Treatment of high LDL saves lives of those with diabetes or cardiovascular disease

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Treatment of high LDL saves lives of those with diabetes or cardiovascular disease
RACTICE RECOMMENDATIONS

Hydroxymethyl glutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin) therapy that effectively reduces low-density lipoprotein (LDL) cholesterol increases life expectancy at least as much among those with diabetes mellitus without cardiovascular disease as among those with established cardiovascular disease alone.

While this result is only based on a validated theoretical model, it was extrapolated to the entire American population, and is consistent with randomized clinical trials. Public health programs and health care providers should give as much emphasis to treating elevated LDL among those with diabetes who are still free of cardiovascular disease as among those with already established cardiovascular disease.

 
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Practice Recommendations from Key Studies

Grover SA, Coupal L, Zowall H, Weiss TW, Alexander CM.Evaluating the benefits of treating dyslipidemia: the importance of diabetes as a risk factor. Am J Med 2003; 115:122–128.

Joseph William LeMaster, MD, MPH
James J. Stevermer, MD, MSPH
Department of Family and Community Medicine, University of Missouri–Columbia. E-mail: lemasterj@health.missouri.edu.

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The Journal of Family Practice - 53(2)
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Page Number
93-105
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Author and Disclosure Information

Practice Recommendations from Key Studies

Grover SA, Coupal L, Zowall H, Weiss TW, Alexander CM.Evaluating the benefits of treating dyslipidemia: the importance of diabetes as a risk factor. Am J Med 2003; 115:122–128.

Joseph William LeMaster, MD, MPH
James J. Stevermer, MD, MSPH
Department of Family and Community Medicine, University of Missouri–Columbia. E-mail: lemasterj@health.missouri.edu.

Author and Disclosure Information

Practice Recommendations from Key Studies

Grover SA, Coupal L, Zowall H, Weiss TW, Alexander CM.Evaluating the benefits of treating dyslipidemia: the importance of diabetes as a risk factor. Am J Med 2003; 115:122–128.

Joseph William LeMaster, MD, MPH
James J. Stevermer, MD, MSPH
Department of Family and Community Medicine, University of Missouri–Columbia. E-mail: lemasterj@health.missouri.edu.

RACTICE RECOMMENDATIONS

Hydroxymethyl glutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin) therapy that effectively reduces low-density lipoprotein (LDL) cholesterol increases life expectancy at least as much among those with diabetes mellitus without cardiovascular disease as among those with established cardiovascular disease alone.

While this result is only based on a validated theoretical model, it was extrapolated to the entire American population, and is consistent with randomized clinical trials. Public health programs and health care providers should give as much emphasis to treating elevated LDL among those with diabetes who are still free of cardiovascular disease as among those with already established cardiovascular disease.

 
RACTICE RECOMMENDATIONS

Hydroxymethyl glutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin) therapy that effectively reduces low-density lipoprotein (LDL) cholesterol increases life expectancy at least as much among those with diabetes mellitus without cardiovascular disease as among those with established cardiovascular disease alone.

While this result is only based on a validated theoretical model, it was extrapolated to the entire American population, and is consistent with randomized clinical trials. Public health programs and health care providers should give as much emphasis to treating elevated LDL among those with diabetes who are still free of cardiovascular disease as among those with already established cardiovascular disease.

 
Issue
The Journal of Family Practice - 53(2)
Issue
The Journal of Family Practice - 53(2)
Page Number
93-105
Page Number
93-105
Publications
Publications
Topics
Article Type
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Treatment of high LDL saves lives of those with diabetes or cardiovascular disease
Display Headline
Treatment of high LDL saves lives of those with diabetes or cardiovascular disease
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