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Cancer Data Trends 2024: Hepatocellular Carcinoma
References

1. Pinheiro PS, Jones PD, Medina H, et al. Incidence of etiology-specific hepatocellular carcinoma: diIverging trends and significant heterogeneity by race and ethnicity. Clin Gastroenterol Hepatol. Published online September 6, 2023. doi:10.1016/j.cgh.2023.08.016
 

2. Ju MR, Karalis JD, Chansard M, et al. Variation of hepatocellular carcinoma treatment patterns and survival across geographic regions in a veteran population. Ann Surg Oncol. 2022;29(13):8413-8420. doi:10.1245/s10434-022-12390-7
 

3. Veterans Health Administration. VA collaborative consensus on a pathway for the development of a multidisciplinary team to manage hepatocellular carcinoma. VA Liver Cancer Summit; March 8, 2019; Miami, FL. Accessed December 14, 2023. https://www.hepatitis.va.gov/pdf/HCC-multidisciplinary-management-best-practices.pdf
 

4. Emerson L. Hepatocellular carcinoma treatment, survival varies among VA regions. US Medicine. Published June 12, 2023. Accessed December 14, 2023. https://www.usmedicine.com/clinical-topics/cancer/hepatocellular-carcinoma/hepatocellular-carcinoma-treatment-survival-varies-among-va-regions/
 

5. Agarwal PD, Haftoglou BA, Ziemlewicz TJ, Lucey MR, Said A. Psychosocial barriers and their impact on hepatocellular carcinoma care in US veterans: tumor board model of care. Fed Pract. 2022;39(suppl 2):S32-S36. doi:10.12788/fp.0272
 

6. Ito T, Nguyen MH. Perspectives on the underlying etiology of HCC and its effects on treatment outcomes. J Hepatocell Carcinoma. 2023;10:413-428. doi:10.2147/JHC.S347959
 

7. Garren P, Serper M. Chronic hepatitis B in US veterans. Curr Hepatol Rep. 2019;18(3):310-315. doi:10.1007/s11901-019-00479-9
 

8. US Department of Veteran Affairs. Hepatitis C: information for veterans. Published November 2022. Accessed December 14, 2023. https://www.hepatitis.va.gov/pdf/Hepatitis-C-Factsheet-Veterans.pdf

9. Janevska D, Chaloska-Ivanova V, Janevski V. Hepatocellular carcinoma: risk factors, diagnosis and treatment. Open Access Maced J Med Sci. 2015;3(4):732-736. doi:10.3889/oamjms.2015.111
 

10. Elderkin J, Al Hallak N, Azmi AS, et al. Hepatocellular carcinoma: surveillance, diagnosis, evaluation and management. Cancers (Basel). 2023;15(21):5118. doi:http://doi.org/10.3390/cancers15215118
 

11. Wei H, Yang J, Lu R, et al. m6A modification of AC026356.1 facilitates hepatocellular carcinoma progression by regulating the IGF2BP1-IL11 axis. Sci Rep. 2023;13(1):19124. doi:10.1038/s41598-023-45449-w
 

12. Espinoza M, Muquith M, Lim M, Zhu H, Singal AG, Hsiehchen D. Disease etiology and outcomes after atezolizumab plus bevacizumab in hepatocellular carcinoma: post-hoc analysis of IMbrave150. Gastroenterology. 2023;165(1):286-288.e4. doi:10.1053/j.gastro.2023.02.042
 

13. Zhang H, Zhang W, Jiang L, Chen Y. Recent advances in systemic therapy for hepatocellular carcinoma. Biomark Res. 2022;10(1):3. doi:10.1186/s40364-021-00350-4
 

14. Johnson P, Zhou Q, Dao DY, Lo YMD. Circulating biomarkers in the diagnosis and management of hepatocellular carcinoma. Nat Rev Gastroenterol Hepatol. 2022;19(10):670-681. doi:10.1038/s41575-022-00620-y
 

15. US Department of Veteran Affairs. VA Cooperative Studies Program (CSP). CSP #2023 PREventing liver cancer Mortality through Imaging with Ultrasound vs MRI (PREMIUM STUDY). Updated July 2022. Accessed December 14, 2023. https://www.vacsp.research.va.gov /CSP_2023/CSP_2023.asp

Author and Disclosure Information

Reviewed by Cynthia Moylan, MD, MHS
Associate Professor of Medicine
GI Clinical Research Unite Co-Director
Duke University Health System
Durham VA Health System
Durham, NC

Dr. Moylan has no relevant financial relationships to disclose.

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Author and Disclosure Information

Reviewed by Cynthia Moylan, MD, MHS
Associate Professor of Medicine
GI Clinical Research Unite Co-Director
Duke University Health System
Durham VA Health System
Durham, NC

Dr. Moylan has no relevant financial relationships to disclose.

Author and Disclosure Information

Reviewed by Cynthia Moylan, MD, MHS
Associate Professor of Medicine
GI Clinical Research Unite Co-Director
Duke University Health System
Durham VA Health System
Durham, NC

Dr. Moylan has no relevant financial relationships to disclose.

References

1. Pinheiro PS, Jones PD, Medina H, et al. Incidence of etiology-specific hepatocellular carcinoma: diIverging trends and significant heterogeneity by race and ethnicity. Clin Gastroenterol Hepatol. Published online September 6, 2023. doi:10.1016/j.cgh.2023.08.016
 

2. Ju MR, Karalis JD, Chansard M, et al. Variation of hepatocellular carcinoma treatment patterns and survival across geographic regions in a veteran population. Ann Surg Oncol. 2022;29(13):8413-8420. doi:10.1245/s10434-022-12390-7
 

3. Veterans Health Administration. VA collaborative consensus on a pathway for the development of a multidisciplinary team to manage hepatocellular carcinoma. VA Liver Cancer Summit; March 8, 2019; Miami, FL. Accessed December 14, 2023. https://www.hepatitis.va.gov/pdf/HCC-multidisciplinary-management-best-practices.pdf
 

4. Emerson L. Hepatocellular carcinoma treatment, survival varies among VA regions. US Medicine. Published June 12, 2023. Accessed December 14, 2023. https://www.usmedicine.com/clinical-topics/cancer/hepatocellular-carcinoma/hepatocellular-carcinoma-treatment-survival-varies-among-va-regions/
 

5. Agarwal PD, Haftoglou BA, Ziemlewicz TJ, Lucey MR, Said A. Psychosocial barriers and their impact on hepatocellular carcinoma care in US veterans: tumor board model of care. Fed Pract. 2022;39(suppl 2):S32-S36. doi:10.12788/fp.0272
 

6. Ito T, Nguyen MH. Perspectives on the underlying etiology of HCC and its effects on treatment outcomes. J Hepatocell Carcinoma. 2023;10:413-428. doi:10.2147/JHC.S347959
 

7. Garren P, Serper M. Chronic hepatitis B in US veterans. Curr Hepatol Rep. 2019;18(3):310-315. doi:10.1007/s11901-019-00479-9
 

8. US Department of Veteran Affairs. Hepatitis C: information for veterans. Published November 2022. Accessed December 14, 2023. https://www.hepatitis.va.gov/pdf/Hepatitis-C-Factsheet-Veterans.pdf

9. Janevska D, Chaloska-Ivanova V, Janevski V. Hepatocellular carcinoma: risk factors, diagnosis and treatment. Open Access Maced J Med Sci. 2015;3(4):732-736. doi:10.3889/oamjms.2015.111
 

10. Elderkin J, Al Hallak N, Azmi AS, et al. Hepatocellular carcinoma: surveillance, diagnosis, evaluation and management. Cancers (Basel). 2023;15(21):5118. doi:http://doi.org/10.3390/cancers15215118
 

11. Wei H, Yang J, Lu R, et al. m6A modification of AC026356.1 facilitates hepatocellular carcinoma progression by regulating the IGF2BP1-IL11 axis. Sci Rep. 2023;13(1):19124. doi:10.1038/s41598-023-45449-w
 

12. Espinoza M, Muquith M, Lim M, Zhu H, Singal AG, Hsiehchen D. Disease etiology and outcomes after atezolizumab plus bevacizumab in hepatocellular carcinoma: post-hoc analysis of IMbrave150. Gastroenterology. 2023;165(1):286-288.e4. doi:10.1053/j.gastro.2023.02.042
 

13. Zhang H, Zhang W, Jiang L, Chen Y. Recent advances in systemic therapy for hepatocellular carcinoma. Biomark Res. 2022;10(1):3. doi:10.1186/s40364-021-00350-4
 

14. Johnson P, Zhou Q, Dao DY, Lo YMD. Circulating biomarkers in the diagnosis and management of hepatocellular carcinoma. Nat Rev Gastroenterol Hepatol. 2022;19(10):670-681. doi:10.1038/s41575-022-00620-y
 

15. US Department of Veteran Affairs. VA Cooperative Studies Program (CSP). CSP #2023 PREventing liver cancer Mortality through Imaging with Ultrasound vs MRI (PREMIUM STUDY). Updated July 2022. Accessed December 14, 2023. https://www.vacsp.research.va.gov /CSP_2023/CSP_2023.asp

References

1. Pinheiro PS, Jones PD, Medina H, et al. Incidence of etiology-specific hepatocellular carcinoma: diIverging trends and significant heterogeneity by race and ethnicity. Clin Gastroenterol Hepatol. Published online September 6, 2023. doi:10.1016/j.cgh.2023.08.016
 

2. Ju MR, Karalis JD, Chansard M, et al. Variation of hepatocellular carcinoma treatment patterns and survival across geographic regions in a veteran population. Ann Surg Oncol. 2022;29(13):8413-8420. doi:10.1245/s10434-022-12390-7
 

3. Veterans Health Administration. VA collaborative consensus on a pathway for the development of a multidisciplinary team to manage hepatocellular carcinoma. VA Liver Cancer Summit; March 8, 2019; Miami, FL. Accessed December 14, 2023. https://www.hepatitis.va.gov/pdf/HCC-multidisciplinary-management-best-practices.pdf
 

4. Emerson L. Hepatocellular carcinoma treatment, survival varies among VA regions. US Medicine. Published June 12, 2023. Accessed December 14, 2023. https://www.usmedicine.com/clinical-topics/cancer/hepatocellular-carcinoma/hepatocellular-carcinoma-treatment-survival-varies-among-va-regions/
 

5. Agarwal PD, Haftoglou BA, Ziemlewicz TJ, Lucey MR, Said A. Psychosocial barriers and their impact on hepatocellular carcinoma care in US veterans: tumor board model of care. Fed Pract. 2022;39(suppl 2):S32-S36. doi:10.12788/fp.0272
 

6. Ito T, Nguyen MH. Perspectives on the underlying etiology of HCC and its effects on treatment outcomes. J Hepatocell Carcinoma. 2023;10:413-428. doi:10.2147/JHC.S347959
 

7. Garren P, Serper M. Chronic hepatitis B in US veterans. Curr Hepatol Rep. 2019;18(3):310-315. doi:10.1007/s11901-019-00479-9
 

8. US Department of Veteran Affairs. Hepatitis C: information for veterans. Published November 2022. Accessed December 14, 2023. https://www.hepatitis.va.gov/pdf/Hepatitis-C-Factsheet-Veterans.pdf

9. Janevska D, Chaloska-Ivanova V, Janevski V. Hepatocellular carcinoma: risk factors, diagnosis and treatment. Open Access Maced J Med Sci. 2015;3(4):732-736. doi:10.3889/oamjms.2015.111
 

10. Elderkin J, Al Hallak N, Azmi AS, et al. Hepatocellular carcinoma: surveillance, diagnosis, evaluation and management. Cancers (Basel). 2023;15(21):5118. doi:http://doi.org/10.3390/cancers15215118
 

11. Wei H, Yang J, Lu R, et al. m6A modification of AC026356.1 facilitates hepatocellular carcinoma progression by regulating the IGF2BP1-IL11 axis. Sci Rep. 2023;13(1):19124. doi:10.1038/s41598-023-45449-w
 

12. Espinoza M, Muquith M, Lim M, Zhu H, Singal AG, Hsiehchen D. Disease etiology and outcomes after atezolizumab plus bevacizumab in hepatocellular carcinoma: post-hoc analysis of IMbrave150. Gastroenterology. 2023;165(1):286-288.e4. doi:10.1053/j.gastro.2023.02.042
 

13. Zhang H, Zhang W, Jiang L, Chen Y. Recent advances in systemic therapy for hepatocellular carcinoma. Biomark Res. 2022;10(1):3. doi:10.1186/s40364-021-00350-4
 

14. Johnson P, Zhou Q, Dao DY, Lo YMD. Circulating biomarkers in the diagnosis and management of hepatocellular carcinoma. Nat Rev Gastroenterol Hepatol. 2022;19(10):670-681. doi:10.1038/s41575-022-00620-y
 

15. US Department of Veteran Affairs. VA Cooperative Studies Program (CSP). CSP #2023 PREventing liver cancer Mortality through Imaging with Ultrasound vs MRI (PREMIUM STUDY). Updated July 2022. Accessed December 14, 2023. https://www.vacsp.research.va.gov /CSP_2023/CSP_2023.asp

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