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Timothy S. Wang, MD, Patrick J. Byrne, MD, FACS, Lisa K. Jacobs, MD, and Janis M. Taube, MD
Merkel cell carcinoma (MCC) is a rare, aggressive, and often fatal cutaneous malignancy that is not usually suspected at the time of biopsy. Because of its increasing incidence and the discovery of a possible viral association, interest in MCC has escalated. Recent effort has broadened our breadth of knowledge regarding MCC and developed instruments to improve data collection and future study. This article provides an update on current thinking about the Merkel cell and MCC.
*For a PDF of the full article, click on the link to the left of this introduction.
Timothy S. Wang, MD, Patrick J. Byrne, MD, FACS, Lisa K. Jacobs, MD, and Janis M. Taube, MD
Merkel cell carcinoma (MCC) is a rare, aggressive, and often fatal cutaneous malignancy that is not usually suspected at the time of biopsy. Because of its increasing incidence and the discovery of a possible viral association, interest in MCC has escalated. Recent effort has broadened our breadth of knowledge regarding MCC and developed instruments to improve data collection and future study. This article provides an update on current thinking about the Merkel cell and MCC.
*For a PDF of the full article, click on the link to the left of this introduction.
Timothy S. Wang, MD, Patrick J. Byrne, MD, FACS, Lisa K. Jacobs, MD, and Janis M. Taube, MD
Merkel cell carcinoma (MCC) is a rare, aggressive, and often fatal cutaneous malignancy that is not usually suspected at the time of biopsy. Because of its increasing incidence and the discovery of a possible viral association, interest in MCC has escalated. Recent effort has broadened our breadth of knowledge regarding MCC and developed instruments to improve data collection and future study. This article provides an update on current thinking about the Merkel cell and MCC.
*For a PDF of the full article, click on the link to the left of this introduction.
This article provides an update on current thinking, including novel insights into the Merkel cell; a review of the 2010 National Comprehensive Cancer Network (NCCN) therapeutic guidelines and new American Joint Committee on Cancer (AJCC) staging system; recommendations for pathologic reporting and new diagnostic codes; and the recently described Merkel cell polyoma virus (MCPyV).