house to another every few months so as not to wear out her welcome. But her children lived in Pennsylvania, New Jersey, Florida, Texas, and Maryland. And in most of these cities, she had a different primary care physician. She has 21 grandchildren; 8 of us are physicians. Yet the aunts and uncles told us very little about her medical care. She preferred older‐generation Vietnamese physicians and I'm not sure that they were all competent, but her children did not want to argue with an octogenarian war survivor, and we deferred to their judgment. So we would find out only incidentally, for example, that a doctor prescribed her tuberculosis drugs for a visit to Vietnam.

For many years, Ba ngoai had no major medical problems. She was hypothyroid and hypertensive but on medication and generally high functioning. She had a lumpectomy for early‐stage breast cancer. Then, a year or so after she told me the story of my grandfather's death, Alzheimer's set in. It became harder for her to report symptoms reliably, and she became mildly depressed. Her grandchildren were now birthing our own babies, and we offered these as a distraction, trying to surround her with celebrations of these new fruits of her life labors.

Ba ngoai's decline worsened 3 years ago. She became more easily fatigued, depressed, and confused. A few months before she died, she started to get dyspneic, and couldn't go for short walks any more. In retrospect, I think that her prescription for thyroid replacement somehow fell through the cracks, probably in the transfer of care from one city to another, although there remains a great deal of confusion in the family about exactly what happened. Her thyroxine levels dwindled. One evening in October of that year, at my uncle's house in Maryland, she became severely short of breath and nearly unconscious. They called her Maryland PCP, who sent her to an emergency room at a local hospital. She was admitted in severe congestive heart failure. When the hospitalist spoke with my mother and uncle, he explained that he could take some fluid off her lungs, but that she might need to be intubated and admitted to intensive care. Looking back, I guessed that she probably needed pressors and invasive monitoring. He asked them, Is this what you want? My uncle said, No, it's not. And the hospitalist and the huddle of relatives decided she should come home.

The question was, into whose care would she be discharged? My elders were wary of contacting her PCP, partly because some blamed him for not catching and addressing her symptoms sooner, partly because to even confront him with this perception would cause him, and hence them, to lose face. This seemed too excruciating a scenario to them.

So at last, my uncle called my brother, the oldest grandchild and a very talented clinician. My brother is a pulmonologist, the kind of physician who once did a history and physical on a patient complaining only of Really feeling bad, Doc, and confidently started a steroid infusion before returning the next day with test results confirming his suspicion of Wegener's granulomatosis. He took my grandmother's physical by phone, and told my uncle to increase her furosemide dose. Then he said, I'm on call, but I'll be down there tomorrow. Call everyone together. Most of my relatives were already in town; they had come at news of her decline. She became alert enough for a couple of days to see and recognize most of the faces around her, like so many markers on a long journey. And then she died, slipped away.

I find it hard to define good coordination of care. My instinct as a researcher is to list measurable elements, but the tools we currently have generate metrics that are either reductionistsuch as how rapidly a physician returns a patient's callor so global that they no longer seem actionablesuch as patient satisfaction. But if such metrics set the goal in the distance, it seems useful to also define its counterpartdiscoordinationas a marker of the reality we would like to leave behind us as far as possible. Discoordination includes elements of discontinuity (lost patient history), fragmentation (actions by multiple players), overuse and/or inappropriate use of services, and ultimately, ineffective care (that is, the patient's needs go unmet).

My experience of discoordination was that of a Rube Goldberg contraption. It's composed of innumerable subtasks, each cleverly designed as the easiest solution to a seemingly short‐term problem, as quick fixes, but that in aggregate generate such chaos that the ultimate purpose is lost. They include acts of denial, lies to avoid embarrassment or conflict, and choices of convenience. My mother and her siblings accommodated my grandmother's choice of physicians by (secretly) not always adhering to care recommendations they didn't agree with, instead of challenging her. They took her to different physicians in different cities rather than risk embarrassing (due to an exaggerated sense of the smallness of the Vietnamese community) any one physician by dropping him. Her grandchildren, despite our medical training, found it culturally easier to defer to our elders than to intervene in substandard care. And none of her physicians aggressively followed up to ensure that a frail Alzheimer's patient was getting the care she needed. This is not to suggest that coordination is a simple task because Rube Goldberg machines make simple tasks complicated. Rather, it is a depiction of how indirectly we tend to address the problem.

I imagine a different course of events for my grandmother in the absence of discoordination. What if her children and physicians had understood and acknowledged to one another that her care was fragmented and therefore suboptimal? What if we grandchildren had confronted both Ba Ngoai and our parents sooner about their choice of physicians and offered to take on more of the burden of helping with her care decisions? Would we, as physicians, have been better able to ensure that her providers made rational clinical decisions? And what if she and her family had consistently recognized a single physician as her medical home? Snowbirding is hardly a rare phenomenon among Medicare patients; we could have designated one physician as primarily responsible for coordinating her care even without limiting her travel.

Care coordination is an inherently human activity. Supportive elements such as efficient transfer of medical information, resources for patient education and self‐care, and adequate reimbursement can take us to the brink of, but not actually bridge, the chasm that we want to cross. Traversing that divide sometimes requires settling turf issues over undesirable responsibilities between different physicians and between physicians and other providers; clarifying who has primary responsibility for different types of decisions (I lead on cardiac issues and her son leads on health maintenance); and the violation of cultural norms of patients, families, and/or providers. These can be uncomfortable, unpleasant conversations that at times seem beside the point. But in aggregate, they are the work of coordination, because they force us to align our expectations of one another. No level of information technology could have dismantled the Rube Goldberg machine that trapped my grandmother. Her last of many lessons for me was that emotional courage, honesty, and perseverance offer a much more direct path through the muck.

I was 12 years old before I knew her actual name, Le Thi Canh, because we always called her Ba ngoai. She was my grandmother, and this is the story of how she died.

To see my grandmother for the warrior woman that she was to me, you have to know that her farmer father sent her to the city for schooling because he didn't know what else to do with a daughter who was so smart. In early 20th‐century Vietnam, this was an unusual thing to do with a girl. She met my grandfather there, when he was a campus activist, helping him hand out nationalist leaflets. He introduced her to his Communist friends. After the French jailed my grandfather, my grandmother courted him by sending him long letters and care packages while he was in prison. When he was finally released, they married and started a family while he struggled financially as a newspaper publisher and at other odd jobs. But in 1947 his own Communist comrades killed him as part of a party purge. He had been forewarned, and opted to go quietly rather than try to escape because he was promised that this would guarantee her safety. Before they killed him, somewhere in the mountains, my grandfather gave a soldier friend a poem he wrote for his wife. When she told me this story 8 years ago, more than half a century later, she recited his love missive from memory.

At the time of her husband's death, my grandmother had 6 children, the last born just a few weeks before. After a few years of scraping by (she ran her own one‐room school for a while), she decided to leave Hanoi, and migrated south to Saigon with her brood. She was a famously strict parent, to hear my aunts and uncles tell it. She watched them like a hawk, worked full‐time, put them all through school, and eventually rose to a leadership position in the Ministry of Social Work in South Vietnam. My memories of Saigon life are punctuated by scenes of siblings and cousins running around at her regal house, yellow stucco with porticos and black iron gates, at a corner turn in the road, past a cemetery.

On this side of the world, to see her, you would never have thought that my grandmother had led such an epic life. She never worked again after immigrating with us in 1975. She lived on Social Security checks, gardened, said Buddhist prayers, and was nanny to her grandchildren. She watched soap operas religiously, and could report their full plot lines while sitting and knitting. She bundled her many sadnesses in a contented, 4‐foot 9‐inch frame.

Having no home of her own, she would move from one child's house to another every few months so as not to wear out her welcome. But her children lived in Pennsylvania, New Jersey, Florida, Texas, and Maryland. And in most of these cities, she had a different primary care physician. She has 21 grandchildren; 8 of us are physicians. Yet the aunts and uncles told us very little about her medical care. She preferred older‐generation Vietnamese physicians and I'm not sure that they were all competent, but her children did not want to argue with an octogenarian war survivor, and we deferred to their judgment. So we would find out only incidentally, for example, that a doctor prescribed her tuberculosis drugs for a visit to Vietnam.

For many years, Ba ngoai had no major medical problems. She was hypothyroid and hypertensive but on medication and generally high functioning. She had a lumpectomy for early‐stage breast cancer. Then, a year or so after she told me the story of my grandfather's death, Alzheimer's set in. It became harder for her to report symptoms reliably, and she became mildly depressed. Her grandchildren were now birthing our own babies, and we offered these as a distraction, trying to surround her with celebrations of these new fruits of her life labors.

Ba ngoai's decline worsened 3 years ago. She became more easily fatigued, depressed, and confused. A few months before she died, she started to get dyspneic, and couldn't go for short walks any more. In retrospect, I think that her prescription for thyroid replacement somehow fell through the cracks, probably in the transfer of care from one city to another, although there remains a great deal of confusion in the family about exactly what happened. Her thyroxine levels dwindled. One evening in October of that year, at my uncle's house in Maryland, she became severely short of breath and nearly unconscious. They called her Maryland PCP, who sent her to an emergency room at a local hospital. She was admitted in severe congestive heart failure. When the hospitalist spoke with my mother and uncle, he explained that he could take some fluid off her lungs, but that she might need to be intubated and admitted to intensive care. Looking back, I guessed that she probably needed pressors and invasive monitoring. He asked them, Is this what you want? My uncle said, No, it's not. And the hospitalist and the huddle of relatives decided she should come home.

The question was, into whose care would she be discharged? My elders were wary of contacting her PCP, partly because some blamed him for not catching and addressing her symptoms sooner, partly because to even confront him with this perception would cause him, and hence them, to lose face. This seemed too excruciating a scenario to them.

So at last, my uncle called my brother, the oldest grandchild and a very talented clinician. My brother is a pulmonologist, the kind of physician who once did a history and physical on a patient complaining only of Really feeling bad, Doc, and confidently started a steroid infusion before returning the next day with test results confirming his suspicion of Wegener's granulomatosis. He took my grandmother's physical by phone, and told my uncle to increase her furosemide dose. Then he said, I'm on call, but I'll be down there tomorrow. Call everyone together. Most of my relatives were already in town; they had come at news of her decline. She became alert enough for a couple of days to see and recognize most of the faces around her, like so many markers on a long journey. And then she died, slipped away.

I find it hard to define good coordination of care. My instinct as a researcher is to list measurable elements, but the tools we currently have generate metrics that are either reductionistsuch as how rapidly a physician returns a patient's callor so global that they no longer seem actionablesuch as patient satisfaction. But if such metrics set the goal in the distance, it seems useful to also define its counterpartdiscoordinationas a marker of the reality we would like to leave behind us as far as possible. Discoordination includes elements of discontinuity (lost patient history), fragmentation (actions by multiple players), overuse and/or inappropriate use of services, and ultimately, ineffective care (that is, the patient's needs go unmet).

My experience of discoordination was that of a Rube Goldberg contraption. It's composed of innumerable subtasks, each cleverly designed as the easiest solution to a seemingly short‐term problem, as quick fixes, but that in aggregate generate such chaos that the ultimate purpose is lost. They include acts of denial, lies to avoid embarrassment or conflict, and choices of convenience. My mother and her siblings accommodated my grandmother's choice of physicians by (secretly) not always adhering to care recommendations they didn't agree with, instead of challenging her. They took her to different physicians in different cities rather than risk embarrassing (due to an exaggerated sense of the smallness of the Vietnamese community) any one physician by dropping him. Her grandchildren, despite our medical training, found it culturally easier to defer to our elders than to intervene in substandard care. And none of her physicians aggressively followed up to ensure that a frail Alzheimer's patient was getting the care she needed. This is not to suggest that coordination is a simple task because Rube Goldberg machines make simple tasks complicated. Rather, it is a depiction of how indirectly we tend to address the problem.

I imagine a different course of events for my grandmother in the absence of discoordination. What if her children and physicians had understood and acknowledged to one another that her care was fragmented and therefore suboptimal? What if we grandchildren had confronted both Ba Ngoai and our parents sooner about their choice of physicians and offered to take on more of the burden of helping with her care decisions? Would we, as physicians, have been better able to ensure that her providers made rational clinical decisions? And what if she and her family had consistently recognized a single physician as her medical home? Snowbirding is hardly a rare phenomenon among Medicare patients; we could have designated one physician as primarily responsible for coordinating her care even without limiting her travel.

Care coordination is an inherently human activity. Supportive elements such as efficient transfer of medical information, resources for patient education and self‐care, and adequate reimbursement can take us to the brink of, but not actually bridge, the chasm that we want to cross. Traversing that divide sometimes requires settling turf issues over undesirable responsibilities between different physicians and between physicians and other providers; clarifying who has primary responsibility for different types of decisions (I lead on cardiac issues and her son leads on health maintenance); and the violation of cultural norms of patients, families, and/or providers. These can be uncomfortable, unpleasant conversations that at times seem beside the point. But in aggregate, they are the work of coordination, because they force us to align our expectations of one another. No level of information technology could have dismantled the Rube Goldberg machine that trapped my grandmother. Her last of many lessons for me was that emotional courage, honesty, and perseverance offer a much more direct path through the muck.

Issue
Journal of Hospital Medicine - 4(4)
Issue
Journal of Hospital Medicine - 4(4)
Page Number
259-260
Page Number
259-260
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Dismantling Rube Goldberg: Cutting through chaos to achieve coordinated care
Display Headline
Dismantling Rube Goldberg: Cutting through chaos to achieve coordinated care
Legacy Keywords
coordination of care, geriatric patient care, diabetes, Alzheimer's disease
Legacy Keywords
coordination of care, geriatric patient care, diabetes, Alzheimer's disease
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Copyright © 2009 Society of Hospital Medicine
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