POEMS syndrome: a significant clinical response to lenalidomide

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POEMS syndrome is a rare paraneoplastic syndrome whose cause is unknown. In this case of POEMS syndrome, the patient showed significant clinical improvement after treatment with lenalidomide. Of note is that although polyneuropathy is a known side effect of IMiDs, lenalidomide is an immune modulator that is cytotoxic to malignant plasma cells but has a much lower risk of peripheral neuropathy.

 

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POEMS syndrome is a rare paraneoplastic syndrome whose cause is unknown. In this case of POEMS syndrome, the patient showed significant clinical improvement after treatment with lenalidomide. Of note is that although polyneuropathy is a known side effect of IMiDs, lenalidomide is an immune modulator that is cytotoxic to malignant plasma cells but has a much lower risk of peripheral neuropathy.

 

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POEMS syndrome is a rare paraneoplastic syndrome whose cause is unknown. In this case of POEMS syndrome, the patient showed significant clinical improvement after treatment with lenalidomide. Of note is that although polyneuropathy is a known side effect of IMiDs, lenalidomide is an immune modulator that is cytotoxic to malignant plasma cells but has a much lower risk of peripheral neuropathy.

 

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POEMS syndrome: a significant clinical response to lenalidomide
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Fish "Sticks"

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Nicholas Connors, MD
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Rash on a Man's Hand; Itchy Lower-Body Lesions on a Woman

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Physeal Fracture of the Distal Femur in a Newborn: Role of Arthrography

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Postpartum Tuberculous Sacroiliitis

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Use of Fresh Osteochondral Glenoid Allograft to Treat Posteroinferior Bone Loss in Chronic Posterior Shoulder Instability

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Postoperative Death Associated With a Reverse Prosthesis

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Bronchial Breathing and Resonant Percussion—An Important Combination of Signs in Pneumothorax

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Smoking Cessation Can Be Toxic to Your Health

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Regeneration of a Discoid Meniscus After Arthroscopic Saucerization

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Regeneration of a Discoid Meniscus After Arthroscopic Saucerization
Display Headline
Regeneration of a Discoid Meniscus After Arthroscopic Saucerization
Legacy Keywords
ajo, the american journal of orthopedics, meniscus, pain, pediatric orthopedics, knee, arthroscopy
Legacy Keywords
ajo, the american journal of orthopedics, meniscus, pain, pediatric orthopedics, knee, arthroscopy
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