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The authors reply, “A focused investigation of expedited, stack of three shocks versus chest compressions first followed by single shocks for monitored ventricular fibrillation/ventricular tachycardia cardiopulmonary arrest in an in‐hospital setting”

We appreciate the opportunity to continue dialogue regarding the optimal timing of defibrillation, standardized guidelines, and healthy skepticism as to whether they apply to all settings and patient populations. The transition to a single shock followed by resumption of chest compressions over 3 stacked shocks represents the integration of 2 concepts into a single algorithm.[1] The first reflects concern about delays in chest compressions related to rhythm analysis and charge of an automated external defibrillator. This justified a single shock followed by chest compressions to avoid unnecessary pauses. The same guidelines also recommended 2 minutes of cardiopulmonary resuscitation (CPR) prior to the initial and each subsequent defibrillation attempt, providing substrate to the myocardium and increasing the likelihood of shock success.[2, 3, 4] The underlying physiological concept is described by Weisfeldt and Becker as part of their 3‐phase model of ventricular fibrillation.[2, 5] Large randomized out‐of‐hospital studies have demonstrated that high‐quality CPR may prime the heart before defibrillation, as suggested by the 3‐phase model.[6, 7, 8]

Regardless of the theoretical construct(s) upon which the original recommendations were based, we agree with Mr. Stewart that these are misapplied to the inpatient setting that allow for expeditious attempts at defibrillation and stacking of subsequent attempts.

Disclosure

Nothing to report.

References
  1. 2005 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care part 5: electrical therapies. Circulation. 2005;112:IV‐35IV‐46.
  2. 2005 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care part 4: adult basic life support. Circulation. 2005;112:IV‐19IV‐34.
  3. Cobb LA, Fahrenbruch CE, Walsh TR, et al. Influence of cardiopulmonary resuscitation prior to defibrillation in patients with out‐of‐hospital ventricular fibrillation. JAMA. 1999;281:11821188.
  4. Wik L, Hansen TB, Fylling F, et al. Delaying defibrillation to give basic cardiopulmonary resuscitation to patients with out‐of‐hospital ventricular fibrillation: a randomized trial. JAMA. 2003;289:13891395.
  5. Weisfeldt ML, Becker LB. Resuscitation after cardiac arrest: a 3‐phase time‐sensitive model. JAMA. 2002;288:30353038.
  6. Stiell IG, Callaway C, Davis D, et al. Resuscitation Outcomes Consortium (ROC) PRIMED cardiac arrest trial methods: part 2: rationale and methodology for “Analyze Later vs. Analyze Early” protocol. Resuscitation. 2008;78(2):186195.
  7. Stiell IG, Nichol G, Leroux BG, et al.; the Resuscitation Outcomes Consortium (ROC) Investigators. Early versus later rhythm analysis in patients with out‐of‐hospital cardiac arrest. N Engl J Med. 2011;365(9):787797.
  8. Rea T, Prince D, Morrison L, et al. Association between survival and early versus later rhythm analysis in out‐of‐hospital cardiac arrest: do agency‐level factors influence outcomes? Ann Emerg Med. 2014;64:18.
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We appreciate the opportunity to continue dialogue regarding the optimal timing of defibrillation, standardized guidelines, and healthy skepticism as to whether they apply to all settings and patient populations. The transition to a single shock followed by resumption of chest compressions over 3 stacked shocks represents the integration of 2 concepts into a single algorithm.[1] The first reflects concern about delays in chest compressions related to rhythm analysis and charge of an automated external defibrillator. This justified a single shock followed by chest compressions to avoid unnecessary pauses. The same guidelines also recommended 2 minutes of cardiopulmonary resuscitation (CPR) prior to the initial and each subsequent defibrillation attempt, providing substrate to the myocardium and increasing the likelihood of shock success.[2, 3, 4] The underlying physiological concept is described by Weisfeldt and Becker as part of their 3‐phase model of ventricular fibrillation.[2, 5] Large randomized out‐of‐hospital studies have demonstrated that high‐quality CPR may prime the heart before defibrillation, as suggested by the 3‐phase model.[6, 7, 8]

Regardless of the theoretical construct(s) upon which the original recommendations were based, we agree with Mr. Stewart that these are misapplied to the inpatient setting that allow for expeditious attempts at defibrillation and stacking of subsequent attempts.

Disclosure

Nothing to report.

We appreciate the opportunity to continue dialogue regarding the optimal timing of defibrillation, standardized guidelines, and healthy skepticism as to whether they apply to all settings and patient populations. The transition to a single shock followed by resumption of chest compressions over 3 stacked shocks represents the integration of 2 concepts into a single algorithm.[1] The first reflects concern about delays in chest compressions related to rhythm analysis and charge of an automated external defibrillator. This justified a single shock followed by chest compressions to avoid unnecessary pauses. The same guidelines also recommended 2 minutes of cardiopulmonary resuscitation (CPR) prior to the initial and each subsequent defibrillation attempt, providing substrate to the myocardium and increasing the likelihood of shock success.[2, 3, 4] The underlying physiological concept is described by Weisfeldt and Becker as part of their 3‐phase model of ventricular fibrillation.[2, 5] Large randomized out‐of‐hospital studies have demonstrated that high‐quality CPR may prime the heart before defibrillation, as suggested by the 3‐phase model.[6, 7, 8]

Regardless of the theoretical construct(s) upon which the original recommendations were based, we agree with Mr. Stewart that these are misapplied to the inpatient setting that allow for expeditious attempts at defibrillation and stacking of subsequent attempts.

Disclosure

Nothing to report.

References
  1. 2005 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care part 5: electrical therapies. Circulation. 2005;112:IV‐35IV‐46.
  2. 2005 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care part 4: adult basic life support. Circulation. 2005;112:IV‐19IV‐34.
  3. Cobb LA, Fahrenbruch CE, Walsh TR, et al. Influence of cardiopulmonary resuscitation prior to defibrillation in patients with out‐of‐hospital ventricular fibrillation. JAMA. 1999;281:11821188.
  4. Wik L, Hansen TB, Fylling F, et al. Delaying defibrillation to give basic cardiopulmonary resuscitation to patients with out‐of‐hospital ventricular fibrillation: a randomized trial. JAMA. 2003;289:13891395.
  5. Weisfeldt ML, Becker LB. Resuscitation after cardiac arrest: a 3‐phase time‐sensitive model. JAMA. 2002;288:30353038.
  6. Stiell IG, Callaway C, Davis D, et al. Resuscitation Outcomes Consortium (ROC) PRIMED cardiac arrest trial methods: part 2: rationale and methodology for “Analyze Later vs. Analyze Early” protocol. Resuscitation. 2008;78(2):186195.
  7. Stiell IG, Nichol G, Leroux BG, et al.; the Resuscitation Outcomes Consortium (ROC) Investigators. Early versus later rhythm analysis in patients with out‐of‐hospital cardiac arrest. N Engl J Med. 2011;365(9):787797.
  8. Rea T, Prince D, Morrison L, et al. Association between survival and early versus later rhythm analysis in out‐of‐hospital cardiac arrest: do agency‐level factors influence outcomes? Ann Emerg Med. 2014;64:18.
References
  1. 2005 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care part 5: electrical therapies. Circulation. 2005;112:IV‐35IV‐46.
  2. 2005 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care part 4: adult basic life support. Circulation. 2005;112:IV‐19IV‐34.
  3. Cobb LA, Fahrenbruch CE, Walsh TR, et al. Influence of cardiopulmonary resuscitation prior to defibrillation in patients with out‐of‐hospital ventricular fibrillation. JAMA. 1999;281:11821188.
  4. Wik L, Hansen TB, Fylling F, et al. Delaying defibrillation to give basic cardiopulmonary resuscitation to patients with out‐of‐hospital ventricular fibrillation: a randomized trial. JAMA. 2003;289:13891395.
  5. Weisfeldt ML, Becker LB. Resuscitation after cardiac arrest: a 3‐phase time‐sensitive model. JAMA. 2002;288:30353038.
  6. Stiell IG, Callaway C, Davis D, et al. Resuscitation Outcomes Consortium (ROC) PRIMED cardiac arrest trial methods: part 2: rationale and methodology for “Analyze Later vs. Analyze Early” protocol. Resuscitation. 2008;78(2):186195.
  7. Stiell IG, Nichol G, Leroux BG, et al.; the Resuscitation Outcomes Consortium (ROC) Investigators. Early versus later rhythm analysis in patients with out‐of‐hospital cardiac arrest. N Engl J Med. 2011;365(9):787797.
  8. Rea T, Prince D, Morrison L, et al. Association between survival and early versus later rhythm analysis in out‐of‐hospital cardiac arrest: do agency‐level factors influence outcomes? Ann Emerg Med. 2014;64:18.
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Journal of Hospital Medicine - 11(12)
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Journal of Hospital Medicine - 11(12)
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894-895
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894-895
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The authors reply, “A focused investigation of expedited, stack of three shocks versus chest compressions first followed by single shocks for monitored ventricular fibrillation/ventricular tachycardia cardiopulmonary arrest in an in‐hospital setting”
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The authors reply, “A focused investigation of expedited, stack of three shocks versus chest compressions first followed by single shocks for monitored ventricular fibrillation/ventricular tachycardia cardiopulmonary arrest in an in‐hospital setting”
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© 2016 Society of Hospital Medicine
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Address for correspondence and reprint requests: Steve A. Aguilar, MD, Department of Emergency Medicine, Kaiser Permanente, 4647 Zion Avenue, San Diego, CA 92120; Telephone: 619‐455‐0104; Fax: 619‐543‐3115; E‐mail: steveaguilarmd@gmail.com
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