User login
Type 2 diabetes and depressive symptoms have a bidirectional association: People with diabetes are at increased risk of developing depressive symptoms, and those with depressive symptoms are at increased risk of developing diabetes, according to a report in the June 18 issue of the Journal of the American Medical Association.
These results, from a population-based longitudinal study that followed approximately 5,000 middle-aged subjects for up to 5 years, are the first to demonstrate a bidirectional association between “these two serious long-term diseases,” said Dr. Sherita Hill Golden of Johns Hopkins University, Baltimore, and her associates.
The findings suggest that interventions targeting depression may complement diabetes prevention strategies, and that patients who already have diabetes perhaps should be screened for depressive symptoms, the investigators noted (JAMA 2008;299:2751-9).
They examined the relationship between diabetes and depression using data from a multicenter longitudinal cohort study of men and women whose mean age was in the 60s and who resided in six U.S. communities. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression (CES-D) scale, a 20-item questionnaire designed to evaluate such symptoms in community populations.
Among subjects who had no depressive symptoms at baseline, those with type 2 diabetes were at significantly higher risk for developing depressive symptoms during follow-up, independent of their body mass index, socioeconomic status, and comorbidities.
It is possible that the psychological stress of managing diabetes may lead to depression, or that the complications and comorbidities of the disease may increase depressive symptoms, Dr. Golden and her associates said.
In addition, subjects who had depressive symptoms at baseline were at modestly increased risk of developing diabetes during follow-up, independent of sociodemographic, economic, and metabolic factors.
The National Heart, Lung, and Blood Institute was a sponsor of this study. Dr. Golden serves on the Merck Clinical Diabetes Advisory Board and has received an unrestricted educational grant from Novo Nordisk in the past.
Type 2 diabetes and depressive symptoms have a bidirectional association: People with diabetes are at increased risk of developing depressive symptoms, and those with depressive symptoms are at increased risk of developing diabetes, according to a report in the June 18 issue of the Journal of the American Medical Association.
These results, from a population-based longitudinal study that followed approximately 5,000 middle-aged subjects for up to 5 years, are the first to demonstrate a bidirectional association between “these two serious long-term diseases,” said Dr. Sherita Hill Golden of Johns Hopkins University, Baltimore, and her associates.
The findings suggest that interventions targeting depression may complement diabetes prevention strategies, and that patients who already have diabetes perhaps should be screened for depressive symptoms, the investigators noted (JAMA 2008;299:2751-9).
They examined the relationship between diabetes and depression using data from a multicenter longitudinal cohort study of men and women whose mean age was in the 60s and who resided in six U.S. communities. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression (CES-D) scale, a 20-item questionnaire designed to evaluate such symptoms in community populations.
Among subjects who had no depressive symptoms at baseline, those with type 2 diabetes were at significantly higher risk for developing depressive symptoms during follow-up, independent of their body mass index, socioeconomic status, and comorbidities.
It is possible that the psychological stress of managing diabetes may lead to depression, or that the complications and comorbidities of the disease may increase depressive symptoms, Dr. Golden and her associates said.
In addition, subjects who had depressive symptoms at baseline were at modestly increased risk of developing diabetes during follow-up, independent of sociodemographic, economic, and metabolic factors.
The National Heart, Lung, and Blood Institute was a sponsor of this study. Dr. Golden serves on the Merck Clinical Diabetes Advisory Board and has received an unrestricted educational grant from Novo Nordisk in the past.
Type 2 diabetes and depressive symptoms have a bidirectional association: People with diabetes are at increased risk of developing depressive symptoms, and those with depressive symptoms are at increased risk of developing diabetes, according to a report in the June 18 issue of the Journal of the American Medical Association.
These results, from a population-based longitudinal study that followed approximately 5,000 middle-aged subjects for up to 5 years, are the first to demonstrate a bidirectional association between “these two serious long-term diseases,” said Dr. Sherita Hill Golden of Johns Hopkins University, Baltimore, and her associates.
The findings suggest that interventions targeting depression may complement diabetes prevention strategies, and that patients who already have diabetes perhaps should be screened for depressive symptoms, the investigators noted (JAMA 2008;299:2751-9).
They examined the relationship between diabetes and depression using data from a multicenter longitudinal cohort study of men and women whose mean age was in the 60s and who resided in six U.S. communities. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression (CES-D) scale, a 20-item questionnaire designed to evaluate such symptoms in community populations.
Among subjects who had no depressive symptoms at baseline, those with type 2 diabetes were at significantly higher risk for developing depressive symptoms during follow-up, independent of their body mass index, socioeconomic status, and comorbidities.
It is possible that the psychological stress of managing diabetes may lead to depression, or that the complications and comorbidities of the disease may increase depressive symptoms, Dr. Golden and her associates said.
In addition, subjects who had depressive symptoms at baseline were at modestly increased risk of developing diabetes during follow-up, independent of sociodemographic, economic, and metabolic factors.
The National Heart, Lung, and Blood Institute was a sponsor of this study. Dr. Golden serves on the Merck Clinical Diabetes Advisory Board and has received an unrestricted educational grant from Novo Nordisk in the past.